7S26
| ROCK1 IN COMPLEX WITH LIGAND G5018 | Descriptor: | 2-[methyl(phenyl)amino]-1-[4-(1H-pyrrolo[2,3-b]pyridin-3-yl)-3,6-dihydropyridin-1(2H)-yl]ethan-1-one, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Rho-associated protein kinase 1 | Authors: | Ganichkin, O, Harris, S.F, Steinbacher, S. | Deposit date: | 2021-09-03 | Release date: | 2022-10-05 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.744 Å) | Cite: | Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors. Nat Commun, 13, 2022
|
|
7S25
| ROCK1 IN COMPLEX WITH LIGAND G4998 | Descriptor: | 2-[3-(methoxymethyl)phenyl]-N-[4-(1H-pyrazol-4-yl)phenyl]acetamide, CHLORIDE ION, Rho-associated protein kinase 1 | Authors: | Ganichkin, O, Harris, S.F, Steinbacher, S. | Deposit date: | 2021-09-03 | Release date: | 2022-10-05 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.337 Å) | Cite: | Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors. Nat Commun, 13, 2022
|
|
6TEO
| Crystal structure of a yeast Snu114-Prp8 complex | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Pre-mRNA-splicing factor 8, ... | Authors: | Ganichkin, O, Jia, J, Loll, B, Absmeier, E, Wahl, M.C. | Deposit date: | 2019-11-12 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | A Snu114-GTP-Prp8 module forms a relay station for efficient splicing in yeast. Nucleic Acids Res., 48, 2020
|
|
2V9V
| Crystal Structure of Moorella thermoacetica SelB(377-511) | Descriptor: | CHLORIDE ION, SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR, SODIUM ION | Authors: | Ganichkin, O, Wahl, M.C. | Deposit date: | 2007-08-27 | Release date: | 2007-09-11 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.1 Å) | Cite: | Conformational Switches in Winged-Helix Domains 1 and 2 of Bacterial Translation Elongation Factor Selb. Acta Crystallogr.,Sect.D, 63, 2007
|
|
6S9A
| Artificial GTPase-BSE dimer of human Dynamin1 | Descriptor: | CHLORIDE ION, Dynamin-1,Dynamin-1, ZINC ION | Authors: | Ganichkin, O.M, Vancraenenbroeck, R, Rosenblum, G, Hofmann, H, Daumke, O, Noel, J.K. | Deposit date: | 2019-07-11 | Release date: | 2020-08-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Quantification and demonstration of the collective constriction-by-ratchet mechanism in the dynamin molecular motor. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|
3BCA
| |
3BC8
| Crystal structure of mouse selenocysteine synthase | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, O-phosphoseryl-tRNA(Sec) selenium transferase | Authors: | Ganichkin, O.M, Wahl, M.C. | Deposit date: | 2007-11-12 | Release date: | 2007-12-18 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structure and catalytic mechanism of eukaryotic selenocysteine synthase. J.Biol.Chem., 283, 2008
|
|
3BCB
| |
7OFV
| NMR-guided design of potent and selective EphA4 agonistic ligands | Descriptor: | ACETATE ION, EphA4 agonist ligand, Ephrin type-A receptor 4 | Authors: | Ganichkin, O.M, Craig, T.K, Baggio, C, Pellecchia, M. | Deposit date: | 2021-05-05 | Release date: | 2021-08-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands. J.Med.Chem., 64, 2021
|
|
3RG5
| Crystal Structure of Mouse tRNA(Sec) | Descriptor: | ACETATE ION, GLYCEROL, SULFATE ION, ... | Authors: | Wahl, M.C, Ganichkin, O.M, Anedchenko, E.A. | Deposit date: | 2011-04-07 | Release date: | 2011-06-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structure analysis reveals functional flexibility in the selenocysteine-specific tRNA from mouse. Plos One, 6, 2011
|
|