2Q9Q
| The crystal structure of full length human GINS complex | Descriptor: | DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ... | Authors: | Chang, Y.P, Wang, G, Chen, X.S. | Deposit date: | 2007-06-13 | Release date: | 2007-08-07 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Crystal structure of the GINS complex and functional insights into its role in DNA replication. Proc.Natl.Acad.Sci.Usa, 104, 2007
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7VF4
| Crystal structure of Vps75 from Candida albicans | Descriptor: | CHLORIDE ION, SODIUM ION, Vps75 | Authors: | Wang, W, Chen, X, Yang, Z, Chen, X, Li, C, Wang, M. | Deposit date: | 2021-09-10 | Release date: | 2021-10-06 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal structure of histone chaperone Vps75 from Candida albicans. Biochem.Biophys.Res.Commun., 578, 2021
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7XS3
| AlXyn26A E243A-X3X4X | Descriptor: | AlXyn26A E243A-X3X4X, beta-D-xylopyranose-(1-3)-beta-D-xylopyranose-(1-4)-beta-D-xylopyranose | Authors: | Zhang, Y.Z, Chen, X.L, Zhao, F, Yu, C.M. | Deposit date: | 2022-05-12 | Release date: | 2023-05-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | A novel class of xylanases specifically degrade marine red algal beta 1,3/1,4-mixed-linkage xylan. J.Biol.Chem., 299, 2023
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7CN9
| Cryo-EM structure of SARS-CoV-2 Spike ectodomain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Ho, M, Chang, Y, Wang, C, Wu, Y, Huang, H, Chen, T, Lo, J.M, Chen, X, Ma, C. | Deposit date: | 2020-07-30 | Release date: | 2020-08-26 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (4.7 Å) | Cite: | A Carbohydrate-Binding Protein from the Edible Lablab Beans Effectively Blocks the Infections of Influenza Viruses and SARS-CoV-2. Cell Rep, 32, 2020
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7C8G
| Structure of alginate lyase AlyC3 | Descriptor: | Alginate lyase AlyC3, GLYCEROL, SUCCINIC ACID | Authors: | Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P. | Deposit date: | 2020-05-30 | Release date: | 2020-10-07 | Last modified: | 2020-12-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic. J.Biol.Chem., 295, 2020
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7C8F
| Structure of alginate lyase AlyC3 in complex with dimannuronate(2M) | Descriptor: | H127A/Y244A mutant of alginate lyase AlyC3 in complex with dimannuronate, MALONATE ION, beta-D-mannopyranuronic acid-(1-4)-beta-D-mannopyranuronic acid | Authors: | Zhang, Y.Z, Xu, F, Chen, X.L, Wang, P. | Deposit date: | 2020-05-30 | Release date: | 2020-10-07 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.461 Å) | Cite: | Structural and molecular basis for the substrate positioning mechanism of a new PL7 subfamily alginate lyase from the arctic. J.Biol.Chem., 295, 2020
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6IZK
| Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus | Descriptor: | CHLORIDE ION, IMIDAZOLE, L(+)-TARTARIC ACID, ... | Authors: | Sangare, L, Chen, W, Wang, C, Chen, X, Wu, M, Zhang, X, Zang, J. | Deposit date: | 2018-12-19 | Release date: | 2020-01-22 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Structural characterization of mutated NreA protein in nitrate binding site from Staphylococcus aureus To Be Published
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6JQF
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2JQQ
| Solution structure of Saccharomyces cerevisiae conserved oligomeric Golgi subunit 2 protein (Cog2p) | Descriptor: | Conserved oligomeric Golgi complex subunit 2 | Authors: | Cavanaugh, L.F, Chen, X, Pelczer, I, Rizo, J, Hughson, F.M. | Deposit date: | 2007-06-06 | Release date: | 2007-06-19 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structural analysis of conserved oligomeric Golgi complex subunit 2 J.Biol.Chem., 282, 2007
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4R83
| Crystal structure of Sialyltransferase from Photobacterium damsela | Descriptor: | CALCIUM ION, Sialyltransferase 0160 | Authors: | Fisher, A.J, Chen, X, Li, Y, Huynh, N. | Deposit date: | 2014-08-29 | Release date: | 2014-12-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structures of sialyltransferase from Photobacterium damselae. Febs Lett., 588, 2014
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7YGI
| Crystal structure of p53 DBD domain in complex with azurin | Descriptor: | Azurin, Cellular tumor antigen p53, PHOSPHATE ION, ... | Authors: | Jiang, W.X, Zuo, J.Q, Hu, J.J, Chen, X.Q, Ma, L.X, Liu, Z, Xing, Q. | Deposit date: | 2022-07-11 | Release date: | 2023-02-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of bacterial effector protein azurin targeting tumor suppressor p53 and inhibiting its ubiquitination. Commun Biol, 6, 2023
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7FAT
| Structure Determination of the RBD-NB1A7 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, nb_1A7 | Authors: | Geng, Y, Shi, Z.Z, Li, X.Y, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C. | Deposit date: | 2021-07-07 | Release date: | 2022-05-18 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural basis of nanobodies neutralizing SARS-CoV-2 variants Structure, 30, 2022
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7FAU
| Structure Determination of the NB1B11-RBD Complex | Descriptor: | NB_1B11, Spike protein S1, ZINC ION | Authors: | Shi, Z.Z, Li, X.X, Wang, L, Sun, Z.C, Zhang, H.W, Chen, X.C, Cui, Q.Q, Qiao, H.R, Lan, Z.Y, Zhang, X. | Deposit date: | 2021-07-07 | Release date: | 2022-06-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural basis of nanobodies neutralizing SARS-CoV-2 variants. Structure, 30, 2022
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4R9V
| Crystal structure of sialyltransferase from photobacterium damselae, residues 113-497 corresponding to the gt-b domain | Descriptor: | CALCIUM ION, Sialyltransferase 0160 | Authors: | Li, Y, Huynh, N, Chen, X, Fisher, A.J. | Deposit date: | 2014-09-08 | Release date: | 2014-12-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of sialyltransferase from Photobacterium damselae. Febs Lett., 588, 2014
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4R84
| Crystal structure of Sialyltransferase from Photobacterium damsela with CMP-3F(a)Neu5Ac bound | Descriptor: | CALCIUM ION, CYTIDINE-5'-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC ACID, Sialyltransferase 0160 | Authors: | Fisher, A.J, Chen, X, Li, Y, Huynh, N. | Deposit date: | 2014-08-29 | Release date: | 2014-12-03 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal structures of sialyltransferase from Photobacterium damselae. Febs Lett., 588, 2014
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2KVT
| solution NMR structure of yaiA from Escherichia Eoli. Northeast Structural Genomics Target ER244 | Descriptor: | Uncharacterized protein yaiA | Authors: | Tang, Y, Chen, X, Ciccosanti, C, Janjua, H, Xiao, R, Acton, T, Everett, J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-03-28 | Release date: | 2010-05-19 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | solution NMR structure of yaiA from Escherichia coli. Northeast Structural Genomics Target ER244 To be Published
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7E6T
| Structural insights into the activation of human calcium-sensing receptor | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYCLOMETHYLTRYPTOPHAN, ... | Authors: | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | Deposit date: | 2021-02-24 | Release date: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the activation of human calcium-sensing receptor. Elife, 10, 2021
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7E6U
| the complex of inactive CaSR and NB2D11 | Descriptor: | Extracellular calcium-sensing receptor, NB-2D11 | Authors: | Geng, Y, Chen, X.C, Wang, L, Cui, Q.Q, Ding, Z.Y, Han, L, Kou, Y.J, Zhang, W.Q, Wang, H.N, Jia, X.M, Dai, M, Shi, Z.Z, Li, Y.Y, Li, X.Y. | Deposit date: | 2021-02-24 | Release date: | 2021-09-22 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Structural insights into the activation of human calcium-sensing receptor. Elife, 10, 2021
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7XRJ
| crystal structure of N-acetyltransferase DgcN-25328 | Descriptor: | Putative NAD-dependent epimerase/dehydratase family protein, SULFATE ION | Authors: | Zhang, Y.Z, Yu, Y, Cao, H.Y, Chen, X.L, Wang, P. | Deposit date: | 2022-05-10 | Release date: | 2023-02-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Novel D-glutamate catabolic pathway in marine Proteobacteria and halophilic archaea. Isme J, 17, 2023
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7WG3
| Structural basis of interleukin-17B receptor in complex with a neutralizing antibody D9 for guiding humanization and affinity maturation for cancer therapy | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of D9 Fab, IL17RB protein, ... | Authors: | Lee, W.H, Chen, X.R, Liu, I.J, Lee, J.H, Hu, C.M, Wu, H.C, Wang, S.K, Lee, W.H, Ma, C. | Deposit date: | 2021-12-28 | Release date: | 2022-11-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation. Cell Rep, 41, 2022
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7YHN
| ANTI-TUMOR AGENT Y48 IN COMPLEX WITH TUBULIN | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-methyl-3-[(4-methylphenyl)sulfonylamino]-~{N}-[(6-methylpyridin-3-yl)methyl]benzamide, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Du, T, Ji, M, Hou, Z, Lin, S, Zhang, J, Wu, D, Zhang, K, Lu, D, Xu, H, Chen, X. | Deposit date: | 2022-07-14 | Release date: | 2023-07-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Optimization of Benzamide Derivatives as Potent and Orally Active Tubulin Inhibitors Targeting the Colchicine Binding Site. J.Med.Chem., 65, 2022
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7YJI
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7WLT
| the Curved Structure of mPIEZO1 in Lipid Bilayer | Descriptor: | (9R,11S)-9-({[(1S)-1-HYDROXYHEXADECYL]OXY}METHYL)-2,2-DIMETHYL-5,7,10-TRIOXA-2LAMBDA~5~-AZA-6LAMBDA~5~-PHOSPHAOCTACOSANE-6,6,11-TRIOL, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... | Authors: | Yang, X, Lin, C, Chen, X, Li, S, Li, X, Xiao, B. | Deposit date: | 2022-01-13 | Release date: | 2022-04-13 | Last modified: | 2022-07-06 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Structure deformation and curvature sensing of PIEZO1 in lipid membranes. Nature, 604, 2022
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7W6V
| Crystal structure of a dicobalt-substituted small laccase at 2.47 angstrom | Descriptor: | COBALT (II) ION, Putative copper oxidase | Authors: | Yang, X, Wu, F, Wu, W, Chen, X, Fan, S, Yu, P, Mao, L. | Deposit date: | 2021-12-02 | Release date: | 2022-11-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | A versatile artificial metalloenzyme scaffold enabling direct bioelectrocatalysis in solution. Sci Adv, 8, 2022
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7VKM
| Crystal structure of TrkA (G595R) kinase domain | Descriptor: | Tyrosine-protein kinase receptor | Authors: | Murray, B.W, Rogers, E, Zhai, D, Deng, W, Chen, X, Sprengeler, P.A, Zhang, X, Graber, A, Reich, S.H, Stopatschinskaja, S, Solomon, B, Besse, B, Drilon, A. | Deposit date: | 2021-09-30 | Release date: | 2021-10-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Molecular Characteristics of Repotrectinib That Enable Potent Inhibition of TRK Fusion Proteins and Resistant Mutations. Mol.Cancer Ther., 20, 2021
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