4TS1
 
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2TS1
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3TS1
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1CG2
 | | CARBOXYPEPTIDASE G2 | | Descriptor: | CARBOXYPEPTIDASE G2, ZINC ION | | Authors: | Rowsell, S, Pauptit, R.A, Tucker, A.D, Melton, R.G, Blow, D.M, Brick, P. | | Deposit date: | 1996-12-20 | | Release date: | 1997-12-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.
Structure, 5, 1997
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1COY
 | | CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES | | Descriptor: | 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Li, J, Vrielink, A, Brick, P, Blow, D.M. | | Deposit date: | 1993-06-14 | | Release date: | 1993-10-31 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.
Biochemistry, 32, 1993
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1BA3
 | | FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM | | Descriptor: | LUCIFERASE, TRIBROMOMETHANE | | Authors: | Franks, N.P, Jenkins, A, Conti, E, Lieb, W.R, Brick, P. | | Deposit date: | 1998-04-21 | | Release date: | 1998-11-11 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
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1TIE
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2C35
 | | Subunits Rpb4 and Rpb7 of human RNA polymerase II | | Descriptor: | DNA-DIRECTED RNA POLYMERASE II 16 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE II 19 KDA POLYPEPTIDE | | Authors: | Meka, H, Werner, F, Cordell, S.C, Onesti, S, Brick, P. | | Deposit date: | 2005-10-04 | | Release date: | 2005-11-18 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structure and RNA Binding of the Rpb4/Rpb7 Subunits of Human RNA Polymerase II.
Nucleic Acids Res., 33, 2005
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1BBU
 | | LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE | | Descriptor: | LYSINE, PROTEIN (LYSYL-TRNA SYNTHETASE) | | Authors: | Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P. | | Deposit date: | 1998-04-24 | | Release date: | 2000-11-10 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
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1BBW
 | | LYSYL-TRNA SYNTHETASE (LYSS) | | Descriptor: | PROTEIN (LYSYL-TRNA SYNTHETASE) | | Authors: | Onesti, S, Desogus, G, Brevet, A, Chen, J, Plateau, P, Blanquet, S, Brick, P. | | Deposit date: | 1998-04-24 | | Release date: | 2000-11-10 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
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1BA7
 | | SOYBEAN TRYPSIN INHIBITOR | | Descriptor: | TRYPSIN INHIBITOR (KUNITZ) | | Authors: | De Meester, P, Brick, P, Lloyd, L.F, Blow, D.M, Onesti, S. | | Deposit date: | 1998-04-22 | | Release date: | 1998-06-17 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator.
Acta Crystallogr.,Sect.D, 54, 1998
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2BHG
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1TYC
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1LYL
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3COX
 | | CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES | | Descriptor: | CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE | | Authors: | Vrielink, A, Li, J, Brick, P, Blow, D.M. | | Deposit date: | 1993-06-14 | | Release date: | 1993-10-31 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.
Biochemistry, 32, 1993
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1GDH
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1A0C
 | | XYLOSE ISOMERASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES | | Descriptor: | COBALT (II) ION, XYLOSE ISOMERASE | | Authors: | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | Deposit date: | 1997-11-28 | | Release date: | 1998-06-03 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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1A0D
 | | XYLOSE ISOMERASE FROM BACILLUS STEAROTHERMOPHILUS | | Descriptor: | MANGANESE (II) ION, XYLOSE ISOMERASE | | Authors: | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | Deposit date: | 1997-11-28 | | Release date: | 1998-06-03 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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1AMU
 | | PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE | | Descriptor: | ADENOSINE MONOPHOSPHATE, GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, ... | | Authors: | Conti, E, Stachelhaus, T, Marahiel, M.A, Brick, P. | | Deposit date: | 1997-06-18 | | Release date: | 1998-07-01 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
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1LCI
 | | FIREFLY LUCIFERASE | | Descriptor: | LUCIFERASE | | Authors: | Conti, E, Franks, N.P, Brick, P. | | Deposit date: | 1996-06-01 | | Release date: | 1997-03-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of firefly luciferase throws light on a superfamily of adenylate-forming enzymes.
Structure, 4, 1996
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1E1T
 | | LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH THE LYSYL_ADENYLATE INTERMEDIATE | | Descriptor: | ADENOSINE-5'-[LYSYL-PHOSPHATE], GLYCEROL, LYSYL-TRNA SYNTHETASE, ... | | Authors: | Desogus, G, Todone, F, Brick, P, Onesti, S. | | Deposit date: | 2000-05-10 | | Release date: | 2000-07-28 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
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1A0E
 | | XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA | | Descriptor: | COBALT (II) ION, XYLOSE ISOMERASE | | Authors: | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | Deposit date: | 1997-11-28 | | Release date: | 1998-06-03 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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1BCU
 | | ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN | | Descriptor: | ALPHA-THROMBIN, HIRUGEN, PROFLAVIN | | Authors: | Conti, E, Rivetti, C, Wonacott, A, Brick, P. | | Deposit date: | 1998-05-02 | | Release date: | 1998-10-14 | | Last modified: | 2023-08-02 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
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1FBL
 | | STRUCTURE OF FULL-LENGTH PORCINE SYNOVIAL COLLAGENASE (MMP1) REVEALS A C-TERMINAL DOMAIN CONTAINING A CALCIUM-LINKED, FOUR-BLADED BETA-PROPELLER | | Descriptor: | CALCIUM ION, FIBROBLAST (INTERSTITIAL) COLLAGENASE (MMP-1), N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE, ... | | Authors: | Li, J, Brick, P, Blow, D.M. | | Deposit date: | 1995-04-24 | | Release date: | 1996-01-29 | | Last modified: | 2012-02-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed beta-propeller.
Structure, 3, 1995
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1BJ5
 | | HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTIC ACID | | Descriptor: | HUMAN SERUM ALBUMIN, MYRISTIC ACID | | Authors: | Curry, S, Mandelkow, H, Brick, P, Franks, N. | | Deposit date: | 1998-07-02 | | Release date: | 1998-11-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites.
Nat.Struct.Biol., 5, 1998
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