6ZCZ
| Crystal structure of receptor binding domain of SARS-CoV-2 Spike glycoprotein in ternary complex with EY6A Fab and a nanobody. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, EY6A heavy chain, ... | Authors: | Zhou, D, Zhao, Y, Fry, E.E, Ren, J, Stuart, D.I. | Deposit date: | 2020-06-12 | Release date: | 2020-06-24 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient. Nat.Struct.Mol.Biol., 27, 2020
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2OHV
| Structural Basis for Glutamate Racemase Inhibition | Descriptor: | (4S)-4-(2-NAPHTHYLMETHYL)-D-GLUTAMIC ACID, Glutamate Racemase | Authors: | Kim, E.E. | Deposit date: | 2007-01-10 | Release date: | 2007-09-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for glutamate racemase inhibition J.Mol.Biol., 372, 2007
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2OKL
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2OEO
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2OHG
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2OS1
| Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes | Descriptor: | ACTINONIN, NICKEL (II) ION, Peptide deformylase, ... | Authors: | Kim, E.E, Kim, K.-H, Moon, J.H, Choi, K, Lee, H.K, Park, H.S. | Deposit date: | 2007-02-05 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes To be Published
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2OS3
| Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes | Descriptor: | ACTINONIN, COBALT (II) ION, Peptide deformylase | Authors: | Kim, E.E, Kim, K.-H, Moon, J.H, Choi, K, Lee, H.K, Parh, H.S. | Deposit date: | 2007-02-05 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.26 Å) | Cite: | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes To be Published
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2OS0
| Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes | Descriptor: | NICKEL (II) ION, Peptide deformylase, SULFATE ION | Authors: | Kim, E.E, Kim, K.-H, Moon, J.H, Choi, K, Lee, H.K, Park, H.S. | Deposit date: | 2007-02-05 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structures of actinonin bound peptide deformylases from E. faecalis and S. pyogenes To be Published
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2P85
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2PRF
| THREE DIMENSIONAL SOLUTION STRUCTURE OF ACANTHAMOEBA PROFILIN I | Descriptor: | PROFILIN IA | Authors: | Archer, S.J, Vinson, V.K, Pollard, T.D, Lattman, E.E, Torchia, D.A. | Deposit date: | 1994-01-12 | Release date: | 1994-05-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Three-dimensional solution structure of Acanthamoeba profilin-I. J.Cell Biol., 122, 1993
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2RNS
| REFINEMENT OF THE CRYSTAL STRUCTURE OF RIBONUCLEASE S. COMPARISON WITH AND BETWEEN THE VARIOUS RIBONUCLEASE A STRUCTURES | Descriptor: | RIBONUCLEASE S, SULFATE ION | Authors: | Kim, E.E, Varadarajan, R, Wyckoff, H.W, Richards, F.M. | Deposit date: | 1992-02-19 | Release date: | 1994-01-31 | Last modified: | 2019-08-14 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Refinement of the crystal structure of ribonuclease S. Comparison with and between the various ribonuclease A structures. Biochemistry, 31, 1992
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2SNM
| IN A STAPHYLOCOCCAL NUCLEASE MUTANT THE SIDE-CHAIN of A LYSINE REPLACING VALINE 66 IS FULLY BURIED IN THE HYDROPHOBIC CORE | Descriptor: | CALCIUM ION, STAPHYLOCOCCAL NUCLEASE, THYMIDINE-3',5'-DIPHOSPHATE | Authors: | Stites, W.E, Gittis, A.G, Lattman, E.E, Shortle, D. | Deposit date: | 1991-04-03 | Release date: | 1993-01-15 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | In a staphylococcal nuclease mutant the side-chain of a lysine replacing valine 66 is fully buried in the hydrophobic core. J.Mol.Biol., 221, 1991
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3NWA
| Glycoprotein B from Herpes simplex virus type 1, W174R mutant, low-pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, MESO-ERYTHRITOL | Authors: | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | Deposit date: | 2010-07-09 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2629 Å) | Cite: | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
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3NWF
| Glycoprotein B from Herpes simplex virus type 1, low-pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein B, MESO-ERYTHRITOL, ... | Authors: | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | Deposit date: | 2010-07-09 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
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3NW8
| Glycoprotein B from Herpes simplex virus type 1, Y179S mutant, high-pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | Deposit date: | 2010-07-09 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.75915 Å) | Cite: | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
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3NWD
| Glycoprotein B from Herpes simplex virus type 1, Y179S mutant, low-pH | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Stampfer, S.D, Lou, H, Cohen, G.H, Eisenberg, R.J, Heldwein, E.E. | Deposit date: | 2010-07-09 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8803 Å) | Cite: | Structural basis of local, pH-dependent conformational changes in glycoprotein B from herpes simplex virus type 1. J.Virol., 84, 2010
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3OIC
| Crystal Structure of Enoyl-ACP Reductases III (FabL) from B. subtilis (apo form) | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADPH], SULFATE ION | Authors: | Kim, K.-H, Ha, B.H, Kim, S.J, Hong, S.K, Hwang, K.Y, Kim, E.E. | Deposit date: | 2010-08-19 | Release date: | 2011-01-05 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis J.Mol.Biol., 406, 2011
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3OJE
| Crystal Structure of the Bacillus cereus Enoyl-Acyl Carrier Protein Reductase (Apo form) | Descriptor: | Enoyl-[acyl-carrier-protein] reductase (FabL) (NADPH) | Authors: | Kim, S.J, Ha, B.H, Kim, K.H, Hong, S.K, Suh, S.W, Kim, E.E. | Deposit date: | 2010-08-22 | Release date: | 2010-09-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (3.02 Å) | Cite: | Dimeric and tetrameric forms of enoyl-acyl carrier protein reductase from Bacillus cereus Biochem.Biophys.Res.Commun., 400, 2010
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3OZ5
| S-Methyl Carbocyclic LNA | Descriptor: | DNA (5'-D(*GP*CP*GP*TP*AP*(UMX)P*AP*CP*GP*C)-3'), SPERMINE | Authors: | Seth, P.R, Allerson, C.A, Berdeja, A, Siwkowski, A, Pallan, P.S, Gaus, H, Prakash, T.P, Watt, A.T, Egli, M, Swayze, E.E. | Deposit date: | 2010-09-24 | Release date: | 2010-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. J.Am.Chem.Soc., 132, 2010
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3OQC
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3OID
| Crystal Structure of Enoyl-ACP Reductases III (FabL) from B. subtilis (complex with NADP and TCL) | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRICLOSAN | Authors: | Kim, K.-H, Ha, B.H, Kim, S.J, Hong, S.K, Hwang, K.Y, Kim, E.E. | Deposit date: | 2010-08-19 | Release date: | 2011-01-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis J.Mol.Biol., 406, 2011
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3OZ3
| Vinyl Carbocyclic LNA | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*(UVX)P*AP*CP*GP*C)-3') | Authors: | Seth, P.R, Allerson, C.A, Berdeja, A, Siwkowski, A, Pallan, P.S, Gaus, H, Prakash, T.P, Watt, A.T, Egli, M, Swayze, E.E. | Deposit date: | 2010-09-24 | Release date: | 2010-11-24 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.57 Å) | Cite: | An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. J.Am.Chem.Soc., 132, 2010
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3OIF
| Crystal Structure of Enoyl-ACP Reductases I (FabI) from B. subtilis (complex with NAD and TCL) | Descriptor: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | Authors: | Kim, K.-H, Ha, B.H, Kim, S.J, Hong, S.K, Hwang, K.Y, Kim, E.E. | Deposit date: | 2010-08-19 | Release date: | 2011-01-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal Structures of Enoyl-ACP Reductases I (FabI) and III (FabL) from B. subtilis J.Mol.Biol., 406, 2011
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7M17
| SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-1) | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 7-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}heptanoic acid, Volume-regulated anion channel subunit LRRC8A | Authors: | Kern, D.M, Gerber, E.E, Brohawn, S.G. | Deposit date: | 2021-03-12 | Release date: | 2021-03-24 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes. Nat Commun, 13, 2022
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7M19
| SN-407-LRRC8A in MSP1E3D1 lipid nanodiscs (Pose-2) | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 7-{[(2S)-2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl]oxy}heptanoic acid, Volume-regulated anion channel subunit LRRC8A | Authors: | Kern, D.M, Gerber, E.E, Brohawn, S.G. | Deposit date: | 2021-03-12 | Release date: | 2021-03-24 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.69 Å) | Cite: | Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes. Nat Commun, 13, 2022
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