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PDB: 71 results

7UDN
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BU of 7udn by Molmil
Crystal structure of designed helical repeat protein RPB_PLP1_R6 in alternative conformation 2
Descriptor: Designed helical repeat protein (DHR) RPB_PLP1_R6
Authors:Chang, Y, Redler, R.L, Bhabha, G, Ekiert, D.C.
Deposit date:2022-03-20
Release date:2023-03-22
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
7UPO
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BU of 7upo by Molmil
Crystal structure of designed heterotrimeric assembly DHT03
Descriptor: DHT03 protein A, DHT03 protein B, DHT03 protein C
Authors:Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2022-04-16
Release date:2022-12-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:De novo design of obligate ABC-type heterotrimeric proteins.
Nat.Struct.Mol.Biol., 29, 2022
7UPP
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BU of 7upp by Molmil
Crystal structure of designed heterotrimeric assembly DHT03_2arm_A21/B21/C long
Descriptor: DHT03 protein A, DHT03 protein B, DHT03 protein C
Authors:Chang, Y, Bhabha, G, Ekiert, D.C.
Deposit date:2022-04-16
Release date:2022-12-14
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.35 Å)
Cite:De novo design of obligate ABC-type heterotrimeric proteins.
Nat.Struct.Mol.Biol., 29, 2022
7UE2
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BU of 7ue2 by Molmil
Crystal structure of designed helical repeat protein RPB_PLP3_R6 bound to PLPx6 peptide
Descriptor: PLPx6 peptide, RPB_PLP3_R6
Authors:Chang, Y, Ekiert, D.C, Bhabha, G.
Deposit date:2022-03-21
Release date:2023-03-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:De novo design of modular peptide-binding proteins by superhelical matching.
Nature, 616, 2023
6V0F
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BU of 6v0f by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 4
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (2.96 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6V0H
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BU of 6v0h by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 6
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6V0C
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BU of 6v0c by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 1
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6V0E
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BU of 6v0e by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 3
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6V0J
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BU of 6v0j by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 8
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.78 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6V0G
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BU of 6v0g by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 5
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6V0I
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BU of 6v0i by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 7
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6VCI
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BU of 6vci by Molmil
Lipophilic envelope-spanning tunnel protein (LetB), domains MCE2-MCE3
Descriptor: Lipophilic envelope-spanning tunnel protein LetB
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-12-21
Release date:2020-05-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
6V0D
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BU of 6v0d by Molmil
Lipophilic Envelope-spanning Tunnel B (LetB), Model 2
Descriptor: Intermembrane transport protein YebT
Authors:Isom, G.L, Coudray, N, MacRae, M.R, McManus, C.T, Ekiert, D.C, Bhabha, G.
Deposit date:2019-11-18
Release date:2020-05-06
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.49 Å)
Cite:LetB Structure Reveals a Tunnel for Lipid Transport across the Bacterial Envelope.
Cell, 181, 2020
7MI8
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BU of 7mi8 by Molmil
Signal subtracted reconstruction of AAA5 and AAA6 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 5
Descriptor: Fusion protein of Dynein and Endolysin
Authors:Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI6
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BU of 7mi6 by Molmil
Yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound, Model 1
Descriptor: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
Authors:Santarossa, C.C, Urnavicius, L, Coudray, N, Ekeirt, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI3
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BU of 7mi3 by Molmil
Signal subtracted reconstruction of AAA2, AAA3, and AAA4 domains of dynein in the presence of a pyrazolo-pyrimidinone-based compound, Model 4
Descriptor: (8S)-6-(3-bromophenoxy)-2-[1-(4-chlorophenyl)cyclopropyl]-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile, ADENOSINE-5'-TRIPHOSPHATE, Fusion protein of Dynein and Endolysin, ...
Authors:Santarossa, C.C, Coudray, N, Urnavicius, L, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2021-11-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
7MI1
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BU of 7mi1 by Molmil
X-ray structure of yeast dynein motor domain in the presence of a pyrazolo-pyrimidinone-based compound (compound 20)
Descriptor: Chimera protein of Dynein and Endolysin
Authors:Santarossa, C.C, Ekiert, D.C, Bhabha, G, Kapoor, T.M.
Deposit date:2021-04-16
Release date:2021-05-26
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (4.5 Å)
Cite:Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Cell Chem Biol, 28, 2021
6XSS
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BU of 6xss by Molmil
CryoEM structure of designed helical fusion protein C4_nat_HFuse-7900
Descriptor: C4_nat_HFuse-7900
Authors:Redler, R.L, Edman, N.I, Baker, D, Ekiert, D, Bhabha, G.
Deposit date:2020-07-16
Release date:2020-12-23
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Design of multi-scale protein complexes by hierarchical building block fusion.
Nat Commun, 12, 2021
4KJL
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BU of 4kjl by Molmil
Room Temperature N23PPS148A DHFR
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:Automated identification of functional dynamic contact networks from X-ray crystallography.
Nat.Methods, 10, 2013
4KJJ
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BU of 4kjj by Molmil
Cryogenic WT DHFR
Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Automated identification of functional dynamic contact networks from X-ray crystallography.
Nat.Methods, 10, 2013
4KJK
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BU of 4kjk by Molmil
Room Temperature WT DHFR
Descriptor: CALCIUM ION, Dihydrofolate reductase, FOLIC ACID, ...
Authors:van den Bedem, H, Bhabha, G, Yang, K, Wright, P.E, Fraser, J.S.
Deposit date:2013-05-03
Release date:2013-08-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.351 Å)
Cite:Automated identification of functional dynamic contact networks from X-ray crystallography.
Nat.Methods, 10, 2013
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