8P8H
| Crystal structure of HHD2 domain of hRTEL1 | Descriptor: | Regulator of telomere elongation helicase 1 | Authors: | Hegde, R.P, Kanade, M, Cortone, G, Graewert, M, Longo, A, Gonzalez, A, Chaves-Arquero, B, Blanco, F.J, Napolitano, L.M.R, Onesti, S. | Deposit date: | 2023-06-01 | Release date: | 2024-06-12 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of HHD2 domain of hRTEL1 To Be Published
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3BY1
| Unliganded Norvalk Virus P domain | Descriptor: | 58 kd capsid protein | Authors: | Hegde, R, Bu, W. | Deposit date: | 2008-01-15 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | Structural basis for the receptor binding specificity of Norwalk virus. J.Virol., 82, 2008
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4HN8
| Crystal structure of a putative D-glucarate dehydratase from Pseudomonas mendocina ymp | Descriptor: | D-glucarate dehydratase, GLYCEROL | Authors: | Hegde, R.P, Toro, R, Burley, S.K, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-10-19 | Release date: | 2012-11-07 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a putative D-glucarate dehydratase from Pseudomonas mendocina ymp To be published
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6Y4L
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4HYR
| Structure of putative Glucarate dehydratase from Acidaminococcus sp. D21 with unusual static disorder | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Hegde, R.P, Toro, R, Burley, S.K, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2012-11-14 | Release date: | 2013-02-13 | Last modified: | 2021-02-10 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | Structure of putative Glucarate dehydratase from Acidaminococcus sp. D21 with unusual static disorder To be published
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6Z3W
| Human ER membrane protein complex | Descriptor: | ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1,ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | Authors: | Hegde, R.S, O'Donnell, J.P. | Deposit date: | 2020-05-22 | Release date: | 2020-07-15 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.4 Å) | Cite: | The architecture of EMC reveals a path for membrane protein insertion. Elife, 9, 2020
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4JHM
| Crystal structure of a putative mandelate racemase/muconate lactonizing enzyme from Pseudovibrio sp. | Descriptor: | Mandelate racemase / muconate lactonizing enzyme, C-terminal domain protein | Authors: | Hegde, R.P, Toro, R, Burley, S.K, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-03-05 | Release date: | 2013-05-01 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of a putative mandelate racemase/muconate lactonizing enzyme from Pseudovibrio sp. To be published
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1BY9
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3D26
| Norwalk P domain A-trisaccharide complex | Descriptor: | 58 kd capsid protein, alpha-L-fucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-galactopyranose-(1-3)]beta-D-galactopyranose | Authors: | Hegde, R, Bu, W. | Deposit date: | 2008-05-07 | Release date: | 2008-06-10 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for the receptor binding specificity of Norwalk virus. J.Virol., 82, 2008
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2BOP
| CRYSTAL STRUCTURE AT 1.7 ANGSTROMS OF THE BOVINE PAPILLOMAVIRUS-1 E2 DNA-BINDING DOMAIN BOUND TO ITS DNA TARGET | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*CP*CP*GP*AP*CP*GP*TP*CP*GP*GP*TP*CP*G )-3'), PROTEIN (E2), YTTERBIUM (III) ION | Authors: | Hegde, R.S, Grossman, S.R, Laimins, L.A, Sigler, P.B. | Deposit date: | 1994-01-13 | Release date: | 1994-01-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structure at 1.7 A of the bovine papillomavirus-1 E2 DNA-binding domain bound to its DNA target. Nature, 359, 1992
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2F61
| Crystal structure of partially deglycosylated acid beta-glucosidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Acid beta-glucosidase, ... | Authors: | Hegde, R.S, Grabowski, G. | Deposit date: | 2005-11-28 | Release date: | 2005-12-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Analyses of Variant Acid beta-Glucosidases: EFFECTS OF GAUCHER DISEASE MUTATIONS. J.Biol.Chem., 281, 2006
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3BY2
| Norwalk P polypeptide (228-523) | Descriptor: | 58 kd capsid protein | Authors: | Hegde, R, Bu, W. | Deposit date: | 2008-01-15 | Release date: | 2008-04-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for the receptor binding specificity of Norwalk virus. J.Virol., 82, 2008
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1JJH
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1F9F
| CRYSTAL STRUCTURE OF THE HPV-18 E2 DNA-BINDING DOMAIN | Descriptor: | Regulatory protein E2, SULFATE ION | Authors: | Kim, S.S, Tam, J, Wang, A.F, Hegde, R. | Deposit date: | 2000-07-10 | Release date: | 2000-11-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis of DNA target discrimination by papillomavirus E2 proteins. J.Biol.Chem., 275, 2000
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4XWO
| Structure of Get3 bound to the transmembrane domain of Sec22 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ... | Authors: | Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J. | Deposit date: | 2015-01-29 | Release date: | 2015-03-25 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science, 347, 2015
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3BQJ
| VA387 polypeptide | Descriptor: | va387 polypeptide | Authors: | Bu, W, Mamedova, A, Tan, M, Jiang, J, Hegde, R. | Deposit date: | 2007-12-20 | Release date: | 2008-04-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for the receptor binding specificity of Norwalk virus. J.Virol., 82, 2008
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4XTR
| Structure of Get3 bound to the transmembrane domain of Pep12 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ... | Authors: | Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J. | Deposit date: | 2015-01-23 | Release date: | 2015-03-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science, 347, 2015
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4XVU
| Structure of Get3 bound to the transmembrane domain of Nyv1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Antibody heavy chain, ... | Authors: | Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J. | Deposit date: | 2015-01-28 | Release date: | 2015-03-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo. Science, 347, 2015
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8BPO
| Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 (TTC5) and S-phase Cyclin A Associated Protein residing in the ER (SCAPER) | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Hopfler, M, Absmeier, E, Passmore, L.A, Hegde, R.S. | Deposit date: | 2022-11-17 | Release date: | 2023-07-05 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation. Mol.Cell, 83, 2023
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7TM3
| Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-01-19 | Release date: | 2022-10-19 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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7TUT
| Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | Descriptor: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | Deposit date: | 2022-02-03 | Release date: | 2022-10-19 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.88 Å) | Cite: | Mechanism of an intramembrane chaperone for multipass membrane proteins. Nature, 611, 2022
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5LZU
| Structure of the mammalian ribosomal termination complex with accommodated eRF1 | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Shao, S, Murray, J, Brown, A, Taunton, J, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2016-10-02 | Release date: | 2016-11-30 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes. Cell, 167, 2016
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4MB6
| Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis. | Descriptor: | Adenine phosphoribosyltransferase, SODIUM ION | Authors: | Pavithra, G.C, Kim, J, Hegde, R.P, Almo, S.C, Ramagopal, U.A, New York Structural Genomics Research Consortium (NYSGRC) | Deposit date: | 2013-08-19 | Release date: | 2013-09-04 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystal structure of adenine phosphoribosyltransferase from Yersinia pseudotuberculosis To be published
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7QWS
| Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | Deposit date: | 2022-01-25 | Release date: | 2022-03-09 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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7QWR
| Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC | Descriptor: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | Authors: | Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. | Deposit date: | 2022-01-25 | Release date: | 2022-03-09 | Last modified: | 2022-03-23 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
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