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PDB: 5173 results

4ESJ
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RESTRICTION ENDONUCLEASE DpnI IN COMPLEX WITH TARGET DNA
Descriptor: AZIDE ION, DNA (5'-D(*CP*TP*GP*GP*(6MA)P*TP*CP*CP*AP*G)-3'), GLYCEROL, ...
Authors:Siwek, W, Czapinska, H, Bochtler, M, Bujnicki, J.M, Skowronek, K.
Deposit date:2012-04-23
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI.
Nucleic Acids Res., 40, 2012
1VTP
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VACUOLAR TARGETING PEPTIDE FROM NA-PROPI
Descriptor: VACUOLAR TARGETING PEPTIDE
Authors:Nielsen, K.J, Hill, J.M, Anderson, M.A, Craik, D.J.
Deposit date:1995-11-14
Release date:1996-03-08
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Synthesis and structure determination by NMR of a putative vacuolar targeting peptide and model of a proteinase inhibitor from Nicotiana alata.
Biochemistry, 35, 1996
1W5Z
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AGAO covalent complex with Benzylhydrazine
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Duff, A.P, Trambaiolo, D.M, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M.
Deposit date:2004-08-11
Release date:2005-12-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Complexes of the Copper-Containing Amine Oxidase from Arthrobacter Globiformis with the Inhibitors Benzylhydrazine and Tranylcypromine.
Acta Crystallogr.,Sect.F, 64, 2008
1W6C
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AGAO holoenzyme in a small cell, at 2.2 angstroms
Descriptor: COPPER (II) ION, PHENYLETHYLAMINE OXIDASE, SODIUM ION
Authors:Duff, A.P, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M.
Deposit date:2004-08-17
Release date:2005-12-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Copper Containing Amine Oxidase from Arthrobacter Globiformis: Refinement at 1.55 And 2.20 A Resolution in Two Crystal Forms.
Acta Crystallogr.,Sect.F, 62, 2006
4F08
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Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
Descriptor: 1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
Authors:Murray, J.M.
Deposit date:2012-05-03
Release date:2012-07-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2.
J.Med.Chem., 55, 2012
1W6G
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AGAO holoenzyme at 1.55 angstroms
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Langley, D.B, Duff, A.P, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M.
Deposit date:2004-08-18
Release date:2005-12-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The Copper Containing Amine Oxidase from Arthrobacter Globiformis: Refinement at 1.55 And 2.20 A Resolution in Two Crystal Forms.
Acta Crystallogr.,Sect.F, 62, 2006
1W2M
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Ca-substituted form of E. coli aminopeptidase P
Descriptor: CALCIUM ION, CHLORIDE ION, ISOPROPYL ALCOHOL, ...
Authors:Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M.
Deposit date:2004-07-07
Release date:2005-09-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
Biochemistry, 44, 2005
1W4N
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AGAO covalent complex with Tranylcypromine
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Duff, A.P, Trambaiolo, D.M, Langley, D.B, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M.
Deposit date:2004-07-27
Release date:2005-12-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Complexes of the Copper-Containing Amine Oxidase from Arthrobacter Globiformis with the Inhibitors Benzylhydrazine and Tranylcypromine.
Acta Crystallogr.,Sect.F, 64, 2008
1W52
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Crystal structure of a proteolyzed form of pancreatic lipase related protein 2 from horse
Descriptor: CALCIUM ION, DECYLAMINE-N,N-DIMETHYL-N-OXIDE, PANCREATIC LIPASE RELATED PROTEIN 2
Authors:Mancheno, J.M, Jayne, S, Kerfelec, B, Chapus, C, Crenon, I, Hermoso, J.A.
Deposit date:2004-08-04
Release date:2006-07-12
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Crystalization of a Proteolyzed Form of the Horse Pancreatic Lipase-Related Protein 2: Structural Basis for the Specific Detergent Requirement.
Acta Crystallogr.,Sect.D, 60, 2004
4F0R
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Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) bound Zn and 5'-Methylthioadenosine (unproductive complex)
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, 5-methylthioadenosine/S-adenosylhomocysteine deaminase, GLYCEROL, ...
Authors:Kim, J, Vetting, M.W, Sauder, J.M, Burley, S.K, Raushel, F.M, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-05-04
Release date:2012-06-06
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) bound Zn and 5'-Methylthioadenosine (unproductive complex)
To be Published
1W47
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P4 protein from Bacteriophage PHI12 in complex with ADP and MN
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, NTPASE P4
Authors:Mancini, E.J, Kainov, D.E, Grimes, J.M, Tuma, R, Bamford, D.H, Stuart, D.I.
Deposit date:2004-07-22
Release date:2004-11-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Atomic Snapshots of an RNA Packaging Motor Reveal Conformational Changes Linking ATP Hydrolysis to RNA Translocation
Cell(Cambridge,Mass.), 118, 2004
1W46
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P4 protein from Bacteriophage PHI12 in complex with ADP and MG
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NTPASE P4
Authors:Mancini, E.J, Kainov, D.E, Grimes, J.M, Tuma, R, Bamford, D.H, Stuart, D.I.
Deposit date:2004-07-22
Release date:2004-11-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Atomic Snapshots of an RNA Packaging Motor Reveal Conformational Changes Linking ATP Hydrolysis to RNA Translocation
Cell(Cambridge,Mass.), 118, 2004
1VZ7
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Ornithine Acetyltransferase (ORF6 Gene Product - Clavulanic Acid Biosynthesis) from Streptomyces clavuligerus
Descriptor: ORNITHINE ACETYL-TRANSFERASE, SULFATE ION
Authors:Elkins, J.M, Kershaw, N.J, Schofield, C.J.
Deposit date:2004-05-14
Release date:2004-09-16
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-Ray Crystal Structure of Ornithine Acetyltransferase from the Clavulanic Acid Biosynthesis Gene Cluster.
Biochem.J., 385, 2005
3L25
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Crystal structure of Zaire Ebola VP35 interferon inhibitory domain bound to 8 bp dsRNA
Descriptor: CHLORIDE ION, FORMIC ACID, GLYCEROL, ...
Authors:Leung, D.W, Prins, K.C, Borek, D.M, Farahbakhsh, M, Tufariello, J.M, Ramanan, P, Nix, J.C, Helgeson, L.A, Otwinowski, Z, Honzatko, R.B, Basler, C.F, Amarasinghe, G.K.
Deposit date:2009-12-14
Release date:2010-01-26
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for dsRNA recognition and interferon antagonism by Ebola VP35.
Nat.Struct.Mol.Biol., 17, 2010
1W4B
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P4 protein from PHI12 in complex with product (AMPcPP Mg 22C)
Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NTPASE P4
Authors:Mancini, E.J, Kainov, D.E, Grimes, J.M, Tuma, R, Bamford, D.H, Stuart, D.I.
Deposit date:2004-07-22
Release date:2004-11-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Atomic Snapshots of an RNA Packaging Motor Reveal Conformational Changes Linking ATP Hydrolysis to RNA Translocation
Cell(Cambridge,Mass.), 118, 2004
1W48
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P4 protein from Bacteriophage PHI12 in complex with AMPcPP
Descriptor: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, NTPASE P4
Authors:Mancini, E.J, Kainov, D.E, Grimes, J.M, Tuma, R, Bamford, D.H, Stuart, D.I.
Deposit date:2004-07-22
Release date:2004-10-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Atomic Snapshots of an RNA Packaging Motor Reveal Conformational Changes Linking ATP Hydrolysis to RNA Translocation
Cell(Cambridge,Mass.), 118, 2004
1W8Q
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BU of 1w8q by Molmil
Crystal Structure of the DD-Transpeptidase-carboxypeptidase from Actinomadura R39
Descriptor: COBALT (II) ION, D-ALANYL-D-ALANINE CARBOXYPEPTIDASE, SULFATE ION
Authors:Sauvage, E, Herman, R, Petrella, S, Duez, C, Frere, J.M, Charlier, P.
Deposit date:2004-09-24
Release date:2005-06-28
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystal Structure of the Actinomadura R39 Dd-Peptidase Reveals New Domains in Penicillin-Binding Proteins.
J.Biol.Chem., 280, 2005
1W44
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P4 protein from Bacteriophage PHI12 in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, NTPASE P4
Authors:Mancini, E.J, Kainov, D.E, Grimes, J.M, Tuma, R, Bamford, D.H, Stuart, D.I.
Deposit date:2004-07-22
Release date:2004-10-29
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Atomic Snapshots of an RNA Packaging Motor Reveal Conformational Changes Linking ATP Hydrolysis to RNA Translocation
Cell(Cambridge,Mass.), 118, 2004
4EZ1
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Crystal structure of acetylcholine binding protein (AChBP) from Aplysia Californica in complex with alpha-conotoxin BuIA
Descriptor: Alpha-conotoxin BuIA, MANGANESE (II) ION, Soluble acetylcholine receptor
Authors:Talley, T.T, Reger, A.S, Kim, C, Sankaran, B, Ho, K, Taylor, P, McIntosh, J.M.
Deposit date:2012-05-02
Release date:2013-05-08
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Pairwise interaction of alpha-conotoxin BuIA Pro6 with the beta subunit of nicotinic acetylcholine receptor
To be Published
4F09
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Discovery and Optimization of C-2 Methyl Imidazo-pyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2
Descriptor: 2-methyl-1-(piperidin-4-yl)-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridine, Tyrosine-protein kinase JAK2
Authors:Murray, J.M.
Deposit date:2012-05-03
Release date:2012-07-04
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Discovery and Optimization of C-2 Methyl Imidazopyrrolopyridines as Potent and Orally Bioavailable JAK1 Inhibitors with Selectivity over JAK2.
J.Med.Chem., 55, 2012
4F0S
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Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) with bound inosine.
Descriptor: 5-methylthioadenosine/S-adenosylhomocysteine deaminase, CHLORIDE ION, INOSINE, ...
Authors:Kim, J, Vetting, M.W, Sauder, J.M, Burley, S.K, Raushel, F.M, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC)
Deposit date:2012-05-04
Release date:2012-06-06
Last modified:2021-02-10
Method:X-RAY DIFFRACTION (1.851 Å)
Cite:Crystal structure of an adenosine deaminase homolog from Chromobacterium violaceum (target NYSGRC-019589) with bound inosine.
To be Published
4F37
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Structure of the tethered N-terminus of Alzheimer's disease A peptide
Descriptor: Colicin-E7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment, Im7 immunity protein
Authors:Nisbet, R.M, Nuttall, S.D, Caine, J.M, Rober, R, Hittaki, M, Pearce, L.A, Davydova, N, Masters, C.L, Varghese, J.N, Streltsov, V.A.
Deposit date:2012-05-09
Release date:2013-05-15
Last modified:2014-09-03
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013
1WO3
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Solution structure of Minimal Mutant 1 (MM1): Multiple alanine mutant of non-native CHANCE domain
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P.
Deposit date:2004-08-12
Release date:2005-03-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
1WO6
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Solution structure of Designed Functional Finger 5 (DFF5): Designed mutant based on non-native CHANCE domain
Descriptor: CREB Binding Protein, ZINC ION
Authors:Sharpe, B.K, Liew, C.K, Wilce, J.A, Crossley, M, Matthews, J.M, Mackay, J.P.
Deposit date:2004-08-12
Release date:2005-03-08
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting
Structure, 13, 2005
1WPD
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Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
Descriptor: Potassium channel toxin alpha-KTx 6.2,Potassium channel toxin alpha-KTx 6.3
Authors:Regaya, I, Beeton, C, Ferrat, G, Andreotti, N, Chandy, G.K, Darbon, H, De Waard, M, Sabatier, J.M.
Deposit date:2004-09-01
Release date:2004-10-19
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
J.Biol.Chem., 279, 2004

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