2KLE
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![BU of 2kle by Molmil](/molmil-images/mine/2kle) | |
2KLD
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![BU of 2kld by Molmil](/molmil-images/mine/2kld) | |
1QR5
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![BU of 1qr5 by Molmil](/molmil-images/mine/1qr5) | SOLUTION STRUCTURE OF HISTIDINE CONTAINING PROTEIN (HPR) FROM STAPHYLOCOCCUS CARNOSUS | Descriptor: | PHOSPHOCARRIER PROTEIN HPR | Authors: | Kalbitzer, H.R, Gorler, A, Li, H, Dubovskii, P.V, Hengstenberg, W, Kowolik, C, Yamada, H, Akasaka, K. | Deposit date: | 1999-05-19 | Release date: | 2000-06-21 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | 15N and 1H NMR study of histidine containing protein (HPr) from Staphylococcus carnosus at high pressure. Protein Sci., 9, 2000
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7OGF
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![BU of 7ogf by Molmil](/molmil-images/mine/7ogf) | GTPase HRAS mutant D33K under 900 MPa pressure | Descriptor: | GTPase HRas, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. | Deposit date: | 2021-05-06 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
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7OGA
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![BU of 7oga by Molmil](/molmil-images/mine/7oga) | GTPase HRAS under 200 MPa pressure | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Colloc'h, N.C, Kalbitzer, H.R, Girard, E, Prange, T. | Deposit date: | 2021-05-06 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
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7OGC
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![BU of 7ogc by Molmil](/molmil-images/mine/7ogc) | GTPase HRAS under 650 MPa pressure | Descriptor: | GTPase HRas, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. | Deposit date: | 2021-05-06 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
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7OGB
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![BU of 7ogb by Molmil](/molmil-images/mine/7ogb) | GTPase HRAS under 500 MPa pressure | Descriptor: | GTPase HRas, MAGNESIUM ION, PENTAETHYLENE GLYCOL, ... | Authors: | Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. | Deposit date: | 2021-05-06 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
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7OGE
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![BU of 7oge by Molmil](/molmil-images/mine/7oge) | GTPase HRAS mutant D33K under 200 MPa pressure | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. | Deposit date: | 2021-05-06 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
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7OGD
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![BU of 7ogd by Molmil](/molmil-images/mine/7ogd) | GTPase HRAS mutant D33K under ambient pressure | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Colloc'h, N.C, Girard, E, Prange, T, Kalbitzer, H.R. | Deposit date: | 2021-05-06 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
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7OG9
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![BU of 7og9 by Molmil](/molmil-images/mine/7og9) | GTPase HRAS under ambient pressure | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Colloc'h, N, Girard, E, Prange, T, Kalbitzer, H.R. | Deposit date: | 2021-05-06 | Release date: | 2022-02-09 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Equilibria between conformational states of the Ras oncogene protein revealed by high pressure crystallography. Chem Sci, 13, 2022
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2RGF
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![BU of 2rgf by Molmil](/molmil-images/mine/2rgf) | RBD OF RAL GUANOSINE-NUCLEOTIDE EXCHANGE FACTOR (PROTEIN), NMR, 10 STRUCTURES | Descriptor: | RALGEF-RBD | Authors: | Geyer, M, Herrmann, C, Wittinghofer, A, Kalbitzer, H.R. | Deposit date: | 1997-02-13 | Release date: | 1998-03-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structure of the Ras-binding domain of RalGEF and implications for Ras binding and signalling. Nat.Struct.Biol., 4, 1997
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2B3A
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![BU of 2b3a by Molmil](/molmil-images/mine/2b3a) | Solution structure of the Ras-binding domain of the Ral Guanosine Dissociation Stimulator | Descriptor: | Ral guanine nucleotide dissociation stimulator | Authors: | Gronwald, W, Maurer, T, Fuechsl, R, Wohlgemuth, S, Herrmann, C, Kalbitzer, H.R. | Deposit date: | 2005-09-20 | Release date: | 2006-09-26 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | New insights into binding of the possible cancer target RalGDS To be Published
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1TXE
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![BU of 1txe by Molmil](/molmil-images/mine/1txe) | Solution structure of the active-centre mutant Ile14Ala of the histidine-containing phosphocarrier protein (HPr) from Staphylococcus carnosus | Descriptor: | Phosphocarrier protein HPr | Authors: | Moeglich, A, Koch, B, Hengstenberg, W, Brunner, E, Kalbitzer, H.R, Structural Proteomics in Europe (SPINE) | Deposit date: | 2004-07-04 | Release date: | 2005-03-08 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the active-centre mutant I14A of the histidine-containing phosphocarrier protein from Staphylococcus carnosus Eur.J.Biochem., 271, 2004
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8OSN
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![BU of 8osn by Molmil](/molmil-images/mine/8osn) | GTPASE HRAS IN COMPLEX WITH ZN-CYCLEN AT AMBIENT PRESSURE | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Colloc'h, N, Prange, T, Girard, E, Kalbitzer, H.R. | Deposit date: | 2023-04-19 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High pressure promotes binding of the allosteric inhibitor Zn2+-cyclen in crystals of activated H-Ras. Chemistry, 2024
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8OSO
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![BU of 8oso by Molmil](/molmil-images/mine/8oso) | GTPase HRAS in complex with Zn-cyclen under 500 MPa pressure | Descriptor: | 1,4,7,10-tetraazacyclododecane, GTPase HRas, MAGNESIUM ION, ... | Authors: | Colloc'h, N, Prange, T, Girard, E, Kalbitzer, H.R. | Deposit date: | 2023-04-19 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | High pressure promotes binding of the allosteric inhibitor Zn2+-cyclen in crystals of activated H-Ras. Chemistry, 2024
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8OSM
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![BU of 8osm by Molmil](/molmil-images/mine/8osm) | GTPASE HRAS IN COMPLEX WITH ZN-CYCLEN AT 200 MPA PRESSURE | Descriptor: | GTPase HRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | Authors: | Colloc'h, N, Girard, E, Prange, T, Kalbitzer, H.R. | Deposit date: | 2023-04-19 | Release date: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | High pressure promotes binding of the allosteric inhibitor Zn2+-cyclen in crystals of activated H-Ras. Chemistry, 2024
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1G6P
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![BU of 1g6p by Molmil](/molmil-images/mine/1g6p) | SOLUTION NMR STRUCTURE OF THE COLD SHOCK PROTEIN FROM THE HYPERTHERMOPHILIC BACTERIUM THERMOTOGA MARITIMA | Descriptor: | COLD SHOCK PROTEIN TMCSP | Authors: | Kremer, W, Schuler, B, Harrieder, S, Geyer, M, Gronwald, W, Welker, C, Jaenicke, R, Kalbitzer, H.R. | Deposit date: | 2000-11-07 | Release date: | 2001-11-07 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of the cold-shock protein from the hyperthermophilic bacterium Thermotoga maritima. Eur.J.Biochem., 268, 2001
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1I35
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![BU of 1i35 by Molmil](/molmil-images/mine/1i35) | SOLUTION STRUCTURE OF THE RAS-BINDING DOMAIN OF THE PROTEIN KINASE BYR2 FROM SCHIZOSACCHAROMYCES POMBE | Descriptor: | PROTEIN KINASE BYR2 | Authors: | Gronwald, W, Huber, F, Grunewald, P, Sporner, M, Wohlgemuth, S, Herrmann, C, Kalbitzer, H.R. | Deposit date: | 2001-02-13 | Release date: | 2001-12-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the Ras binding domain of the protein kinase Byr2 from Schizosaccharomyces pombe. Structure, 9, 2001
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2QMV
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![BU of 2qmv by Molmil](/molmil-images/mine/2qmv) | |
1XKE
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![BU of 1xke by Molmil](/molmil-images/mine/1xke) | Solution structure of the second Ran-binding domain from human RanBP2 | Descriptor: | Ran-binding protein 2 | Authors: | Geyer, J.P, Doeker, R, Kremer, W, Zhao, X, Kuhlmann, J, Kalbitzer, H.R. | Deposit date: | 2004-09-28 | Release date: | 2005-04-19 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of the Ran-binding domain 2 of RanBP2 and its interaction with the C terminus of Ran. J.Mol.Biol., 348, 2005
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3L8Z
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![BU of 3l8z by Molmil](/molmil-images/mine/3l8z) | H-Ras wildtype new crystal form | Descriptor: | CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... | Authors: | Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R. | Deposit date: | 2010-01-04 | Release date: | 2011-01-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.44 Å) | Cite: | Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes Angew.Chem.Int.Ed.Engl., 49, 2010
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4BGC
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![BU of 4bgc by Molmil](/molmil-images/mine/4bgc) | |
3L8Y
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![BU of 3l8y by Molmil](/molmil-images/mine/3l8y) | Complex of Ras with cyclen | Descriptor: | 1,4,7,10-tetraazacyclododecane, CALCIUM ION, GTPase HRas, ... | Authors: | Rosnizeck, I.C, Graf, T, Spoerner, M, Traenkle, J, Filchtinski, D, Herrmann, C, Gremer, L, Vetter, I.R, Wittinghofer, A, Koenig, B, Kalbitzer, H.R. | Deposit date: | 2010-01-04 | Release date: | 2011-01-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.02 Å) | Cite: | Stabilizing a weak binding state for effectors in the human ras protein by cyclen complexes Angew.Chem.Int.Ed.Engl., 49, 2010
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1ZTO
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![BU of 1zto by Molmil](/molmil-images/mine/1zto) | INACTIVATION GATE OF POTASSIUM CHANNEL RCK4, NMR, 8 STRUCTURES | Descriptor: | POTASSIUM CHANNEL PROTEIN RCK4 | Authors: | Antz, C, Geyer, M, Fakler, B, Schott, M, Frank, R, Guy, H.R, Ruppersberg, J.P, Kalbitzer, H.R. | Deposit date: | 1996-11-15 | Release date: | 1997-06-05 | Last modified: | 2022-03-02 | Method: | SOLUTION NMR | Cite: | NMR structure of inactivation gates from mammalian voltage-dependent potassium channels. Nature, 385, 1997
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1ZTN
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![BU of 1ztn by Molmil](/molmil-images/mine/1ztn) | INACTIVATION GATE OF POTASSIUM CHANNEL RAW3, NMR, 8 STRUCTURES | Descriptor: | Potassium voltage-gated channel subfamily C member 4 | Authors: | Antz, C, Geyer, M, Fakler, B, Schott, M, Frank, R, Guy, H.R, Ruppersberg, J.P, Kalbitzer, H.R. | Deposit date: | 1996-11-15 | Release date: | 1997-06-05 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structure of inactivation gates from mammalian voltage-dependent potassium channels. Nature, 385, 1997
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