1QP7
 
 | | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*CP*CP*GP*GP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | | Authors: | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | | Deposit date: | 1999-06-01 | | Release date: | 1999-06-04 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
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1QPZ
 | | PURINE REPRESSOR-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*AP*CP*GP*TP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | | Authors: | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | | Deposit date: | 1999-06-01 | | Release date: | 1999-06-07 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
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1QQA
 | | PURINE REPRESSOR MUTANT-HYPOXANTHINE-PALINDROMIC OPERATOR COMPLEX | | Descriptor: | DNA (5'-D(*TP*AP*CP*GP*CP*AP*AP*GP*CP*GP*CP*TP*TP*GP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE NUCLEOTIDE SYNTHESIS REPRESSOR) | | Authors: | Glasfeld, A, Koehler, A.N, Schumacher, M.A, Brennan, R.G. | | Deposit date: | 1999-06-01 | | Release date: | 1999-06-09 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | The role of lysine 55 in determining the specificity of the purine repressor for its operators through minor groove interactions.
J.Mol.Biol., 291, 1999
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1R8E
 | | Crystal Structure of BmrR Bound to DNA at 2.4A Resolution | | Descriptor: | 5'-D(*GP*AP*CP*CP*CP*TP*CP*CP*CP*CP*TP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*TP*C)-3', GLYCEROL, IMIDAZOLE, ... | | Authors: | Newberry, K.J, Brennan, R.G. | | Deposit date: | 2003-10-23 | | Release date: | 2004-08-17 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
J.Biol.Chem., 279, 2004
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1R8D
 | | Crystal Structure of MtaN Bound to DNA | | Descriptor: | 26-MER, SULFATE ION, transcription activator MtaN | | Authors: | Newberry, K.J, Brennan, R.G. | | Deposit date: | 2003-10-23 | | Release date: | 2004-08-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | The structural mechanism for transcription activation by MerR family member multidrug transporter activation, N terminus.
J.Biol.Chem., 279, 2004
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1BD3
 | | STRUCTURE OF THE APO URACIL PHOSPHORIBOSYLTRANSFERASE, 2 MUTANT C128V | | Descriptor: | PHOSPHATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE | | Authors: | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | | Deposit date: | 1998-05-12 | | Release date: | 1999-05-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
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1BD4
 | | UPRT-URACIL COMPLEX | | Descriptor: | PHOSPHATE ION, URACIL, URACIL PHOSPHORIBOSYLTRANSFERASE | | Authors: | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | | Deposit date: | 1998-05-12 | | Release date: | 1999-05-18 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding.
EMBO J., 17, 1998
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1BOW
 | | MULTIDRUG-BINDING DOMAIN OF TRANSCRIPTION ACTIVATOR BMRR (APO FORM) | | Descriptor: | MANGANESE (II) ION, MULTIDRUG-EFFLUX TRANSPORTER 1 REGULATOR BMRR | | Authors: | Zheleznova, E.E, Markham, P.N, Neyfakh, A.A, Brennan, R.G. | | Deposit date: | 1998-08-06 | | Release date: | 1999-08-06 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of multidrug recognition by BmrR, a transcription activator of a multidrug transporter.
Cell(Cambridge,Mass.), 96, 1999
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1DH3
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1DBR
 | | HYPOXANTHINE GUANINE XANTHINE | | Descriptor: | HYPOXANTHINE GUANINE XANTHINE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION | | Authors: | Schumacher, M.A, Carter, D, Roos, D, Ullman, B, Brennan, R.G. | | Deposit date: | 1996-02-13 | | Release date: | 1997-12-03 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structures of Toxoplasma gondii HGXPRTase reveal the catalytic role of a long flexible loop.
Nat.Struct.Biol., 3, 1996
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1DBQ
 | | DNA-BINDING REGULATORY PROTEIN | | Descriptor: | MAGNESIUM ION, PURINE REPRESSOR | | Authors: | Schumacher, M.A, Choi, K.Y, Lu, F, Zalkin, H, Brennan, R.G. | | Deposit date: | 1996-02-13 | | Release date: | 1996-12-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mechanism of corepressor-mediated specific DNA binding by the purine repressor.
Cell(Cambridge,Mass.), 83, 1995
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2DTZ
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2EV0
 | | Bacillus subtilis manganese transport regulator (MNTR) bound to cadmium | | Descriptor: | CADMIUM ION, Transcriptional regulator mntR | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-10-30 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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2EV5
 | | Bacillus subtilis manganese transport regulator (MNTR) bound to calcium | | Descriptor: | CALCIUM ION, Transcriptional regulator mntR | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-10-31 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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2F5E
 | | Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AB conformation, pH 6.5 | | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-11-25 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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3GIB
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2EV6
 | | Bacillus subtilis manganese transport regulator (MNTR) bound to zinc | | Descriptor: | CITRATE ANION, GLYCEROL, Transcriptional regulator mntR, ... | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-10-31 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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2F5F
 | | Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 8.5 | | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-11-25 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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2F5C
 | | Bacillus subtilis Manganese transport regulator (MNTR) bound to manganese, hexagonal crystal form | | Descriptor: | MANGANESE (II) ION, SULFATE ION, Transcriptional regulator mntR | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-11-25 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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2F5D
 | | Bacillus subtilis manganese transport regulator (MNTR) bound to manganese, AC conformation, pH 6.5 | | Descriptor: | MANGANESE (II) ION, Transcriptional regulator mntR | | Authors: | Kliegman, J.I, Griner, S.L, Helmann, J.D, Brennan, R.G, Glasfeld, A. | | Deposit date: | 2005-11-25 | | Release date: | 2006-03-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural Basis for the Metal-Selective Activation of the Manganese Transport Regulator of Bacillus subtilis.
Biochemistry, 45, 2006
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2H1C
 | | Crystal Structure of FitAcB from Neisseria gonorrhoeae | | Descriptor: | ACETATE ION, MAGNESIUM ION, SULFATE ION, ... | | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | | Deposit date: | 2006-05-16 | | Release date: | 2006-09-26 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
J.Biol.Chem., 281, 2006
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2H1O
 | | Structure of FitAB bound to IR36 DNA fragment | | Descriptor: | IR36-strand 1, IR36-strand 2, Trafficking protein A, ... | | Authors: | Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. | | Deposit date: | 2006-05-16 | | Release date: | 2006-09-26 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs.
J.Biol.Chem., 281, 2006
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2HQ5
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3IAO
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1KQ1
 | | 1.55 A Crystal structure of the pleiotropic translational regulator, Hfq | | Descriptor: | ACETIC ACID, Host Factor for Q beta | | Authors: | Schumacher, M.A, Pearson, R.F, Moller, T, Valentin-Hansen, P, Brennan, R.G. | | Deposit date: | 2002-01-03 | | Release date: | 2002-07-10 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structures of the pleiotropic translational regulator Hfq and an Hfq-RNA complex: a bacterial Sm-like protein.
EMBO J., 21, 2002
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