1WPD
 
 | | Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins | | Descriptor: | Potassium channel toxin alpha-KTx 6.2,Potassium channel toxin alpha-KTx 6.3 | | Authors: | Regaya, I, Beeton, C, Ferrat, G, Andreotti, N, Chandy, G.K, Darbon, H, De Waard, M, Sabatier, J.M. | | Deposit date: | 2004-09-01 | | Release date: | 2004-10-19 | | Last modified: | 2019-12-18 | | Method: | SOLUTION NMR | | Cite: | Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins
J.Biol.Chem., 279, 2004
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1WQE
 | | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | | Descriptor: | OmTx3 | | Authors: | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | | Deposit date: | 2004-09-28 | | Release date: | 2005-01-18 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
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1WT7
 | | Solution structure of BuTX-MTX: a butantoxin-maurotoxin chimera | | Descriptor: | BuTX-MTX | | Authors: | M'Barek, S, Chagot, B, Andreotti, N, Visan, V, Mansuelle, P, Grissmer, S, Marrakchi, M, El Ayeb, M, Sampieri, F, Darbon, H, Fajloun, Z, De Waard, M, Sabatier, J.-M. | | Deposit date: | 2004-11-16 | | Release date: | 2004-11-30 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Increasing the molecular contacts between maurotoxin and Kv1.2 channel augments ligand affinity.
Proteins, 60, 2005
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1WQC
 | | An unusual fold for potassium channel blockers : NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | | Descriptor: | OmTx1 | | Authors: | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | | Deposit date: | 2004-09-27 | | Release date: | 2005-01-18 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
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1HLY
 | | SOLUTION STRUCTURE OF HONGOTOXIN 1 | | Descriptor: | HONGOTOXIN 1 | | Authors: | Pragl, B, Koschak, A, Trieb, M, Obermair, G, Kaufmann, W.A, Gerster, U, Blanc, E, Hahn, C, Prinz, H, Schutz, G, Darbon, H, Gruber, H.J, Knaus, H.G. | | Deposit date: | 2000-12-04 | | Release date: | 2003-09-30 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Synthesis, characterization, and application of cy-dye- and alexa-dye-labeled hongotoxin(1) analogues. The
first high affinity fluorescence probes for voltage-gated K+ channels.
BIOCONJUG.CHEM., 13, 2002
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2Z3S
 | | NMR structure of AgTx2-MTX | | Descriptor: | AgTx2-MTX | | Authors: | Pimentel, C, M'Barrek, S, Visan, V, Grissmer, S, Sabatier, J.M, Darbon, H, Fajloun, Z. | | Deposit date: | 2007-06-06 | | Release date: | 2008-04-22 | | Last modified: | 2020-02-26 | | Method: | SOLUTION NMR | | Cite: | Chemical synthesis and 1H-NMR 3D structure determination of AgTx2-MTX chimera, a new potential blocker for Kv1.2 channel, derived from MTX and AgTx2 scorpion toxins.
Protein Sci., 17, 2008
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1Q01
 | | Lebetin peptides, a new class of potent aggregation inhibitors | | Descriptor: | lebetin 2 isoform alpha | | Authors: | Mosbah, A, Marrakchi, N, Ganzalez, M.J, Van Rietschoten, J, Giralt, E, El Ayeb, M, Rochat, H, Sabatier, J.M, Darbon, H, Mabrouk, K. | | Deposit date: | 2003-07-15 | | Release date: | 2005-05-03 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Lebetin peptides, a new class of potent aggregation inhibitors
To be Published
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1G9E
 | | SOLUTION STRUCTURE AND RELAXATION MEASUREMENTS OF AN ANTIGEN-FREE HEAVY CHAIN VARIABLE DOMAIN (VHH) FROM LLAMA | | Descriptor: | H14 | | Authors: | Renisio, J.-G, Perez, J, Czisch, M, Guenneugues, M, Bornet, O, Frenken, L, Cambillau, C, Darbon, H. | | Deposit date: | 2000-11-23 | | Release date: | 2002-10-23 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure and backbone dynamics of an antigen-free heavy chain variable
domain (VHH) from Llama
Proteins, 47, 2002
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2KGH
 | | Solution structure of Brachyperma ruhnaui toxin 2 | | Descriptor: | Venom peptide 2 | | Authors: | Corzo, G, Bernard, C, Clement, H, Bosmans, F, Tygat, J, Possani, L.D, Darbon, H, Alagon, A. | | Deposit date: | 2009-03-12 | | Release date: | 2009-12-15 | | Last modified: | 2022-03-16 | | Method: | SOLUTION NMR | | Cite: | Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2.
Biochim.Biophys.Acta, 1794, 2009
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2CK5
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2BMT
 | | SCORPION TOXIN BMTX2 FROM BUTHUS MARTENSII KARSCH, NMR, 25 STRUCTURES | | Descriptor: | TOXIN BMTX2 | | Authors: | Blanc, E, Romi-Lebrun, R, Bornet, O, Nakajima, T, Darbon, H. | | Deposit date: | 1998-06-16 | | Release date: | 1999-01-13 | | Last modified: | 2019-12-25 | | Method: | SOLUTION NMR | | Cite: | Solution structure of two new toxins from the venom of the Chinese scorpion Buthus martensi Karsch blockers of potassium channels.
Biochemistry, 37, 1998
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2CK4
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1NCV
 | | DETERMINATION CC-CHEMOKINE MCP-3, NMR, 7 STRUCTURES | | Descriptor: | MONOCYTE CHEMOATTRACTANT PROTEIN 3 | | Authors: | Meunier, S, Bernassau, J.M, Guillemot, J.C, Ferrara, P, Darbon, H. | | Deposit date: | 1997-02-05 | | Release date: | 1997-10-15 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Determination of the three-dimensional structure of CC chemokine monocyte chemoattractant protein 3 by 1H two-dimensional NMR spectroscopy.
Biochemistry, 36, 1997
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1PNH
 | | SOLUTION STRUCTURE OF PO5-NH2, A SCORPION TOXIN ANALOG WITH HIGH AFFINITY FOR THE APAMIN-SENSITIVE POTASSIUM CHANNEL | | Descriptor: | SCORPION TOXIN | | Authors: | Meunier, S, Bernassau, J.-M, Sabatier, J.-M, Martin-Eauclaire, M.-F, Van Rietschoten, J, Cambillau, C, Darbon, H. | | Deposit date: | 1993-08-25 | | Release date: | 1994-01-31 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | Solution structure of P05-NH2, a scorpion toxin analog with high affinity for the apamin-sensitive potassium channel.
Biochemistry, 32, 1993
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1K19
 | | NMR Solution Structure of the Chemosensory Protein CSP2 from Moth Mamestra brassicae | | Descriptor: | Chemosensory Protein CSP2 | | Authors: | Mosbah, A, Campanacci, V, Lartigue, A, Tegoni, M, Cambillau, C, Darbon, H. | | Deposit date: | 2001-09-24 | | Release date: | 2002-12-04 | | Last modified: | 2022-02-23 | | Method: | SOLUTION NMR | | Cite: | Solution structure of a chemosensory protein from the moth Mamestra brassicae
BIOCHEM.J., 369, 2003
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1WQK
 | | Solution structure of APETx1, a specific peptide inhibitor of human Ether-a-go-go-related gene potassium channels from the venom of the sea anemone Anthopleura elegantissima: a new fold for an HERG toxin | | Descriptor: | Toxin APETx1 | | Authors: | Chagot, B, Diochot, S, Pimentel, C, Lazdunski, M, Darbon, H. | | Deposit date: | 2004-09-30 | | Release date: | 2005-03-08 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of APETx1 from the sea anemone Anthopleura elegantissima: A new fold for an HERG toxin
Proteins, 59, 2005
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1WXN
 | | Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels | | Descriptor: | Toxin APETx2 | | Authors: | Chagot, B, Escoubas, P, Diochot, S, Bernard, C, Lazdunski, M, Darbon, H. | | Deposit date: | 2005-01-27 | | Release date: | 2005-08-16 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
Protein Sci., 14, 2005
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1WO9
 | | Selective inhibition of trypsins by insect peptides: role of P6-P10 loop | | Descriptor: | trypsin inhibitor | | Authors: | Kellenberger, C, Ferrat, G, Leone, P, Darbon, H, Roussel, A. | | Deposit date: | 2004-08-12 | | Release date: | 2004-09-07 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Selective inhibition of trypsins by insect peptides: role of P6-P10 loop
Biochemistry, 42, 2003
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1X5V
 | | NMR Structure of PcFK1 | | Descriptor: | PcFK1 | | Authors: | Pimentel, C, Choi, S.J, Chagot, B, Guette, C, Camadro, J.M, Darbon, H. | | Deposit date: | 2005-05-17 | | Release date: | 2006-04-04 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of PcFK1, a spider peptide active against Plasmodium falciparum
Protein Sci., 15, 2006
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1WQD
 | | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis | | Descriptor: | OmTx2 | | Authors: | Chagot, B, Pimentel, C, Dai, L, Pil, J, Tytgat, J, Nakajima, T, Corzo, G, Darbon, H, Ferrat, G. | | Deposit date: | 2004-09-28 | | Release date: | 2005-01-18 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | An unusual fold for potassium channel blockers: NMR structure of three toxins from the scorpion Opisthacanthus madagascariensis
Biochem.J., 388, 2005
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1Y2P
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1TXM
 | | SCORPION TOXIN (MAUROTOXIN) FROM SCORPIO MAURUS, NMR, 35 STRUCTURES | | Descriptor: | MAUROTOXIN | | Authors: | Blanc, E, Sabatier, J.-M, Kharrat, R, Meunier, S, El Ayeb, M, Van Rietschoten, J, Darbon, H. | | Deposit date: | 1996-11-19 | | Release date: | 1997-06-05 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels.
Proteins, 29, 1997
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1TSK
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1V90
 | | Solution structure by NMR means of delta-paluIT1-NH2 | | Descriptor: | Delta-palutoxin IT1 | | Authors: | Ferrat, G, Bosmans, F, Tytgat, J, Pimentel, C, Chagot, B, Nakajima, T, Darbon, H, Corzo, G. | | Deposit date: | 2004-01-19 | | Release date: | 2005-03-29 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel
Proteins, 59, 2005
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1V91
 | | Solution structure of insectidal toxin delta-paluIT2-NH2 | | Descriptor: | Delta-palutoxin IT2 | | Authors: | Ferrat, G, Bosmans, F, Tytgat, J, Pimentel, C, Chagot, B, Nakajima, T, Darbon, H, Corzo, G. | | Deposit date: | 2004-01-19 | | Release date: | 2005-03-29 | | Last modified: | 2023-12-27 | | Method: | SOLUTION NMR | | Cite: | Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel
Proteins, 59, 2005
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