3DMT
| Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in complex with the irreversible iodoacetate inhibitor | Descriptor: | GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, glycosomal, ... | Authors: | Guido, R.V.C, Balliano, T.L, Andricopulo, A.D, Oliva, G. | Deposit date: | 2008-07-01 | Release date: | 2008-10-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Kinetic and Crystallographic Studies on Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in Complex with Iodoacetate. Letters in drug design & discovery, 6, 2009
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6Q62
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6DAY
| Xanthomonas albilineans Dihydropteroate synthase with 4-aminobenzoic acid at 1.65 A | Descriptor: | 4-AMINOBENZOIC ACID, Dihydropteroate synthase, GLYCEROL, ... | Authors: | Oliveira, A.A, Guido, R.V.C, Lima, G.M.A, Bueno, R.V, Maluf, F.V. | Deposit date: | 2018-05-02 | Release date: | 2018-06-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Xanthomonas albilineans Dihydropteroate synthase with 4-aminobenzoic acid To Be Published
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5NHS
| The crystal structure of Xanthomonas albilineans N5, N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) | Descriptor: | 1,2-ETHANEDIOL, Bifunctional protein FolD | Authors: | Bueno, R.V, Guido, R.V.C, Maluf, F.V, Lima, G.M.A, Oliveira, A.A. | Deposit date: | 2017-03-22 | Release date: | 2018-05-16 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.11 Å) | Cite: | The crystal structure of Xanthomonas albilineans N5, N10-methylenetetrahydrofolate dehydrogenase-cyclohydrolase (FolD) To Be Published
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3IDS
| Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in complex with the irreversible iodoacetamide inhibitor | Descriptor: | ACETAMIDE, GLYCEROL, Glyceraldehyde-3-phosphate dehydrogenase, ... | Authors: | Balliano, T.L, Guido, R.V.C, Andricopulo, A.D, Oliva, G. | Deposit date: | 2009-07-21 | Release date: | 2009-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi in complex with the irreversible iodoacetamide inhibitor To be Published
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6OFW
| Dihydropteroate synthase from Xanthomonas albilineans in complex with 7,8-dihydropteroate | Descriptor: | 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoic acid, Dihydropteroate synthase, SULFATE ION | Authors: | Oliveira, A.A, Guido, R.V.C, Maluf, F.V, Bueno, R.V, Lima, G.M.A. | Deposit date: | 2019-04-01 | Release date: | 2020-04-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Dihydropteroate synthase from Xanthomonas albilineans in complex with 7,8-dihydropteroate To Be Published
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6MFB
| Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Serine--pyruvate aminotransferase | Authors: | Maciel, L.G, Oliveira, A.A, Romao, T.P, Silva Filha, M.H.N.L, dos Anjos, J.V, Soares, T.A, Guido, R.V.C. | Deposit date: | 2018-09-10 | Release date: | 2019-09-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of 3-hydroxykynurenine transaminase from Aedes aegypti To Be Published
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5U04
| Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase | Descriptor: | PHOSPHATE ION, ZINC ION, Zika Virus NS5 RdRp | Authors: | Godoy, A.S, Lima, G.M.A, Oliveira, K.I.Z, Torres, N.U, Maluf, F.V, Guido, R.V.C, Oliva, G. | Deposit date: | 2016-11-22 | Release date: | 2017-02-22 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase. Nat Commun, 8, 2017
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7MLK
| Crystal structure of human PI3Ka (p110a subunit) with MMV085400 bound to the active site determined at 2.9 angstroms resolution | Descriptor: | 4-[6-(3,4,5-trimethoxyanilino)pyrazin-2-yl]benzamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | Authors: | Krake, S.H, Martinez, P.D.G, Poggi, M.L, Ferreira, M.S, Aguiar, A.C.C, Souza, G.E, Wenlock, M, Jones, B, Steinbrecher, T, Day, T, McPhail, J, Burke, J, Yeo, T, Mok, S, Uhlemann, A.C, Fidock, D.A, Chen, P, Grodsky, N, Deng, Y.L, Guido, R.V.C, Campbell, S.F, Willis, P.A, Dias, L.C. | Deposit date: | 2021-04-28 | Release date: | 2022-05-04 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Discovery of 2,6-disubstituted pyrazines as potent PI4K inhibitors with antimalarial activity To Be Published
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