PDB Search results for query - Protein Data Bank Japan

PDB: 27 results

HUMAN SPLEEN TYROSINE KINASE KINASE DOMAIN IN COMPLEX WITH AZANAPHTHYRIDINE INHIBITOR
Descriptor:	7-[6-(dimethylamino)pyridin-3-yl]-~{N}-[[(3~{S})-piperidin-3-yl]methyl]pyrido[3,4-b]pyrazin-5-amine, GLYCEROL, Tyrosine-protein kinase SYK
Authors:	Somers, D.O, Neu, M.
Deposit date:	2016-07-29
Release date:	2016-09-14
Last modified:	2024-05-01
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Optimisation of a novel series of potent and orally bioavailable azanaphthyridine SYK inhibitors. Bioorg.Med.Chem.Lett., 26, 2016

5-aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors
Descriptor:	5-(4-METHOXYPHENYL)-N-(PYRIDIN-4-YLMETHYL)-1,3-OXAZOLE-4-CARBOXAMIDE, GLYCEROL, GLYCOGEN SYNTHASE KINASE-3 BETA, ...
Authors:	Gentile, G, Merlo, G, Pozzan, A, Bernasconi, G, Bax, B, Bamborough, P, Bridges, A, Carter, P, Neu, M, Yao, G, Brough, C, Cutler, G, Coffin, A, Belyanskaya, S.
Deposit date:	2012-01-19
Release date:	2012-02-29
Last modified:	2023-12-20
Method:	X-RAY DIFFRACTION (1.98 Å)
Cite:	5-Aryl-4-Carboxamide-1,3-Oxazoles: Potent and Selective Gsk-3 Inhibitors. Bioorg.Med.Chem.Lett., 22, 2012