1KMZ
 
 | | MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE | | Descriptor: | mitomycin-binding protein | | Authors: | Martin, T.W, Dauter, Z, Devedjiev, Y, Sheffield, P, Jelen, F, He, M, Sherman, D, Otlewski, J, Derewenda, Z.S, Derewenda, U. | | Deposit date: | 2001-12-17 | | Release date: | 2002-07-19 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
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3FHK
 | | Crystal structure of APC1446, B.subtilis YphP disulfide isomerase | | Descriptor: | SULFATE ION, UPF0403 protein yphP | | Authors: | Derewenda, U, Boczek, T, Cooper, D.R, Yu, M, Hung, L, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2008-12-09 | | Release date: | 2009-09-01 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure and function of Bacillus subtilis YphP, a prokaryotic disulfide isomerase with a CXC catalytic motif .
Biochemistry, 48, 2009
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3HD0
 | | Crystal structure of Tm1865, an Endonuclease V from Thermotoga Maritima | | Descriptor: | Endonuclease V | | Authors: | Utepbergenov, D, Cooper, D.R, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2009-05-06 | | Release date: | 2009-07-14 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of Tm1865, an Endonuclease V from Thermotoga Maritima
To be Published
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1KLL
 | | Molecular basis of mitomycin C resictance in streptomyces: Crystal structures of the MRD protein with and without a drug derivative | | Descriptor: | 1,2-CIS-1-HYDROXY-2,7-DIAMINO-MITOSENE, mitomycin-binding protein | | Authors: | Martin, T.W, Dauter, Z, Devedjiev, Y, Sheffield, P, Jelen, F, He, M, Sherman, D, Otlewski, J, Derewenda, Z.S, Derewenda, U. | | Deposit date: | 2001-12-12 | | Release date: | 2002-07-19 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein.
Structure, 10, 2002
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1KTJ
 | | X-ray Structure Of Der P 2, The Major House Dust Mite Allergen | | Descriptor: | ALLERGEN DER P 2 | | Authors: | Derewenda, U, Li, J, Derewenda, Z, Dauter, Z, Mueller, G.A, Rule, G.S, Benjamin, D.C. | | Deposit date: | 2002-01-16 | | Release date: | 2002-05-15 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The crystal structure of a major dust mite allergen Der p 2, and its biological implications.
J.Mol.Biol., 318, 2002
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1YBO
 | | Crystal structure of the PDZ tandem of human syntenin with syndecan peptide | | Descriptor: | Syndecan-4, Syntenin 1 | | Authors: | Grembecka, J, Cooper, D.R, Cierpicki, T, Kang, B.S, Devedjiev, Y, Derewenda, Z. | | Deposit date: | 2004-12-21 | | Release date: | 2006-01-10 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | The binding of the PDZ tandem of syntenin to target proteins
Biochemistry, 45, 2006
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1N99
 | | CRYSTAL STRUCTURE OF THE PDZ TANDEM OF HUMAN SYNTENIN | | Descriptor: | Syntenin 1 | | Authors: | Kang, B.S, Cooper, D.R, Jelen, F, Devedjiev, Y, Derewenda, U, Dauter, Z, Otlewski, J, Derewenda, Z.S. | | Deposit date: | 2002-11-22 | | Release date: | 2003-04-15 | | Last modified: | 2022-12-21 | | Method: | X-RAY DIFFRACTION (1.94 Å) | | Cite: | PDZ Tandem of Human Syntenin: Crystal Structure and Functional Properties
Structure, 11, 2003
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1TIA
 | | AN UNUSUAL BURIED POLAR CLUSTER IN A FAMILY OF FUNGAL LIPASES | | Descriptor: | LIPASE | | Authors: | Derewenda, U, Swenson, L, Yamaguchi, S, Wei, Y, Derewenda, Z.S. | | Deposit date: | 1993-12-06 | | Release date: | 1995-01-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | An unusual buried polar cluster in a family of fungal lipases.
Nat.Struct.Biol., 1, 1994
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1W9E
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFYF peptide | | Descriptor: | BENZOIC ACID, SYNTENIN 1, TNEFYF PEPTIDE | | Authors: | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2004-10-09 | | Release date: | 2006-03-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.56 Å) | | Cite: | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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1W9O
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYYV peptide | | Descriptor: | BENZOIC ACID, SYNTENIN 1, TNEYYV PEPTIDE | | Authors: | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2004-10-15 | | Release date: | 2006-03-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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1XAS
 | | CRYSTAL STRUCTURE, AT 2.6 ANGSTROMS RESOLUTION, OF THE STREPTOMYCES LIVIDANS XYLANASE A, A MEMBER OF THE F FAMILY OF BETA-1,4-D-GLYCANSES | | Descriptor: | 1,4-BETA-D-XYLAN XYLANOHYDROLASE | | Authors: | Derewenda, U, Derewenda, Z.S. | | Deposit date: | 1994-05-31 | | Release date: | 1995-05-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure, at 2.6-A resolution, of the Streptomyces lividans xylanase A, a member of the F family of beta-1,4-D-glycanases.
J.Biol.Chem., 269, 1994
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3T06
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3UBD
 | | Structure of N-terminal domain of RSK2 kinase in complex with flavonoid glycoside SL0101 | | Descriptor: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 3,4-di-O-acetyl-6-deoxy-alpha-L-mannopyranoside, Ribosomal protein S6 kinase alpha-3 | | Authors: | Utepbergenov, D, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2011-10-24 | | Release date: | 2012-09-05 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.53 Å) | | Cite: | Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor.
Biochemistry, 51, 2012
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1FTN
 | | CRYSTAL STRUCTURE OF THE HUMAN RHOA/GDP COMPLEX | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, TRANSFORMING PROTEIN RHOA (H12) | | Authors: | Wei, Y, Zhang, Y, Derewenda, U, Liu, X, Minor, W, Nakamoto, R.K, Somlyo, A.V, Somlyo, A.P, Derewenda, Z.S. | | Deposit date: | 1997-03-13 | | Release date: | 1998-03-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal structure of RhoA-GDP and its functional implications.
Nat.Struct.Biol., 4, 1997
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3SXM
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3SXY
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3SXZ
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3SXK
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1JKM
 | | BREFELDIN A ESTERASE, A BACTERIAL HOMOLOGUE OF HUMAN HORMONE SENSITIVE LIPASE | | Descriptor: | BREFELDIN A ESTERASE | | Authors: | Wei, Y, Contreras, A.J, Sheffield, P, Osterlund, T, Derewenda, U, Matern, U.O, Derewenda, Z.S. | | Deposit date: | 1998-02-04 | | Release date: | 1999-02-16 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Crystal structure of brefeldin A esterase, a bacterial homolog of the mammalian hormone-sensitive lipase.
Nat.Struct.Biol., 6, 1999
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1OBX
 | | Crystal structure of the complex of PDZ2 of syntenin with an interleukin 5 receptor alpha peptide. | | Descriptor: | COBALT (II) ION, INTERLEUKIN 5 RECEPTOR ALPHA, SULFATE ION, ... | | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-01-31 | | Release date: | 2003-07-10 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
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1W9Q
 | | Crystal structure of the PDZ tandem of human syntenin in complex with TNEFAF peptide | | Descriptor: | BENZOIC ACID, SYNTENIN 1, TNEFAF PEPTIDE | | Authors: | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, Z.S. | | Deposit date: | 2004-10-15 | | Release date: | 2006-03-22 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The Binding of the Pdz Tandem of Syntenin to Target Proteins.
Biochemistry, 45, 2006
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3H3E
 | | Crystal structure of Tm1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY | | Descriptor: | ZINC ION, uncharacterized protein Tm1679 | | Authors: | Cooper, D.R, Olekhnovitch, N, Derewenda, U, Derewenda, Z.S, Integrated Center for Structure and Function Innovation (ISFI) | | Deposit date: | 2009-04-16 | | Release date: | 2009-07-14 | | Last modified: | 2021-10-13 | | Method: | X-RAY DIFFRACTION (2.749 Å) | | Cite: | Crystal structure of Tm1679, A METAL-DEPENDENT HYDROLASE OF THE BETA-LACTAMASE SUPERFAMILY
To be Published
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1FJ2
 | | Crystal structure of the human acyl protein thioesterase 1 at 1.5 A resolution | | Descriptor: | BROMIDE ION, PROTEIN (ACYL PROTEIN THIOESTERASE 1) | | Authors: | Devedjiev, Y, Dauter, Z, Kuznetsov, S, Jones, T, Derewenda, Z. | | Deposit date: | 2000-08-07 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of the human acyl protein thioesterase I from a single X-ray data set to 1.5 A.
Structure Fold.Des., 8, 2000
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1H4R
 | | Crystal Structure of the FERM domain of Merlin, the Neurofibromatosis 2 Tumor Suppressor Protein. | | Descriptor: | MERLIN, SULFATE ION | | Authors: | Cooper, D.R, Kang, B.S, Sheffield, P, Devedjiev, Y, Derewenda, Z.S. | | Deposit date: | 2001-05-14 | | Release date: | 2002-01-16 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | The Structure of the Ferm Domain of Merlin, the Neurofibromatosis Type 2 Gene Product.
Acta Crystallogr.,Sect.D, 58, 2002
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1OBY
 | | Crystal structure of the complex of PDZ2 of syntenin with a syndecan-4 peptide. | | Descriptor: | SULFATE ION, SYNDECAN-4, SYNTENIN 1 | | Authors: | Kang, B.S, Cooper, D.R, Devedjiev, Y, Derewenda, U, Derewenda, Z.S. | | Deposit date: | 2003-01-31 | | Release date: | 2003-07-11 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Molecular Roots of Degenerate Specificity in Syntenin'S Pdz2 Domain: Reassessment of the Pdz Recognition Paradigm
Structure, 11, 2003
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