2MNZ
| NMR Structure of KDM5B PHD1 finger in complex with H3K4me0(1-10aa) | Descriptor: | H3K4me0, Lysine-specific demethylase 5B, ZINC ION | Authors: | Zhang, Y, Yang, H.R, Guo, X, Rong, N.Y, Song, Y.J, Xu, Y.W, Lan, W.X, Xu, Y.H, Cao, C. | Deposit date: | 2014-04-16 | Release date: | 2014-08-06 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The PHD1 finger of KDM5B recognizes unmodified H3K4 during the demethylation of histone H3K4me2/3 by KDM5B. Protein Cell, 5, 2014
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1OOT
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1VA7
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3ANN
| Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with quinolin-2-ylmethylphosphonic acid | Descriptor: | (quinolin-2-ylmethyl)phosphonic acid, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Endo, K, Kato, M, Deng, L, Song, Y, Yajima, S. | Deposit date: | 2010-09-03 | Release date: | 2011-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes ACS Med Chem Lett, 2, 2011
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3ANM
| Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with 5-phenylpyridin-2-ylmethylphosphonic acid | Descriptor: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, [(5-phenylpyridin-2-yl)methyl]phosphonic acid | Authors: | Endo, K, Kato, M, Deng, L, Song, Y, Yajima, S. | Deposit date: | 2010-09-03 | Release date: | 2011-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes ACS Med Chem Lett, 2, 2011
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3ANL
| Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with pyridin-2-ylmethylphosphonic acid | Descriptor: | (pyridin-2-ylmethyl)phosphonic acid, 1-deoxy-D-xylulose 5-phosphate reductoisomerase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Endo, K, Kato, M, Deng, L, Song, Y, Yajima, S. | Deposit date: | 2010-09-03 | Release date: | 2011-02-23 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase/Lipophilic Phosphonate Complexes ACS Med Chem Lett, 2, 2011
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2V1R
| Yeast Pex13 SH3 domain complexed with a peptide from Pex14 at 2.1 A resolution | Descriptor: | PEROXISOMAL MEMBRANE PROTEIN PAS20, PEX14 | Authors: | Kursula, I, Kursula, P, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | Deposit date: | 2007-05-29 | Release date: | 2008-06-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Genomics of Yeast SH3 Domains To be Published
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2V1Q
| Atomic-resolution structure of the yeast Sla1 SH3 domain 3 | Descriptor: | CHLORIDE ION, CYTOSKELETON ASSEMBLY CONTROL PROTEIN SLA1, PLATINUM (II) ION, ... | Authors: | Kursula, I, Kursula, P, Zou, P, Lehmann, F, Song, Y.H, Wilmanns, M. | Deposit date: | 2007-05-29 | Release date: | 2008-06-03 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Structural Genomics of Yeast SH3 Domains To be Published
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2VKN
| YEAST SHO1 SH3 DOMAIN COMPLEXED WITH A PEPTIDE FROM PBS2 | Descriptor: | MAP KINASE KINASE PBS2, PROTEIN SSU81, SULFATE ION | Authors: | Kursula, P, Kursula, I, Song, Y.H, Paraskevopoulos, K, Wilmanns, M. | Deposit date: | 2007-12-20 | Release date: | 2008-02-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural Genomics of Yeast SH3 Domains To be Published
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2WL8
| X-ray crystal structure of Pex19p | Descriptor: | PEROXISOMAL BIOGENESIS FACTOR 19 | Authors: | Schueller, N, Holton, S.J, Stanley, W.A, Song, Y.H, Konarev, P, Roessle, M, Erdmann, R, Schliebs, W, Wilmanns, M. | Deposit date: | 2009-06-22 | Release date: | 2010-06-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Peroxisomal Receptor Pex19P Forms a Helical Mpts Recognition Domain. Embo J., 29, 2010
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1WDX
| Yeast BBC1 SH3 domain, triclinic crystal form | Descriptor: | Myosin tail region-interacting protein MTI1 | Authors: | Wilmanns, M, Consani Textor, L, Kursula, P, Kursula, I, Lehmann, F, Song, Y.H. | Deposit date: | 2004-05-19 | Release date: | 2005-05-31 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of Yeast BBC1 SH3 domain, triclinic crystal form To be Published
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6MO1
| Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | Descriptor: | 5-[4-(aminomethyl)phenyl]-6-[4-(furan-3-yl)phenyl]-N-[(piperidin-4-yl)methyl]pyrazin-2-amine, FLAVIVIRUS_NS2B/Peptidase S7 | Authors: | Lin, Y.-L, Hua, Y, Nie, S, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | Deposit date: | 2018-10-03 | Release date: | 2019-05-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J.Am.Chem.Soc., 141, 2019
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6MO0
| Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | Descriptor: | 1-(4-{3-[4-(furan-3-yl)phenyl]-5-[(piperidin-4-yl)methoxy]pyrazin-2-yl}phenyl)methanamine, FLAVIVIRUS_NS2B/Peptidase S7 | Authors: | Lin, Y.-L, Nie, S, Hua, Y, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | Deposit date: | 2018-10-03 | Release date: | 2019-05-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J. Am. Chem. Soc., 141, 2019
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6MO2
| Structure of dengue virus protease with an allosteric Inhibitor that blocks replication | Descriptor: | 1-(4-{5-[(piperidin-4-yl)methoxy]-3-[4-(1H-pyrazol-4-yl)phenyl]pyrazin-2-yl}phenyl)methanamine, FLAVIVIRUS_NS2B/Peptidase S7 | Authors: | Lin, Y.-L, Nie, S, Hua, Y, Wu, J, Wu, F, Huo, T, Yao, Y, Song, Y. | Deposit date: | 2018-10-03 | Release date: | 2019-05-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Discovery, X-ray Crystallography and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease. J.Am.Chem.Soc., 141, 2019
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1YN8
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1YNZ
| SH3 domain of yeast Pin3 | Descriptor: | Pin3p | Authors: | Kursula, P, Kursula, I, Zou, P, Lehmann, F, Song, Y.H, Wilmanns, M. | Deposit date: | 2005-01-26 | Release date: | 2006-05-30 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural analysis of the yeast SH3 domain proteome To be Published
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1ZUK
| Yeast BBC1 Sh3 domain complexed with a peptide from Las17 | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Myosin tail region-interacting protein MTI1, ... | Authors: | Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | Deposit date: | 2005-05-31 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural genomics of yeast SH3 domains To be Published
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1ZUU
| Crystal structure of the yeast Bzz1 first SH3 domain at 0.97-A resolution | Descriptor: | BZZ1 protein, MAGNESIUM ION, UNKNOWN ATOM OR ION | Authors: | Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | Deposit date: | 2005-06-01 | Release date: | 2006-09-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Structural genomics of yeast SH3 domains To be Published
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1ZX6
| High-resolution crystal structure of yeast Pin3 SH3 domain | Descriptor: | Ypr154wp | Authors: | Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | Deposit date: | 2005-06-07 | Release date: | 2006-10-24 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural genomics of yeast SH3 domains To be Published
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3SR4
| Crystal Structure of Human DOT1L in Complex with a Selective Inhibitor | Descriptor: | (2S)-2-azanyl-4-[[(2S,3S,4R,5R)-5-[6-(methylamino)purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]butanoic acid, ACETATE ION, GLYCEROL, ... | Authors: | Diao, J, Chen, P, Yao, Y, Prasad, B.V.V, Song, Y. | Deposit date: | 2011-07-06 | Release date: | 2011-10-05 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies. J.Am.Chem.Soc., 133, 2011
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2A08
| Structure of the yeast YHH6 SH3 domain | Descriptor: | Hypothetical 41.8 kDa protein in SPO13-ARG4 intergenic region | Authors: | Kursula, P, Kursula, I, Song, Y.H, Lehmann, F, Zou, P, Wilmanns, M. | Deposit date: | 2005-06-16 | Release date: | 2006-06-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | 3-D proteome of yeast SH3 domains To be Published
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2A28
| Atomic-resolution crystal structure of the second SH3 domain of yeast Bzz1 determined from a pseudomerohedrally twinned crystal | Descriptor: | BZZ1 protein | Authors: | Kursula, P, Kursula, I, Lehmann, F, Zou, P, Song, Y.H, Wilmanns, M. | Deposit date: | 2005-06-22 | Release date: | 2006-09-12 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Structural genomics of yeast SH3 domains To be Published
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3FAV
| Structure of the CFP10-ESAT6 complex from Mycobacterium tuberculosis | Descriptor: | 6 kDa early secretory antigenic target, ESAT-6-like protein esxB, IMIDAZOLE, ... | Authors: | Poulsen, C, Holton, S.J, Wilmanns, M, Song, Y.H. | Deposit date: | 2008-11-18 | Release date: | 2009-11-24 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | WXG100 protein superfamily consists of three subfamilies and exhibits an alpha-helical C-terminal conserved residue pattern. Plos One, 9, 2014
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3RAS
| Crystal structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) complexed with a lipophilic phosphonate inhibitor | Descriptor: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, 3-(N-HYDROXYACETAMIDO)-1-(3,4-DICHLOROPHENYL)PROPYLPHOSPHONIC ACID, MANGANESE (II) ION, ... | Authors: | Diao, J, Deng, L, Prasad, B.V.V, Song, Y. | Deposit date: | 2011-03-28 | Release date: | 2011-05-25 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies. J.Med.Chem., 54, 2011
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3GWK
| Structure of the homodimeric WXG-100 family protein from Streptococcus agalactiae | Descriptor: | Putative uncharacterized protein SAG1039, SULFATE ION | Authors: | Poulsen, C, Gries, F, Wilmanns, M, Song, Y.H. | Deposit date: | 2009-04-01 | Release date: | 2010-09-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | WXG100 protein superfamily consists of three subfamilies and exhibits an alpha-helical C-terminal conserved residue pattern. Plos One, 9, 2014
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