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PDB: 63 results

4KF7
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BU of 4kf7 by Molmil
Nup188(aa1-1160) from Myceliophthora thermophila
Descriptor: Nup188
Authors:Schwartz, T.U, Andersen, K.R.
Deposit date:2013-04-26
Release date:2013-06-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors.
Elife, 2, 2013
4KF8
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BU of 4kf8 by Molmil
Nup188(aa1445-1827) from Myceliophthora thermophila
Descriptor: Nup188
Authors:Schwartz, T.U, Andersen, K.R.
Deposit date:2013-04-26
Release date:2013-06-19
Last modified:2013-08-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors.
Elife, 2, 2013
4TVS
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BU of 4tvs by Molmil
LAP1(aa356-583), H.sapiens, bound to VHH-BS1
Descriptor: GLYCEROL, SULFATE ION, Torsin-1A-interacting protein 1, ...
Authors:Sosa, B.A, Schwartz, T.U.
Deposit date:2014-06-27
Release date:2014-09-03
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:How lamina-associated polypeptide 1 (LAP1) activates Torsin.
Elife, 3, 2014
3MZL
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BU of 3mzl by Molmil
Sec13/Sec31 edge element, loop deletion mutant
Descriptor: Protein transport protein SEC13, Protein transport protein SEC31
Authors:Whittle, J.R, Schwartz, T.U.
Deposit date:2010-05-12
Release date:2010-08-18
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of the Sec13-Sec16 edge element, a template for assembly of the COPII vesicle coat.
J.Cell Biol., 190, 2010
1XKS
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The crystal structure of the N-terminal domain of Nup133 reveals a beta-propeller fold common to several nucleoporins
Descriptor: Nuclear pore complex protein Nup133
Authors:Berke, I.C, Boehmer, T, Blobel, G, Schwartz, T.U.
Deposit date:2004-09-29
Release date:2004-12-07
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural and functional analysis of Nup133 domains reveals modular building blocks of the nuclear pore complex.
J.Cell Biol., 167, 2004
2QX5
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BU of 2qx5 by Molmil
Structure of nucleoporin Nic96
Descriptor: CHLORIDE ION, Nucleoporin NIC96
Authors:Jeudy, S, Schwartz, T.U.
Deposit date:2007-08-10
Release date:2007-09-25
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of nucleoporin Nic96 reveals a novel, intricate helical domain architecture
J.Biol.Chem., 282, 2007
2GED
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BU of 2ged by Molmil
Signal Recognition Particle Receptor Beta-Subunit in nucleotide-free dimerized form
Descriptor: SULFATE ION, Signal recognition particle receptor beta subunit
Authors:Schmidt, D, Schwartz, T.U.
Deposit date:2006-03-19
Release date:2006-04-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Homodimerization of the G protein SR{beta} in the nucleotide-free state involves proline cis/trans isomerization in the switch II region.
Proc.Natl.Acad.Sci.USA, 103, 2006
6OIF
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BU of 6oif by Molmil
Cryo-EM structure of human TorsinA filament
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Torsin-1A
Authors:Zheng, W, Demircioglu, F.E, Schwartz, T.U, Egelman, E.H.
Deposit date:2019-04-09
Release date:2019-07-24
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn.
Nat Commun, 10, 2019
5T0N
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BU of 5t0n by Molmil
Pseudo-apo structure of Sestrin2 at 3.0 angstrom resolution
Descriptor: LEUCINE, Sestrin-2
Authors:Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2016-08-16
Release date:2016-10-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.004 Å)
Cite:The apo-structure of the leucine sensor Sestrin2 is still elusive.
Sci.Signal., 9, 2016
7TJC
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VHH Chl-B2 in complex with Chloramphenicol
Descriptor: CHLORAMPHENICOL, GLYCEROL, VHH-Chl-B2
Authors:Nordeen, S.A, Schwartz, T.U.
Deposit date:2022-01-16
Release date:2022-11-23
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure and specificity of an anti-chloramphenicol single domain antibody for detection of amphenicol residues.
Protein Sci., 31, 2022
5DJ4
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Leucine-bound Sestrin2 from Homo sapiens
Descriptor: LEUCINE, Sestrin-2
Authors:Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2015-09-01
Release date:2015-11-25
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.697 Å)
Cite:Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway.
Science, 351, 2016
5I2C
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BU of 5i2c by Molmil
Arginine-bound CASTOR1 from Homo sapiens
Descriptor: ACETATE ION, ARGININE, GATS-like protein 3
Authors:Saxton, R.A, Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2016-02-08
Release date:2016-08-10
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.
Nature, 536, 2016
7PER
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BU of 7per by Molmil
Model of the inner ring of the human nuclear pore complex
Descriptor: Nuclear pore complex protein Nup155, Nuclear pore complex protein Nup205, Nuclear pore complex protein Nup93, ...
Authors:Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U.
Deposit date:2021-08-11
Release date:2021-10-20
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
7PEQ
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Model of the outer rings of the human nuclear pore complex
Descriptor: Nuclear pore complex protein Nup107, Nuclear pore complex protein Nup133, Nuclear pore complex protein Nup160, ...
Authors:Schuller, A.P, Wojtynek, M, Mankus, D, Tatli, M, Kronenberg-Tenga, R, Regmi, S.G, Dasso, M, Weis, K, Medalia, O, Schwartz, T.U.
Deposit date:2021-08-11
Release date:2021-10-20
Last modified:2021-11-24
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The cellular environment shapes the nuclear pore complex architecture.
Nature, 598, 2021
5TJW
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BU of 5tjw by Molmil
Influenza A virus Nucleoprotein in Complex with Inhibitory Nanobody
Descriptor: NP-specific inhibitory VHH, Nucleoprotein
Authors:Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U.
Deposit date:2016-10-05
Release date:2016-12-21
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.231 Å)
Cite:The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment.
MBio, 7, 2016
5UKB
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BU of 5ukb by Molmil
VSV N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1004
Descriptor: Anti-vesicular stomatitis virus N VHH, Nucleocapsid, RNA (45-MER)
Authors:Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U.
Deposit date:2017-01-20
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (5.473 Å)
Cite:Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
EMBO Rep., 18, 2017
5UK4
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BU of 5uk4 by Molmil
VESICULAR STOMATITS VIRUS N PROTEIN IN COMPLEX WITH INHIBITORY NANOBODY 1307
Descriptor: Anti-vesicular stomatitis virus N VHH, Nucleoprotein, RNA (45-MER)
Authors:Hanke, L, Knockenhauer, K.E, Ploegh, H.L, Schwartz, T.U.
Deposit date:2017-01-19
Release date:2017-04-19
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.204 Å)
Cite:Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.
EMBO Rep., 18, 2017
5J1S
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BU of 5j1s by Molmil
TorsinA-LULL1 complex, H. sapiens, bound to VHH-BS2
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Demircioglu, F.E, Schwartz, T.U.
Deposit date:2016-03-29
Release date:2016-08-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.
Elife, 5, 2016
5JJ7
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BU of 5jj7 by Molmil
Fic-1 (aa134 - 508 E274G) from C. elegans
Descriptor: Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION
Authors:Cruz, V.E, Schwartz, T.U.
Deposit date:2016-04-22
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.749 Å)
Cite:Fic-1 (aa134 - 508 E274G) from C. elegans
To be published
5J1T
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BU of 5j1t by Molmil
TorsinAdeltaE-LULL1 complex, H. sapiens, bound to VHH-BS2
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, CHLORIDE ION, ...
Authors:Demircioglu, F.E, Schwartz, T.U.
Deposit date:2016-03-29
Release date:2016-08-17
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.402 Å)
Cite:Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.
Elife, 5, 2016
5JJ6
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BU of 5jj6 by Molmil
Fic-1 (aa134 - 508) from C. elegans
Descriptor: Adenosine monophosphate-protein transferase FICD homolog, SULFATE ION
Authors:Cruz, V.E, Schwartz, T.U.
Deposit date:2016-04-22
Release date:2016-06-01
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.907 Å)
Cite:Fic-1 dimer
To be published
4I0O
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BU of 4i0o by Molmil
Nucleoporin ELYS (aa1-494), Mus musculus
Descriptor: Protein ELYS
Authors:Bilokapic, S, Schwartz, T.U.
Deposit date:2012-11-17
Release date:2013-04-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Functional Studies of the 252 kDa Nucleoporin ELYS Reveal Distinct Roles for Its Three Tethered Domains.
Structure, 21, 2013
4YD8
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BU of 4yd8 by Molmil
Bardet-Biedl Syndrome 9 Protein (aa1-407), Homo sapiens
Descriptor: Protein PTHB1
Authors:Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2015-02-21
Release date:2015-06-24
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Characterization of Bardet-Biedl Syndrome 9 Protein (BBS9).
J.Biol.Chem., 290, 2015
4YGA
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BU of 4yga by Molmil
CDPK1, from Toxoplasma gondii, bound to inhibitory VHH-1B7
Descriptor: CALCIUM ION, Calmodulin-domain protein kinase 1, VHH-1B7
Authors:Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2015-02-26
Release date:2015-08-26
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.94 Å)
Cite:Allosteric activation of apicomplexan calcium-dependent protein kinases.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YCZ
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BU of 4ycz by Molmil
Y-COMPLEX HUB (NUP85-NUP120-NUP145C-SEC13 COMPLEX) FROM M. THERMOPHILA (A.K.A. T. HETEROTHALLICA)
Descriptor: Fusion Protein of Sec13 and Nup145C, Nup120, Nup85
Authors:Kelley, K, Knockenhauer, K.E, Schwartz, T.U.
Deposit date:2015-02-20
Release date:2015-04-01
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Atomic structure of the Y complex of the nuclear pore.
Nat.Struct.Mol.Biol., 22, 2015

 

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