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PDB: 1 results

8CGC
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BU of 8cgc by Molmil
Structure of CSF1R in complex with a pyrollopyrimidine (compound 23)
Descriptor: (2S)-2-hydroxybutanedioic acid, GLYCEROL, Macrophage colony-stimulating factor 1 receptor, ...
Authors:Aarhus, T.I, Bjornstad, F, Wolowczyk, C, Larsen, K.U, Rognstad, L, Leithaug, T, Unger, A, Habenberger, P, Wolff, A, Bjorkoy, G, Pridans, C, Eickhoff, J, Klebl, B, Hoff, B.H, Sundby, E.
Deposit date:2023-02-03
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.925 Å)
Cite:Synthesis and Development of Highly Selective Pyrrolo[2,3- d ]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form.
J.Med.Chem., 66, 2023

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