6WI7
| RING1B-BMI1 fusion in closed conformation | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, E3 ubiquitin-protein ligase RING2, Polycomb complex protein BMI-1 chimera, ... | Authors: | Cho, H.J, Cierpicki, T. | Deposit date: | 2020-04-08 | Release date: | 2021-04-14 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.702 Å) | Cite: | Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain. Nat.Chem.Biol., 17, 2021
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6WI8
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2QHB
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8CHO
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6KQP
| NSD1 SET domain in complex with SAM | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific, S-ADENOSYLMETHIONINE, ... | Authors: | Cho, H.J, Cierpicki, T. | Deposit date: | 2019-08-18 | Release date: | 2020-09-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Covalent inhibition of NSD1 histone methyltransferase. Nat.Chem.Biol., 16, 2020
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6LFK
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8GTI
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL | Descriptor: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, ... | Authors: | Cho, H.S, Kim, H. | Deposit date: | 2022-09-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
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8GTM
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL | Descriptor: | 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | Authors: | Cho, H.S, Kim, H. | Deposit date: | 2022-09-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
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8GTG
| Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-I-152 by XFEL | Descriptor: | 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N},~{N}-bis(2-methoxyethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 | Authors: | Cho, H.S, Kim, H. | Deposit date: | 2022-09-08 | Release date: | 2023-09-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
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5YZI
| Crystal Structure of Mouse Cytosolic Isocitrate Dehydrogenase complexed with Cadmium | Descriptor: | CADMIUM ION, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Cho, H.J, Kang, B.S. | Deposit date: | 2017-12-14 | Release date: | 2018-07-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.519 Å) | Cite: | NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione. J. Biol. Inorg. Chem., 23, 2018
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5YZH
| Crystal Structure of Mouse Cytosolic Isocitrate Dehydrogenase | Descriptor: | GLYCEROL, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Cho, H.J, Kang, B.S. | Deposit date: | 2017-12-14 | Release date: | 2018-07-04 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.994 Å) | Cite: | NADP+-dependent cytosolic isocitrate dehydrogenase provides NADPH in the presence of cadmium due to the moderate chelating effect of glutathione. J. Biol. Inorg. Chem., 23, 2018
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7XFP
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2WL9
| Crystal structure of catechol 2,3-dioxygenase | Descriptor: | 3-METHYLCATECHOL, CATECHOL 2,3-DIOXYGENASE, FE (III) ION, ... | Authors: | Cho, H.J, Kim, K.J, Kang, B.S. | Deposit date: | 2009-06-23 | Release date: | 2010-09-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Substrate-Binding Mechanism of a Type I Extradiol Dioxygenase. J.Biol.Chem., 285, 2010
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2WL3
| crystal structure of catechol 2,3-dioxygenase | Descriptor: | CALCIUM ION, CATECHOL 2,3-DIOXYGENASE, FE (III) ION, ... | Authors: | Cho, H.J, Kim, K.J, Kang, B.S. | Deposit date: | 2009-06-21 | Release date: | 2010-09-01 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Substrate-Binding Mechanism of a Type I Extradiol Dioxygenase. J.Biol.Chem., 285, 2010
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8OHM
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5A34
| The crystal structure of the GST-like domains complex of EPRS-AIMP2 | Descriptor: | AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2, BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE, GLYCEROL | Authors: | Cho, H.Y, Kang, B.S. | Deposit date: | 2015-05-27 | Release date: | 2015-10-21 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Assembly of Multi-tRNA Synthetase Complex Via Heterotetrameric Glutathione Transferase-Homology Domains. J.Biol.Chem., 290, 2015
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5BMU
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4BVX
| Crystal structure of the AIMP3-MRS N-terminal domain complex with I3C | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1, METHIONINE--TRNA LIGASE, ... | Authors: | Cho, H.Y, Seo, W.W, Cho, H.J, Kang, B.S. | Deposit date: | 2013-06-29 | Release date: | 2014-07-16 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Assembly of Multi-tRNA Synthetase Complex Via Heterotetrameric Glutathione Transferase-Homology Domains. J.Biol.Chem., 290, 2015
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3ZXO
| CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS | Descriptor: | ACETATE ION, GLYCEROL, REDOX SENSOR HISTIDINE KINASE RESPONSE REGULATOR DEVS, ... | Authors: | Cho, H.Y, Cho, H.J, Kang, B.S. | Deposit date: | 2011-08-13 | Release date: | 2011-08-24 | Last modified: | 2013-05-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Activation of ATP Binding for the Autophosphorylation of Doss, a Mycobacterium Tuberculosis Histidine Kinase Lacking an ATP-Lid Motif. J.Biol.Chem., 288, 2013
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3ZXQ
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7W9Z
| Crystal structure of Bacillus subtilis YugJ in complex with NADP and nitrate | Descriptor: | Iron-containing alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NITRATE ION | Authors: | Cho, H.Y, Nam, M.S, Hong, H.J, Song, W.S, Yoon, S.I. | Deposit date: | 2021-12-11 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural and Biochemical Analysis of the Furan Aldehyde Reductase YugJ from Bacillus subtilis. Int J Mol Sci, 23, 2022
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7W9Y
| Crystal structure of Bacillus subtilis YugJ in complex with NADP and nickel | Descriptor: | Iron-containing alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICKEL (II) ION | Authors: | Cho, H.Y, Nam, M.S, Hong, H.J, Song, W.S, Yoon, S.I. | Deposit date: | 2021-12-11 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Structural and Biochemical Analysis of the Furan Aldehyde Reductase YugJ from Bacillus subtilis. Int J Mol Sci, 23, 2022
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7W9X
| Crystal structure of Bacillus subtilis YugJ in complex with nickel | Descriptor: | Iron-containing alcohol dehydrogenase, NICKEL (II) ION | Authors: | Cho, H.Y, Nam, M.S, Hong, H.J, Song, W.S, Yoon, S.I. | Deposit date: | 2021-12-11 | Release date: | 2022-12-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Structural and Biochemical Analysis of the Furan Aldehyde Reductase YugJ from Bacillus subtilis. Int J Mol Sci, 23, 2022
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4BVY
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4BL7
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