8QYN
 
 | | Human 20S proteasome assembly intermediate structure 5 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
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8QYO
 | | Human proteasome 20S core particle | | Descriptor: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.84 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
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8QYL
 | | Human 20S proteasome assembly intermediate structure 2 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.67 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
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8QYM
 | | Human 20S proteasome assembly intermediate structure 3 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
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8QZ9
 | | Human 20S proteasome assembly intermediate structure 4 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.95 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
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8QYS
 | | Human preholo proteasome 20S core particle | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome maturation protein, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
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8QYJ
 | | Human 20S proteasome assembly structure 1 | | Descriptor: | Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ... | | Authors: | Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A. | | Deposit date: | 2023-10-26 | | Release date: | 2024-02-21 | | Last modified: | 2024-04-17 | | Method: | ELECTRON MICROSCOPY (2.73 Å) | | Cite: | Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 2024
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1FQV
 | | Insights into scf ubiquitin ligases from the structure of the skp1-skp2 complex | | Descriptor: | SKP1, SKP2 | | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | | Deposit date: | 2000-09-06 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
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1FS2
 | | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | | Descriptor: | SKP1, SKP2 | | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | | Deposit date: | 2000-09-08 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
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1FS1
 | | INSIGHTS INTO SCF UBIQUITIN LIGASES FROM THE STRUCTURE OF THE SKP1-SKP2 COMPLEX | | Descriptor: | CYCLIN A/CDK2-ASSOCIATED P19, CYCLIN A/CDK2-ASSOCIATED P45 | | Authors: | Schulman, B.A, Carrano, A.C, Jeffrey, P.D, Bowen, Z, Kinnucan, E.R.E, Finnin, M.S, Elledge, S.J, Harper, J.W, Pagano, M, Pavletich, N.P. | | Deposit date: | 2000-09-08 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Nature, 408, 2000
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3IVQ
 | | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-CiSBC2 | | Descriptor: | CiSBC2, Speckle-type POZ protein | | Authors: | Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S. | | Deposit date: | 2009-09-01 | | Release date: | 2009-10-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
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3IVV
 | | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-PucSBC1_pep1 | | Descriptor: | PucSBC1, Speckle-type POZ protein | | Authors: | Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S. | | Deposit date: | 2009-09-01 | | Release date: | 2009-10-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.25 Å) | | Cite: | Structures of SPOP-Substrate Complexes: Insights into Molecular Architectures of BTB-Cul3 Ubiquitin Ligases.
Mol.Cell, 36, 2009
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3IVB
 | | Structures of SPOP-Substrate Complexes: Insights into Architectures of BTB-Cul3 Ubiquitin Ligases: SPOPMATH-MacroH2ASBCpep1 | | Descriptor: | CHLORIDE ION, Core histone macro-H2A.1, Speckle-type POZ protein, ... | | Authors: | Schulman, B.A, Miller, D.J, Calabrese, M.F, Seyedin, S. | | Deposit date: | 2009-08-31 | | Release date: | 2009-10-20 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Structure 9
To be Published
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7WUG
 | | GID subcomplex: Gid12 bound Substrate Receptor Scaffolding module | | Descriptor: | Glucose-induced degradation protein 8, HLJ1_G0042170.mRNA.1.CDS.1, Vacuolar import and degradation protein 24, ... | | Authors: | Qiao, S, Cheng, J.D, Schulman, B.A. | | Deposit date: | 2022-02-08 | | Release date: | 2022-06-08 | | Last modified: | 2022-06-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation.
Nat Commun, 13, 2022
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7Q51
 | | yeast Gid10 bound to a Phe/N-peptide | | Descriptor: | CHLORIDE ION, FWLPANLW peptide, Uncharacterized protein YGR066C | | Authors: | Chrustowicz, J, Sherpa, D, Prabu, J.R, Schulman, B.A. | | Deposit date: | 2021-11-02 | | Release date: | 2022-03-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.22 Å) | | Cite: | Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022
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7Q50
 | | human Gid4 bound to a Phe/N-peptide | | Descriptor: | FDVSWFMG peptide, Glucose-induced degradation protein 4 homolog | | Authors: | Chrustowicz, J, Sherpa, D, Loke, M.S, Prabu, J.R, Schulman, B.A. | | Deposit date: | 2021-11-02 | | Release date: | 2022-03-02 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.16 Å) | | Cite: | Multifaceted N-Degron Recognition and Ubiquitylation by GID/CTLH E3 Ligases.
J.Mol.Biol., 434, 2022
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7Q4Y
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7QQY
 | | yeast Gid10 bound to Art2 Pro/N-degron | | Descriptor: | CHLORIDE ION, ECM21, Uncharacterized protein YGR066C | | Authors: | Chrustowicz, J, Sherpa, D, Schulman, B.A. | | Deposit date: | 2022-01-10 | | Release date: | 2022-03-09 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.26 Å) | | Cite: | A GID E3 ligase assembly ubiquitinates an Rsp5 E3 adaptor and regulates plasma membrane transporters.
Embo Rep., 23, 2022
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7Z8B
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7Z8T
 | | CAND1-SCF-SKP2 CAND1 engaged SCF rocked | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-18 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
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7Z8R
 | | CAND1-CUL1-RBX1 | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-18 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
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7ZBZ
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7ZBW
 | | CAND1-SCF-SKP2 CAND1 rolling-2 SCF engaged | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-24 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
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7Z8V
 | | CAND1-SCF-SKP2 (SKP1deldel) CAND1 engaged SCF rocked | | Descriptor: | Cullin-1, Cullin-associated NEDD8-dissociated protein 1, E3 ubiquitin-protein ligase RBX1, ... | | Authors: | Baek, K, Schulman, B.A. | | Deposit date: | 2022-03-18 | | Release date: | 2023-04-19 | | Last modified: | 2023-05-10 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Systemwide disassembly and assembly of SCF ubiquitin ligase complexes.
Cell, 186, 2023
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6WY6
 | | Crystal structure of S. cerevisiae Atg8 in complex with Ede1 (1220-1247) | | Descriptor: | Autophagy-related protein 8, EH domain-containing and endocytosis protein 1 | | Authors: | Zheng, Y, Wilfling, F, Baumeister, W, Schulman, B.A. | | Deposit date: | 2020-05-12 | | Release date: | 2020-12-02 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (1.773 Å) | | Cite: | A Selective Autophagy Pathway for Phase-Separated Endocytic Protein Deposits.
Mol.Cell, 80, 2020
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