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PDB: 13 results

8TH1
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BU of 8th1 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein D3L mutant
Descriptor: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
Authors:Hughes, M.P, Taylor, J.P, Yang, Z.
Deposit date:2023-07-13
Release date:2023-12-27
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
7N8R
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BU of 7n8r by Molmil
FGTGFG segment from the Nucleoporin p54, residues 63-68
Descriptor: FGTGFG segment from the Nucleoporin p54, residues 63-68, trifluoroacetic acid
Authors:Hughes, M.P, Sawaya, M.R, Eisenberg, D.S.
Deposit date:2021-06-15
Release date:2022-02-16
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Extended beta-Strands Contribute to Reversible Amyloid Formation.
Acs Nano, 16, 2022
8TH7
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Crystal Structure of the G3BP1 NTF2-like domain bound to the Caprin1 peptide
Descriptor: Caprin-1, Ras GTPase-activating protein-binding protein 1
Authors:Hughes, M.P, Taylor, J.P, Yang, Z.
Deposit date:2023-07-14
Release date:2024-03-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH6
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Crystal Structure of the G3BP1 NTF2-like domain bound to USP10 peptide
Descriptor: 1,2-ETHANEDIOL, Ras GTPase-activating protein-binding protein 1, Ubiquitin carboxyl-terminal hydrolase 10
Authors:Hughes, M.P, Taylor, J.P, Yang, Z.
Deposit date:2023-07-14
Release date:2024-03-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.34 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
8TH5
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BU of 8th5 by Molmil
Crystal Structure of the G3BP1 NTF2-like domain bound to the IDR1 of SARS-CoV-2 nucleocapsid protein P13L mutant
Descriptor: Nucleoprotein, Ras GTPase-activating protein-binding protein 1
Authors:Hughes, M.P, Taylor, J.P, Yang, Z.
Deposit date:2023-07-13
Release date:2024-03-20
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.62 Å)
Cite:Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity.
Cell Rep, 43, 2024
6BWZ
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BU of 6bwz by Molmil
SYSGYS from low-complexity domain of FUS, residues 37-42
Descriptor: SYSGYS peptide from low-complexity domain of FUS
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Tamir, G, Eisenberg, D.S.
Deposit date:2017-12-15
Release date:2018-04-04
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
6BZP
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BU of 6bzp by Molmil
STGGYG from low-complexity domain of FUS, residues 77-82
Descriptor: 2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL, RNA-binding protein FUS
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S.
Deposit date:2017-12-25
Release date:2018-04-04
Last modified:2024-03-13
Method:ELECTRON CRYSTALLOGRAPHY (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
6BZM
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BU of 6bzm by Molmil
GFGNFGTS from low-complexity/FG repeat domain of Nup98, residues 116-123
Descriptor: Nuclear pore complex protein Nup98-Nup96
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Chong, L, Gonen, T, Eisenberg, D.S.
Deposit date:2017-12-24
Release date:2018-04-04
Last modified:2024-03-13
Method:ELECTRON CRYSTALLOGRAPHY (0.9 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
6BXV
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BU of 6bxv by Molmil
SYSSYGQS from low-complexity domain of FUS, residues 54-61
Descriptor: FUS
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S.
Deposit date:2017-12-19
Release date:2018-04-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
6BXX
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BU of 6bxx by Molmil
GYNGFG from low-complexity domain of hnRNPA1, residues 243-248
Descriptor: hnRNPA1
Authors:Hughes, M.P, Rodriguez, J.A, Sawaya, M.R, Cascio, D, Gonen, T, Eisenberg, D.S.
Deposit date:2017-12-19
Release date:2018-04-04
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Atomic structures of low-complexity protein segments reveal kinked beta sheets that assemble networks.
Science, 359, 2018
8V1L
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BU of 8v1l by Molmil
Crystal structure of the NTF2L domain of human G3BP1 in complex with small molecule
Descriptor: N-[(2S)-2-fluoro-4,4-dimethylpentanoyl]-3-hydroxy-L-valyl-(betaS)-beta-methyl-L-phenylalanyl-D-alanyl-N-benzyl-N,O-dimethyl-L-homoserinamide, Ras GTPase-activating protein-binding protein 1
Authors:Hughes, M.P, Taylor, J.P.
Deposit date:2023-11-20
Release date:2024-02-14
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:Identification of small molecule inhibitors of G3BP-driven stress granule formation.
J.Cell Biol., 223, 2024
6WPQ
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BU of 6wpq by Molmil
GNYNVF from hnRNPA2-low complexity domain segment, residues 286-291, D290V variant
Descriptor: Heterogeneous nuclear ribonucleoprotein A2
Authors:Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S.
Deposit date:2020-04-27
Release date:2020-08-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid.
Nat Commun, 11, 2020
6WQK
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BU of 6wqk by Molmil
hnRNPA2 Low complexity domain (LCD) determined by cryoEM
Descriptor: MCherry fluorescent protein,Heterogeneous nuclear ribonucleoproteins A2/B1 chimera
Authors:Lu, J, Cao, Q, Hughes, M.P, Sawaya, M.R, Boyer, D.R, Cascio, D, Eisenberg, D.S.
Deposit date:2020-04-29
Release date:2020-08-26
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:CryoEM structure of the low-complexity domain of hnRNPA2 and its conversion to pathogenic amyloid.
Nat Commun, 11, 2020

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PDB entries from 2024-10-30

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