PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Disease
Descriptor:	(2R)-2-methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-N-[2,2,2-tris(fluoranyl)ethyl]butanamide, Tyrosine-protein kinase JAK2
Authors:	Zuccola, H.J, Ledeboer, M.
Deposit date:	2015-03-17
Release date:	2015-08-12
Last modified:	2015-10-07
Method:	X-RAY DIFFRACTION (2.52 Å)
Cite:	Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J.Med.Chem., 58, 2015

Discovery of VX-509 (Decernotinib): A Potent and Selective Janus kinase (JAK) 3 Inhibitor for the Treatment of Autoimmune Disease
Descriptor:	N~3~-phenyl-1-[6-(phenylamino)pyrimidin-4-yl]-1H-1,2,4-triazole-3,5-diamine, Tyrosine-protein kinase JAK2
Authors:	Zuccola, H.J, Ledeboer, M.
Deposit date:	2015-03-17
Release date:	2015-08-12
Last modified:	2015-10-07
Method:	X-RAY DIFFRACTION (2.16 Å)
Cite:	Discovery of VX-509 (Decernotinib): A Potent and Selective Janus Kinase 3 Inhibitor for the Treatment of Autoimmune Diseases. J.Med.Chem., 58, 2015