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PDB: 134 results

8GJV
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Chemical synthesis of maxamycins: Intermediate compound 10
Descriptor: Intermediate compound 10 for maxamycins synthesis, METHANOL
Authors:Stanfield, R.L, Moore, M.J, Boger, D.L.
Deposit date:2023-03-16
Release date:2023-06-21
Last modified:2024-04-17
Method:X-RAY DIFFRACTION (0.9 Å)
Cite:Divergent Total Synthesis and Characterization of Maxamycins.
J.Am.Chem.Soc., 145, 2023
1GGI
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CRYSTAL STRUCTURE OF AN HIV-1 NEUTRALIZING ANTIBODY 50.1 IN COMPLEX WITH ITS V3 LOOP PEPTIDE ANTIGEN
Descriptor: HIV-1 V3 LOOP PEPTIDE ANTIGEN, IGG2A 50.1 FAB (HEAVY CHAIN), IGG2A 50.1 FAB (LIGHT CHAIN)
Authors:Stanfield, R.L, Rini, J.M, Wilson, I.A.
Deposit date:1993-04-02
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of a human immunodeficiency virus type 1 neutralizing antibody, 50.1, in complex with its V3 loop peptide antigen.
Proc.Natl.Acad.Sci.USA, 90, 1993
5J74
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Fluorogen activating protein AM2.2 in complex with TO1-2p
Descriptor: 1-(17-amino-5,8-dioxo-12,15-dioxa-4,9-diazaheptadecan-1-yl)-4-{[3-(3-sulfopropyl)-1,3-benzothiazol-3-ium-2-yl]methyl}quinolin-1-ium, PHOSPHATE ION, scFv AM2.2
Authors:Stanfield, R.L, Wilson, I.A, Wu, Y.
Deposit date:2016-04-05
Release date:2016-05-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.
J Biomol Screen, 21, 2016
5J75
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Fluorogen Activating Protein AM2.2 in complex with ML342
Descriptor: N,4-dimethyl-N-{2-oxo-2-[4-(pyridin-2-yl)piperazin-1-yl]ethyl}benzene-1-sulfonamide, PHOSPHATE ION, scFv AM2.2
Authors:Stanfield, R.L, Wilson, I.A, Wu, Y.
Deposit date:2016-04-05
Release date:2016-05-04
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Discovery of Small-Molecule Nonfluorescent Inhibitors of Fluorogen-Fluorogen Activating Protein Binding Pair.
J Biomol Screen, 21, 2016
1IGF
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BU of 1igf by Molmil
CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IGG1-KAPPA B13I2 FAB (HEAVY CHAIN), IGG1-KAPPA B13I2 FAB (LIGHT CHAIN)
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:1991-03-21
Release date:1992-04-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.
Science, 248, 1990
3Q1S
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HIV-1 neutralizing antibody Z13e1 in complex with epitope display protein
Descriptor: GLYCEROL, ISOPROPYL ALCOHOL, Interleukin-22, ...
Authors:Stanfield, R.L, Julien, J.-P, Pejchal, R, Gach, J.S, Zwick, M.B, Wilson, I.A.
Deposit date:2010-12-17
Release date:2011-11-02
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure-Based Design of a Protein Immunogen that Displays an HIV-1 gp41 Neutralizing Epitope.
J.Mol.Biol., 414, 2011
6OPA
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BU of 6opa by Molmil
Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2019-04-24
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (4.084 Å)
Cite:Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
1SQ2
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Crystal Structure Analysis of the Nurse Shark New Antigen Receptor (NAR) Variable Domain in Complex With Lysozyme
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C, ...
Authors:Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A.
Deposit date:2004-03-17
Release date:2004-08-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal structure of a shark single-domain antibody V region in complex with lysozyme.
Science, 305, 2004
1T6V
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Crystal structure analysis of the nurse shark new antigen receptor (NAR) variable domain in complex with lysozyme
Descriptor: CHLORIDE ION, Lysozyme C, novel antigen receptor
Authors:Stanfield, R.L, Dooley, H, Flajnik, M.F, Wilson, I.A.
Deposit date:2004-05-07
Release date:2004-08-24
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of a shark single-domain antibody V region in complex with lysozyme.
Science, 305, 2004
6OO0
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BU of 6oo0 by Molmil
Crystal structure of bovine Fab NC-Cow1
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, NC-Cow1 heavy chain, NC-Cow1 light chain
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2019-04-22
Release date:2020-04-01
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6, 2020
1F58
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BU of 1f58 by Molmil
IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323
Descriptor: Envelope glycoprotein gp120, PROTEIN (IGG1 ANTIBODY 58.2 (HEAVY CHAIN)), PROTEIN (IGG1 ANTIBODY 58.2 (LIGHT CHAIN))
Authors:Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
Deposit date:1998-10-21
Release date:1999-02-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
2IGF
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BU of 2igf by Molmil
CRYSTAL STRUCTURES OF AN ANTIBODY TO A PEPTIDE AND ITS COMPLEX WITH PEPTIDE ANTIGEN AT 2.8 ANGSTROMS
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, IGG1-KAPPA B13I2 FAB (HEAVY CHAIN), IGG1-KAPPA B13I2 FAB (LIGHT CHAIN), ...
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:1991-03-21
Release date:1992-04-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structures of an antibody to a peptide and its complex with peptide antigen at 2.8 A.
Science, 248, 1990
5IHU
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BU of 5ihu by Molmil
Crystal structure of bovine Fab B11
Descriptor: bovine Fab B11 heavy chain, bovine Fab B11 light chain
Authors:Stanfield, R, Wilson, I.
Deposit date:2016-02-29
Release date:2016-10-05
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Conservation and diversity in the ultralong third heavy-chain complementarity-determining region of bovine antibodies.
Sci Immunol, 1, 2016
2I27
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BU of 2i27 by Molmil
Crystal Structure Analysis of the Nurse Shark New Antigen Receptor Ancestral variable domain
Descriptor: New Antigen Receptor Ancestral
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
2I24
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BU of 2i24 by Molmil
Crystal structure analysis of the nurse shark New Antigen Receptor PBLA8 variable domain
Descriptor: CHLORIDE ION, New Antigen Receptor PBLA8
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
2I26
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BU of 2i26 by Molmil
Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain in complex with lysozyme
Descriptor: Lysozyme C, New Antigen Receptor Ancestral, SULFATE ION
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
3OZ9
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BU of 3oz9 by Molmil
Crystal Structure of anti-gp41 Fab NC-1
Descriptor: Fab NC-1 IgG2a heavy chain, Fab NC-1 kappa light chain, GLYCEROL
Authors:Stanfield, R.L, Calarese, D.A, Jiang, S, Wilson, I.A.
Deposit date:2010-09-24
Release date:2010-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal Structure of anti-gp41 Fab NC-1
TO BE PUBLISHED
2I25
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BU of 2i25 by Molmil
Crystal structure analysis of the nurse shark New antigen Receptor PBLA8 variable domain in complex with lysozyme
Descriptor: Lysozyme C, New Antigen Receptor PBLA8
Authors:Stanfield, R.L, Wilson, I.A.
Deposit date:2006-08-15
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
3F58
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BU of 3f58 by Molmil
IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 12-RESIDUE CYCLIC PEPTIDE (INCLUDING RESIDUES 315-324 OF HIV-1 GP120 (MN ISOLATE); H315S MUTATION
Descriptor: PROTEIN (CYCLIC PEPTIDE (GP120)), PROTEIN (IMMUNOGLOBULIN GAMMA I (58.2))
Authors:Stanfield, R.L, Cabezas, E, Satterthwait, A.C, Stura, E.A, Profy, A.T, Wilson, I.A.
Deposit date:1998-10-23
Release date:1999-02-09
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Dual conformations for the HIV-1 gp120 V3 loop in complexes with different neutralizing fabs.
Structure Fold.Des., 7, 1999
2OJZ
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BU of 2ojz by Molmil
Anti-DNA antibody ED10
Descriptor: Fab ED10 heavy chain, Fab ED10 light chain
Authors:Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
Deposit date:2007-01-15
Release date:2007-06-12
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.73 Å)
Cite:Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2OK0
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BU of 2ok0 by Molmil
Fab ED10-DNA complex
Descriptor: 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain
Authors:Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
Deposit date:2007-01-15
Release date:2007-06-12
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
3T0W
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BU of 3t0w by Molmil
Fluorogen activating protein M8VL in complex with dimethylindole red
Descriptor: 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.501 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3T0X
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BU of 3t0x by Molmil
Fluorogen Activating Protein M8VLA4(S55P) in complex with dimethylindole red
Descriptor: 1,2-ETHANEDIOL, 1-(3-sulfopropyl)-4-[(1E,3E)-3-(1,3,3-trimethyl-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl]quinolinium, Immunoglobulin variable lambda domain M8VLA4(S55P), ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
3T0V
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BU of 3t0v by Molmil
Unliganded fluorogen activating protein M8VL
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
Authors:Stanfield, R, Senutovitch, N, Bhattacharyya, S, Rule, G, Wilson, I.A, Armitage, B, Waggoner, A.S, Berget, P.
Deposit date:2011-07-20
Release date:2012-03-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.451 Å)
Cite:A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red.
Biochemistry, 51, 2012
2B1H
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BU of 2b1h by Molmil
Crystal structure analysis of anti-HIV-1 V3 Fab 2219 in complex with UG29 peptide
Descriptor: Fab 2219, heavy chain, light chain, ...
Authors:Stanfield, R.L, Gorny, M.K, Zolla-Pazner, S, Wilson, I.A.
Deposit date:2005-09-15
Release date:2006-07-04
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human immunodeficiency virus type 1 (HIV-1) neutralizing antibody 2219 in complex with three different V3 peptides reveal a new binding mode for HIV-1 cross-reactivity.
J.Virol., 80, 2006

220472

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