365D
| STRUCTURAL BASIS FOR G C RECOGNITION IN THE DNA MINOR GROOVE | Descriptor: | DNA (5'-D(*CP*CP*AP*GP*GP*(CBR)P*CP*TP*GP*G)-3'), IMIDAZOLE-PYRROLE POLYAMIDE | Authors: | Kielkopf, C.L, Baird, E.E, Dervan, P.B, Rees, D.C. | Deposit date: | 1997-12-17 | Release date: | 1998-02-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for G.C recognition in the DNA minor groove. Nat.Struct.Biol., 5, 1998
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2NIP
| NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII | Descriptor: | IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN | Authors: | Komiya, H, Georgiadis, M.M, Chakrabarti, P, Woo, D, Kornuc, J.J, Rees, D.C. | Deposit date: | 1998-05-11 | Release date: | 1998-11-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformational variability in structures of the nitrogenase iron proteins from Azotobacter vinelandii and Clostridium pasteurianum. J.Mol.Biol., 280, 1998
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2CXB
| CRYSTALLIZATION AND X-RAY STRUCTURE DETERMINATION OF CYTOCHROME C2 FROM RHODOBACTER SPHAEROIDES IN THREE CRYSTAL FORMS | Descriptor: | CYTOCHROME C2, HEME C | Authors: | Axelrod, H.L, Feher, G, Allen, J.P, Chirino, A.J, Day, M.W, Hsu, B.T, Rees, D.C. | Deposit date: | 1994-04-21 | Release date: | 1995-10-15 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystallization and X-ray structure determination of cytochrome c2 from Rhodobacter sphaeroides in three crystal forms. Acta Crystallogr.,Sect.D, 50, 1994
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3HZQ
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5VPW
| Nitrogenase Cp1 at pH 5 | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (II) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Morrison, C.N, Spatzal, T, Rees, D.C. | Deposit date: | 2017-05-05 | Release date: | 2017-07-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Reversible Protonated Resting State of the Nitrogenase Active Site. J. Am. Chem. Soc., 139, 2017
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5VQ4
| Nitrogenase Av1 at pH 5 | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (III) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Morrison, C.N, Spatzal, T, Rees, D.C. | Deposit date: | 2017-05-07 | Release date: | 2017-07-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Reversible Protonated Resting State of the Nitrogenase Active Site. J. Am. Chem. Soc., 139, 2017
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5VQ3
| Nitrogenase Cp1 at pH 6.5 | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, FE (II) ION, FE(8)-S(7) CLUSTER, ... | Authors: | Morrison, C.N, Spatzal, T, Rees, D.C. | Deposit date: | 2017-05-07 | Release date: | 2017-07-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | Reversible Protonated Resting State of the Nitrogenase Active Site. J. Am. Chem. Soc., 139, 2017
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2AFI
| Crystal Structure of MgADP bound Av2-Av1 Complex | Descriptor: | 3-HYDROXY-3-CARBOXY-ADIPIC ACID, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | Authors: | Tezcan, F.A, Kaiser, J.T, Mustafi, D, Walton, M.Y, Howard, J.B, Rees, D.C. | Deposit date: | 2005-07-25 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Nitrogenase Complexes: Multiple Docking Sites for a Nucleotide Switch Protein Science, 309, 2005
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2C7H
| Solution NMR structure of the DWNN domain from human RBBP6 | Descriptor: | RETINOBLASTOMA-BINDING PROTEIN 6, ISOFORM 3 | Authors: | Pugh, D.J.R, Ab, E, Faro, A, Lutya, P.T, Hoffmann, E, Rees, D.J.G. | Deposit date: | 2005-11-24 | Release date: | 2006-01-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Dwnn, a Novel Ubiquitin-Like Domain, Implicates Rbbp6 in Mrna Processing and Ubiquitin-Like Pathways Bmc Struct.Biol., 6, 2006
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2AFH
| Crystal Structure of Nucleotide-Free Av2-Av1 Complex | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXY-3-CARBOXY-ADIPIC ACID, CALCIUM ION, ... | Authors: | Tezcan, F.A, Kaiser, J.T, Mustafi, D, Walton, M.Y, Howard, J.B, Rees, D.C. | Deposit date: | 2005-07-25 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Nitrogenase Complexes: Multiple Docking Sites for a Nucleotide Switch Protein Science, 309, 2005
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3TG0
| E. coli alkaline phosphatase with bound inorganic phosphate | Descriptor: | Alkaline phosphatase, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Bobyr, E, Lassila, J.K, Wiersma-Koch, H.I, Fenn, T.D, Lee, J.J, Nikolic-Hughes, I, Hodgson, K.O, Rees, D.C, Hedman, B, Herschlag, D. | Deposit date: | 2011-08-16 | Release date: | 2011-11-09 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | High-resolution analysis of Zn(2+) coordination in the alkaline phosphatase superfamily by EXAFS and x-ray crystallography. J.Mol.Biol., 415, 2012
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4AUA
| Liganded X-ray crystal structure of cyclin dependent kinase 6 (CDK6) | Descriptor: | 1H-benzimidazol-2-yl(1H-pyrrol-2-yl)methanone, CYCLIN-DEPENDENT KINASE 6 | Authors: | Cho, Y.S, Angove, H, Brain, C, Chen, C.H.T, Cheng, R, Chopra, R, Chung, K, Congreve, M, Dagostin, C, Davis, D, Feltell, R, Giraldes, J, Hiscock, S, Kim, S, Kovats, S, Lagu, B, Lewry, K, Loo, A, Lu, Y, Luzzio, M, Maniara, W, Mcmenamin, R, Mortenson, P, Benning, R, O'Reilly, M, Rees, D, Shen, J, Smith, T, Wang, Y, Williams, G, Woolford, A, Wrona, W, Xu, M, Yang, F, Howard, S. | Deposit date: | 2012-05-15 | Release date: | 2013-02-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | Fragment-Based Discovery of 7-Azabenzimidazoles as Potent, Highly Selective, and Orally Active CDK4/6 Inhibitors. ACS Med Chem Lett, 3, 2012
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3TUI
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4D2W
| Structure of MELK in complex with inhibitors | Descriptor: | 4-bromo-N-(2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)benzamide, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | Authors: | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | Deposit date: | 2014-05-13 | Release date: | 2014-10-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Acs Med.Chem.Lett., 6, 2015
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4D2P
| Structure of MELK in complex with inhibitors | Descriptor: | 7-({4-[(3-hydroxy-5-methoxyphenyl)amino]benzoyl}amino)-1,2,3,4-tetrahydroisoquinolinium, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | Authors: | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | Deposit date: | 2014-05-12 | Release date: | 2014-10-08 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Acs Med.Chem.Lett., 6, 2015
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1WOD
| CRYSTAL STRUCTURE OF MODA, A MOLYBDATE PROTEIN, COMPLEXED WITH TUNGSTATE | Descriptor: | MODA, TUNGSTATE(VI)ION | Authors: | Hu, Y, Rech, S, Gunsalus, R.P, Rees, D.C. | Deposit date: | 1997-06-17 | Release date: | 1997-12-17 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structure of the molybdate binding protein ModA. Nat.Struct.Biol., 4, 1997
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2NQ2
| An inward-facing conformation of a putative metal-chelate type ABC transporter. | Descriptor: | Hypothetical ABC transporter ATP-binding protein HI1470, Hypothetical ABC transporter permease protein HI1471 | Authors: | Pinkett, H.P, Lee, A.T, Lum, P, Locher, K.P, Rees, D.C. | Deposit date: | 2006-10-30 | Release date: | 2007-01-02 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | An inward-facing conformation of a putative metal-chelate-type ABC transporter. Science, 315, 2007
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3DHX
| Crystal structure of isolated C2 domain of the methionine uptake transporter | Descriptor: | IODIDE ION, Methionine import ATP-binding protein metN | Authors: | Johnson, E, Kaiser, J.T, Lee, A.T, Rees, D.C. | Deposit date: | 2008-06-18 | Release date: | 2008-08-05 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The high-affinity E. coli methionine ABC transporter: structure and allosteric regulation. Science, 321, 2008
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3PDI
| Precursor bound NifEN | Descriptor: | IRON/SULFUR CLUSTER, L-Cluster (Fe8S9), Nitrogenase MoFe cofactor biosynthesis protein NifE, ... | Authors: | Kaiser, J.T, Hu, Y, Wiig, J.A, Rees, D.C, Ribbe, M.W. | Deposit date: | 2010-10-22 | Release date: | 2011-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Precursor-Bound NifEN: A Nitrogenase FeMo Cofactor Maturase/Insertase. Science, 331, 2011
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4D2V
| Structure of MELK in complex with inhibitors | Descriptor: | 7-{[2-methoxy-4-(1H-pyrazol-4-yl)benzoyl]amino}-2,3,4,5-tetrahydro-1H-3-benzazepinium, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | Authors: | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | Deposit date: | 2014-05-13 | Release date: | 2014-10-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Acs Med.Chem.Lett., 6, 2015
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4D2T
| Structure of MELK in complex with inhibitors | Descriptor: | 3-[2-(phenylcarbamoyl)-5-(1H-pyrazol-4-yl)phenoxy]propan-1-aminium, MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE | Authors: | Johnson, C.N, Berdini, V, Beke, L, Bonnet, P, Brehmer, D, Coyle, J.E, Day, P.J, Frederickson, M, Freyne, E.J.E, Gilissen, R.A.H.J, Hamlett, C.C.F, Howard, S, Meerpoel, L, McMenamin, R, Patel, S, Rees, D.C, Sharff, A, Sommen, F, Wu, T, Linders, J.T.M. | Deposit date: | 2014-05-13 | Release date: | 2014-10-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Fragment-Based Discovery of Type I Inhibitors of Maternal Embryonic Leucine Zipper Kinase Acs Med.Chem.Lett., 6, 2015
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6CVL
| Crystal structure of the Escherichia coli ATPgS-bound MetNI methionine ABC transporter in complex with its MetQ binding protein | Descriptor: | IODIDE ION, MERCURY (II) ION, MetI transmembrane subunit, ... | Authors: | Nguyen, P.T, Kaiser, J.T, Rees, D.C. | Deposit date: | 2018-03-28 | Release date: | 2018-11-14 | Last modified: | 2022-04-27 | Method: | X-RAY DIFFRACTION (2.953 Å) | Cite: | Noncanonical role for the binding protein in substrate uptake by the MetNI methionine ATP Binding Cassette (ABC) transporter. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6DZX
| Crystal structure of the N. meningitides methionine-binding protein in its D-methionine bound conformation. | Descriptor: | D-METHIONINE, Lipoprotein | Authors: | Nguyen, P.T, Lai, J.Y, Kaiser, J.T, Rees, D.C. | Deposit date: | 2018-07-05 | Release date: | 2019-07-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.678 Å) | Cite: | Structures of the Neisseria meningitides methionine-binding protein MetQ in substrate-free form and bound to l- and d-methionine isomers. Protein Sci., 28, 2019
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1G5P
| NITROGENASE IRON PROTEIN FROM AZOTOBACTER VINELANDII | Descriptor: | IRON/SULFUR CLUSTER, NITROGENASE IRON PROTEIN | Authors: | Strop, P, Takahara, P.M, Chiu, H.J, Angove, H.C, Burgess, B.K, Rees, D.C. | Deposit date: | 2000-11-01 | Release date: | 2001-01-31 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of the all-ferrous [4Fe-4S]0 form of the nitrogenase iron protein from Azotobacter vinelandii. Biochemistry, 40, 2001
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3PSA
| Classification of a Haemophilus influenzae ABC transporter HI1470/71 through its cognate molybdate periplasmic binding protein MolA (MolA bound to tungstate) | Descriptor: | TUNGSTATE(VI)ION, protein HI_1472 | Authors: | Tirado-Lee, L, Lee, A, Rees, D.C, Pinkett, H.W. | Deposit date: | 2010-12-01 | Release date: | 2011-11-30 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Classification of a Haemophilus influenzae ABC Transporter HI1470/71 through Its Cognate Molybdate Periplasmic Binding Protein, MolA. Structure, 19, 2011
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