5JCB
| Microtubule depolymerizing agent podophyllotoxin derivative YJTSF1 | Descriptor: | (5R,5aR,8aS,9R)-9-[(4H-1,2,4-triazol-3-yl)sulfanyl]-5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydro-2H-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | Authors: | Guan, Z, Zhao, W, Yin, P. | Deposit date: | 2016-04-14 | Release date: | 2017-09-27 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Insights into the Inhibition of Tubulin by the Antitumor Agent 4 beta-(1,2,4-triazol-3-ylthio)-4-deoxypodophyllotoxin. ACS Chem. Biol., 12, 2017
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7YTJ
| Cryo-EM structure of VTC complex | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, INOSITOL HEXAKISPHOSPHATE, PHOSPHATE ION, ... | Authors: | Guan, Z.Y, Chen, J, Liu, R.W, Chen, Y.K, Xing, Q, Du, Z.M, Liu, Z. | Deposit date: | 2022-08-15 | Release date: | 2023-02-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The cytoplasmic synthesis and coupled membrane translocation of eukaryotic polyphosphate by signal-activated VTC complex. Nat Commun, 14, 2023
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7D3T
| Crystal structure of OSPHR2 in complex with DNA | Descriptor: | DNA (5'-D(P*CP*TP*CP*GP*GP*AP*TP*AP*TP*CP*CP*TP*CP*AP*AP*G)-3'), DNA (5'-D(P*GP*CP*TP*TP*GP*AP*GP*GP*AP*TP*AP*TP*CP*CP*GP*A)-3'), Protein PHOSPHATE STARVATION RESPONSE 2 | Authors: | Guan, Z.Y, Zhang, Z.F, Liu, Z. | Deposit date: | 2020-09-20 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
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8J5D
| Cryo-EM structure of starch degradation complex of BAM1-LSF1-MDH | Descriptor: | Beta-amylase 1, chloroplastic, Malate dehydrogenase, ... | Authors: | Guan, Z.Y, Liu, J, Yan, J.J. | Deposit date: | 2023-04-21 | Release date: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The LIKE SEX FOUR 1-malate dehydrogenase complex functions as a scaffold to recruit beta-amylase to promote starch degradation. Plant Cell, 36, 2023
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7D5K
| CryoEM structure of cotton cellulose synthase isoform 7 | Descriptor: | Cellulose synthase, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Guan, Z.Y, Xue, Y, Yin, P, Zhang, X.L. | Deposit date: | 2020-09-26 | Release date: | 2021-07-28 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into homotrimeric assembly of cellulose synthase CesA7 from Gossypium hirsutum. Plant Biotechnol J, 19, 2021
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7CP9
| Cryo-EM structure of human mitochondrial translocase TOM complex at 3.0 angstrom. | Descriptor: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Mitochondrial import receptor subunit TOM22 homolog, Mitochondrial import receptor subunit TOM40 homolog, ... | Authors: | Guan, Z, Yan, L, Wang, Q, Yan, C, Yin, P. | Deposit date: | 2020-08-06 | Release date: | 2021-04-28 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into assembly of human mitochondrial translocase TOM complex. Cell Discov, 7, 2021
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6JG5
| Crystal structure of AimR | Descriptor: | AimR transcriptional regulator | Authors: | Guan, Z.Y, Pei, K, Zou, T.T. | Deposit date: | 2019-02-13 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.221 Å) | Cite: | Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage. Cell Discov, 5, 2019
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6JG9
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6JG8
| Crystal structure of AimR in complex with DNA | Descriptor: | AimR transcriptional regulator, DNA (31-MER) | Authors: | Guan, Z.Y, Pei, K, Zou, T.T. | Deposit date: | 2019-02-13 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.097 Å) | Cite: | Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage. Cell Discov, 5, 2019
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8H0N
| Crystal structure of the human METTL1-WDR4 complex | Descriptor: | tRNA (guanine-N(7)-)-methyltransferase, tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 | Authors: | Jin, X.H, Guan, Z.Y, Gong, Z, Zhang, D.L. | Deposit date: | 2022-09-30 | Release date: | 2023-07-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insight into how WDR4 promotes the tRNA N7-methylguanosine methyltransferase activity of METTL1. Cell Discov, 9, 2023
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7Y77
| Crystal structure of rice NAL1 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Protein NARROW LEAF 1 | Authors: | Yan, J.J, Guan, Z.Y, Yin, P, Xiong, L.Z. | Deposit date: | 2022-06-21 | Release date: | 2023-07-12 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Serine protease NAL1 exerts pleiotropic functions through degradation of TOPLESS-related corepressor in rice. Nat.Plants, 9, 2023
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8W5K
| Cryo-EM structure of the yeast TOM core complex crosslinked by BS3 (from TOM-TIM23 complex) | Descriptor: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, ... | Authors: | Wang, Q, Guan, Z.Y, Zhuang, J.J, Huang, R, Yin, P. | Deposit date: | 2023-08-27 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | The architecture of substrate-engaged TOM-TIM23 supercomplex reveals preprotein proximity sites for mitochondrial protein translocation. Cell Discov, 10, 2024
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8INP
| A reversible glycosyltransferase of tectorigenin - Bc7OUGT | Descriptor: | Bc7OUGT, URIDINE-5'-DIPHOSPHATE, beta-D-glucopyranose | Authors: | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | Deposit date: | 2023-03-10 | Release date: | 2023-08-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence. Plant Biotechnol J, 21, 2023
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8ITA
| A reversible glycosyltransferase of tectorigenin - Bc7OUGT complexed with UDP and tectorigenin | Descriptor: | 3-(4-hydroxyphenyl)-6-methoxy-5,7-bis(oxidanyl)chromen-4-one, Bc7OUGT, URIDINE-5'-DIPHOSPHATE | Authors: | Zhang, Z.Y, Lu, L, Guan, Z.F, Cheng, W.J. | Deposit date: | 2023-03-22 | Release date: | 2023-08-23 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Functional characterization and structural basis of a reversible glycosyltransferase involves in plant chemical defence. Plant Biotechnol J, 21, 2023
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8W5J
| Cryo-EM structure of the yeast TOM core complex (from TOM-TIM23 complex) | Descriptor: | (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl tetradecanoate, Mitochondrial import receptor subunit TOM22, Mitochondrial import receptor subunit TOM40, ... | Authors: | Wang, Q, Guan, Z.Y, Zhuang, J.J, Huang, R, Yin, P. | Deposit date: | 2023-08-27 | Release date: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | The architecture of substrate-engaged TOM-TIM23 supercomplex reveals preprotein proximity sites for mitochondrial protein translocation. Cell Discov, 10, 2024
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8GQE
| Crystal structure of the W285A mutant of UVR8 in complex with RUP2 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Ultraviolet-B receptor UVR8, WD repeat-containing protein RUP2 | Authors: | Wang, Y.D, Wang, L.X, Guan, Z.Y, chang, H.F, Yin, P. | Deposit date: | 2022-08-30 | Release date: | 2022-09-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | RUP2 facilitates UVR8 redimerization via two interfaces. Plant Commun., 4, 2023
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7Y79
| Crystal structure of Cry78Aa | Descriptor: | Toxin | Authors: | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | Deposit date: | 2022-06-21 | Release date: | 2022-08-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7Y78
| Crystal structure of Cry78Aa | Descriptor: | 1,2-ETHANEDIOL, AMMONIUM ION, Toxin | Authors: | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | Deposit date: | 2022-06-21 | Release date: | 2022-08-31 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7YI8
| Cryo-EM structure of SAH-bound MTA1-MTA9-p1-p2 complex | Descriptor: | MT-a70 family protein, MTA9, P1, ... | Authors: | Yan, J.J, Guan, Z.Y, Liu, F.Q, Yan, X.H, Hou, M.J, Yin, P. | Deposit date: | 2022-07-15 | Release date: | 2023-01-18 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into DNA N 6 -adenine methylation by the MTA1 complex. Cell Discov, 9, 2023
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5IL1
| Crystal structure of SAM-bound METTL3-METTL14 complex | Descriptor: | 1,2-ETHANEDIOL, METTL14, METTL3, ... | Authors: | Wang, X, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-04 | Release date: | 2016-05-25 | Last modified: | 2016-06-29 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex Nature, 534, 2016
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5IL0
| Crystal structural of the METTL3-METTL14 complex for N6-adenosine methylation | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, METTL14, ... | Authors: | Wang, X, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-04 | Release date: | 2016-05-25 | Last modified: | 2016-06-29 | Method: | X-RAY DIFFRACTION (1.882 Å) | Cite: | Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex Nature, 534, 2016
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5IL2
| Crystal structure of SAH-bound METTL3-METTL14 complex | Descriptor: | 1,2-ETHANEDIOL, METTL14, METTL3, ... | Authors: | Wang, X, Guan, Z, Zou, T, Yin, P. | Deposit date: | 2016-03-04 | Release date: | 2016-05-25 | Last modified: | 2016-06-29 | Method: | X-RAY DIFFRACTION (1.606 Å) | Cite: | Structural basis of N6-adenosine methylation by the METTL3-METTL14 complex Nature, 534, 2016
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7YI9
| Cryo-EM structure of SAM-bound MTA1-MTA9-p1-p2 complex | Descriptor: | MT-a70 family protein, MTA9, P1, ... | Authors: | Yan, J.J, Guan, Z.Y, Liu, F.Q, Yan, X.H, Hou, M.J, Yin, P. | Deposit date: | 2022-07-15 | Release date: | 2023-01-18 | Last modified: | 2023-08-02 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Structural insights into DNA N 6 -adenine methylation by the MTA1 complex. Cell Discov, 9, 2023
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7D3Y
| Crystal structure of the osPHR2-osSPX2 complex | Descriptor: | INOSITOL HEXAKISPHOSPHATE, Protein PHOSPHATE STARVATION RESPONSE 2, SPX domain-containing protein 2,Isoform 1 of Core histone macro-H2A.1 | Authors: | Zhang, Q.X, Guan, Z.Y, Zuo, J.Q, Zhang, Z.F, Liu, Z. | Deposit date: | 2020-09-21 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.11 Å) | Cite: | Mechanistic insights into the regulation of plant phosphate homeostasis by the rice SPX2 - PHR2 complex. Nat Commun, 13, 2022
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7YFJ
| Crystal structure of human WTAP | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Pre-mRNA-splicing regulator WTAP | Authors: | Yan, X.H, Guan, Z.Y, Tang, C, Yin, P. | Deposit date: | 2022-07-08 | Release date: | 2023-01-25 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | AI-empowered integrative structural characterization of m 6 A methyltransferase complex. Cell Res., 32, 2022
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