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PDB: 135 results
2L6A
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BU of 2l6a by Molmil
Three-dimensional structure of the N-terminal effector PYRIN domain of NLRP12
Descriptor: NACHT, LRR and PYD domains-containing protein 12
Authors:Pinheiro, A.S, Peti, W.
Deposit date:2010-11-17
Release date:2011-11-02
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The NLRP12 pyrin domain: structure, dynamics, and functional insights.
J.Mol.Biol., 413, 2011
2LLZ
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BU of 2llz by Molmil
GhoS (YjdK) monomer
Descriptor: Uncharacterized protein yjdK
Authors:Lord, D, Peti, W, Page, R.
Deposit date:2011-11-18
Release date:2012-09-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A new type V toxin-antitoxin system where mRNA for toxin GhoT is cleaved by antitoxin GhoS.
Nat.Chem.Biol., 8, 2012
2M83
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BU of 2m83 by Molmil
Solution structure of the carbohydrate binding module of the muscle glycogen-targeting subunit of Protein Phosphatase-1
Descriptor: Protein phosphatase 1 regulatory subunit 3A
Authors:Koveal, D, Page, R, Peti, W.
Deposit date:2013-05-03
Release date:2014-05-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Molecular basis for Protein Phosphatase-1 regulation by the muscle glycogen-targeting subunit GM
To be Published
2M3V
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BU of 2m3v by Molmil
Solution structure of tyrosine phosphatase related to biofilm formation A (TpbA) from Pseudomonas aeruginosa
Descriptor: Putative uncharacterized protein
Authors:Koveal, D, Peti, W, Page, R.
Deposit date:2013-01-26
Release date:2013-04-03
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Ligand Binding Reduces Conformational Flexibility in the Active Site of Tyrosine Phosphatase Related to Biofilm Formation A (TpbA) from Pseudomonasaeruginosa.
J.Mol.Biol., 425, 2013
2NSW
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BU of 2nsw by Molmil
NMR Solution Structure of the Pheromone En-2
Descriptor: Mating pheromone En-2
Authors:Placzek, W.J, Etezady-Esfarjani, T, Herrmann, T, Peti, W, Wuthrich, K.
Deposit date:2006-11-06
Release date:2007-08-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR Solution Structures of the Pheromones En-1 and En-2 from the Antarctic Ciliated Protozoan Euplotes nobilii
To be Published
2NSV
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BU of 2nsv by Molmil
NMR Solution Structure of the Pheromone En-1
Descriptor: Mating pheromone En-1
Authors:Placzek, W.J, Etezady-Esfarjani, T, Herrmann, T, Peti, W, Wuthrich, K.
Deposit date:2006-11-06
Release date:2007-08-21
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:NMR Solution Structures of the Pheromones En-1 and En-2 from the Antarctic Ciliated Protozoan Euplotes Nobilii
To be Published
7MNA
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BU of 7mna by Molmil
PTP1B 1-284 F225Y-R199N in complex with TCS401
Descriptor: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MN7
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BU of 7mn7 by Molmil
PTP1B F225Y in complex with TCS401
Descriptor: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNE
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BU of 7mne by Molmil
PTP1B P206G mutation, open state
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MKZ
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BU of 7mkz by Molmil
PTP1B F225Y mutant, open state
Descriptor: CHLORIDE ION, GLYCEROL, Tyrosine-protein phosphatase non-receptor type 1
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-27
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNC
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BU of 7mnc by Molmil
PTP1B L204A
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Tyrosine-protein phosphatase non-receptor type 1
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNF
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BU of 7mnf by Molmil
PTP1B P206G in complex with TCS401
Descriptor: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MND
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BU of 7mnd by Molmil
PTP1B L204A in complex with TCS401
Descriptor: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MNB
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BU of 7mnb by Molmil
PTP1B F225Y-R199N-L195R in complex with TCS401
Descriptor: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, CHLORIDE ION, GLYCEROL, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MN9
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BU of 7mn9 by Molmil
PTP1B 1-284 F225Y-R199N
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-04-30
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.24 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MOV
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BU of 7mov by Molmil
PTP1B 1-301 F225Y-R199N mutations
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-05-03
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MOW
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BU of 7mow by Molmil
PTP1B F225I in complex with TCS401
Descriptor: 2-(OXALYL-AMINO)-4,5,6,7-TETRAHYDRO-THIENO[2,3-C]PYRIDINE-3-CARBOXYLIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-05-03
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
7MOU
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BU of 7mou by Molmil
PTP1B F225Y-R199N-L195R
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Torgeson, K.R, Page, R, Peti, W.
Deposit date:2021-05-03
Release date:2022-05-18
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Conserved conformational dynamics determine enzyme activity.
Sci Adv, 8, 2022
6OBP
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BU of 6obp by Molmil
Reconstituted PP1 holoenzyme
Descriptor: CHLORIDE ION, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
Deposit date:2019-03-21
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OBQ
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BU of 6obq by Molmil
PP1 H66K in complex with Microcystin LR
Descriptor: MANGANESE (II) ION, Microcystin LR, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
Authors:Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
Deposit date:2019-03-21
Release date:2019-09-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OBU
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BU of 6obu by Molmil
PP1 Y134K in complex with Microcystin LR
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
Deposit date:2019-03-21
Release date:2019-09-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OBN
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BU of 6obn by Molmil
The crystal structure of coexpressed SDS22:PP1 complex
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, FE (III) ION, ...
Authors:Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
Deposit date:2019-03-21
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OBR
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BU of 6obr by Molmil
PP1 Y134A in complex with Microcystin LR
Descriptor: CHLORIDE ION, MANGANESE (II) ION, Microcystin LR, ...
Authors:Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
Deposit date:2019-03-21
Release date:2019-09-18
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OBS
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BU of 6obs by Molmil
PP1 Y134K
Descriptor: GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R.
Deposit date:2019-03-21
Release date:2019-09-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.803 Å)
Cite:SDS22 selectively recognizes and traps metal-deficient inactive PP1.
Proc.Natl.Acad.Sci.USA, 116, 2019
3E7B
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BU of 3e7b by Molmil
Crystal Structure of Protein Phosphatase-1 Bound to the natural toxin inhibitor Tautomycin
Descriptor: (2Z)-2-[(1R)-3-{[(1R,2S,3R,6S,7S,10R)-10-{(2S,3S,6R,8S,9R)-3,9-dimethyl-8-[(3S)-3-methyl-4-oxopentyl]-1,7-dioxaspiro[5.5]undec-2-yl}-3,7-dihydroxy-2-methoxy-6-methyl-1-(1-methylethyl)-5-oxoundecyl]oxy}-1-hydroxy-3-oxopropyl]-3-methylbut-2-enedioic acid, AZIDE ION, CHLORIDE ION, ...
Authors:Kelker, M.S, Page, R, Peti, W.
Deposit date:2008-08-18
Release date:2008-11-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors
J.Mol.Biol., 385, 2009

219869

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