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PDB: 24 results

7QI6
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BU of 7qi6 by Molmil
Human mitochondrial ribosome in complex with mRNA, A/P- and P/E-tRNAs at 2.98 A resolution
Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ...
Authors:Singh, V, Itoh, Y, Amunts, A.
Deposit date:2021-12-14
Release date:2023-05-17
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Nat Commun, 15, 2024
7QI5
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BU of 7qi5 by Molmil
Human mitochondrial ribosome in complex with mRNA, A/A-, P/P- and E/E-tRNAs at 2.63 A resolution
Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ...
Authors:Singh, V, Itoh, Y, Amunts, A.
Deposit date:2021-12-14
Release date:2023-07-05
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Nat Commun, 15, 2024
7QI4
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BU of 7qi4 by Molmil
Human mitochondrial ribosome at 2.2 A resolution (bound to partly built tRNAs and mRNA)
Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ...
Authors:Singh, V, Itoh, Y, Amunts, A.
Deposit date:2021-12-14
Release date:2022-07-13
Last modified:2024-07-31
Method:ELECTRON MICROSCOPY (2.21 Å)
Cite:Mitoribosome structure with cofactors and modifications reveals mechanism of ligand binding and interactions with L1 stalk.
Nat Commun, 15, 2024
5X4B
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BU of 5x4b by Molmil
Crystal Structure of N-terminal G-domain of EngA from Bacillus subtilis
Descriptor: GTPase Der, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Singh, V, Prakash, B.
Deposit date:2017-02-11
Release date:2017-05-31
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal Structure of N-terminal G-domain of EngA from Bacillus subtilis
To Be Published
8ANY
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BU of 8any by Molmil
Human mitochondrial ribosome in complex with LRPPRC, SLIRP, A-site, P-site, E-site tRNAs and mRNA
Descriptor: 1,4-DIAMINOBUTANE, 12S mitochondrial rRNA, 16S mitochondrial rRNA, ...
Authors:Singh, V, Itoh, Y, Amunts, A.
Deposit date:2022-08-06
Release date:2023-08-16
Last modified:2024-09-04
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Structural basis of LRPPRC-SLIRP-dependent translation by the mitoribosome.
Nat.Struct.Mol.Biol., 2024
6ZSC
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BU of 6zsc by Molmil
Human mitochondrial ribosome in complex with E-site tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-09-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
8E7E
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BU of 8e7e by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Afrin, S, Saelices, L.
Deposit date:2022-08-23
Release date:2023-08-30
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (3.61 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8TDO
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BU of 8tdo by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, variant-type morphology
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Saelices, L.
Deposit date:2023-07-04
Release date:2023-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
8TDN
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BU of 8tdn by Molmil
Cryo-EM structure of cardiac amyloid fibril from a variant ATTR I84S amyloidosis patient-3, wild-type morphology
Descriptor: Transthyretin
Authors:Nguyen, B.A, Singh, V, Saelices, L.
Deposit date:2023-07-04
Release date:2023-12-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural polymorphism of amyloid fibrils in ATTR amyloidosis revealed by cryo-electron microscopy.
Nat Commun, 15, 2024
7P2E
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BU of 7p2e by Molmil
Human mitochondrial ribosome small subunit in complex with IF3, GMPPMP and streptomycin
Descriptor: 12S mitochondrial rRNA, 28S ribosomal protein S10, mitochondrial, ...
Authors:Itoh, Y, Khawaja, A, Singh, V, Rorbach, J, Amunts, A.
Deposit date:2021-07-05
Release date:2022-07-27
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure of the mitoribosomal small subunit with streptomycin reveals Fe-S clusters and physiological molecules.
Elife, 11, 2022
4G1P
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BU of 4g1p by Molmil
Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccharomyces cerevisiae
Descriptor: CYSTEINE, Cys-Gly metallodipeptidase DUG1, GLYCINE, ...
Authors:Singh, A.K, Singh, M, Pandya, V.K, Singh, V, Mittal, M, Kumaran, S.
Deposit date:2012-07-11
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.547 Å)
Cite:Structural and Mechanistic Basis of Substrate Recognition by Novel Di-peptidase Dug1p From Saccromyces cerevesiae
To be published
7OG4
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BU of 7og4 by Molmil
Human mitochondrial ribosome in complex with P/E-tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2021-05-06
Release date:2021-06-23
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
1Y6R
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BU of 1y6r by Molmil
Crystal structure of MTA/AdoHcy nucleosidase complexed with MT-ImmA.
Descriptor: (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, MTA/SAH nucleosidase
Authors:Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L.
Deposit date:2004-12-06
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
J.Biol.Chem., 280, 2005
6ZSE
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BU of 6zse by Molmil
Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-09-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZSB
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BU of 6zsb by Molmil
Human mitochondrial ribosome in complex with mRNA and P-site tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-09-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZSG
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BU of 6zsg by Molmil
Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-10-14
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZSA
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BU of 6zsa by Molmil
Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-10-21
Last modified:2024-05-01
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZSD
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BU of 6zsd by Molmil
Human mitochondrial ribosome in complex with mRNA, P-site tRNA and E-site tRNA
Descriptor: 12S mitochondrial rRNA, 16S mitochondrial rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-09-16
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
6ZS9
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BU of 6zs9 by Molmil
Human mitochondrial ribosome in complex with ribosome recycling factor
Descriptor: 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ...
Authors:Aibara, S, Singh, V, Modelska, A, Amunts, A.
Deposit date:2020-07-15
Release date:2020-10-14
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of mitochondrial translation.
Elife, 9, 2020
1Y6Q
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BU of 1y6q by Molmil
Cyrstal structure of MTA/AdoHcy nucleosidase complexed with MT-DADMe-ImmA
Descriptor: (3R,4S)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]-4-[(METHYLSULFANYL)METHYL]PYRROLIDIN-3-OL, CHLORIDE ION, MTA/SAH nucleosidase
Authors:Lee, J.E, Singh, V, Evans, G.B, Tyler, P.C, Furneaux, R.H, Cornell, K.A, Riscoe, M.K, Schramm, V.L, Howell, P.L.
Deposit date:2004-12-06
Release date:2005-03-01
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
J.Biol.Chem., 280, 2005
4G12
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BU of 4g12 by Molmil
Crystal structure of putative TetR family transcriptional regulator, Fad35R, from Mycobacterium tuberculosis
Descriptor: GLYCEROL, Probable transcriptional regulatory protein (Probably TETR-FAMILY)
Authors:Singh, A.K, Manjasetty, B.A, Singh, V, Mittal, M, Kumaran, S.
Deposit date:2012-07-10
Release date:2013-07-10
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:Crystal structure of putative TetR family transcriptional regulator, Fad35R, from Mycobacterium tuberculosis
to be published
1K27
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BU of 1k27 by Molmil
Crystal Structure of 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with a Transition State Analogue
Descriptor: (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5'-Deoxy-5'-Methylthioadenosine Phosphorylase, PHOSPHATE ION
Authors:Shi, W, Singh, V, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L.
Deposit date:2001-09-26
Release date:2003-09-30
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A
Biochemistry, 43, 2004
1ZOS
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BU of 1zos by Molmil
Structure of 5'-methylthionadenosine/S-Adenosylhomocysteine nucleosidase from S. pneumoniae with a transition-state inhibitor MT-ImmA
Descriptor: (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL, 5'-methylthioadenosine / S-adenosylhomocysteine nucleosidase
Authors:Shi, W, Singh, V, Zhen, R, Tyler, P.C, Furneaux, R.H, Almo, S.C, Schramm, V.L.
Deposit date:2005-05-13
Release date:2006-04-25
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae.
Biochemistry, 45, 2006
1U5W
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BU of 1u5w by Molmil
Crystal structure of hypothetical protein yjjX from Escherichia coli
Descriptor: Hypothetical UPF0244 protein yjjX, SULFATE ION
Authors:Zheng, J, Singh, V.K, Jia, Z, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI)
Deposit date:2004-07-28
Release date:2005-08-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of an ITPase/XTPase in Escherichia coli by Structural and Biochemical Analysis
Structure, 13, 2005

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