6EI1
| Crystal structure of the covalent complex between deubiquitinase ZUFSP (ZUP1) and Ubiquitin-PA | Descriptor: | GLYCEROL, MALONATE ION, Polyubiquitin-B, ... | Authors: | Pichlo, C, Baumann, U, Hofmann, K, Hermanns, T. | Deposit date: | 2017-09-16 | Release date: | 2018-03-07 | Last modified: | 2019-10-16 | Method: | X-RAY DIFFRACTION (1.732 Å) | Cite: | A family of unconventional deubiquitinases with modular chain specificity determinants. Nat Commun, 9, 2018
|
|
6FSM
| Crystal structure of TCE-treated Thermolysin | Descriptor: | CALCIUM ION, GLYCEROL, LYSINE, ... | Authors: | Pichlo, C, Baumann, U. | Deposit date: | 2018-02-19 | Release date: | 2018-05-02 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Improved protein-crystal identification by using 2,2,2-trichloroethanol as a fluorescence enhancer. Acta Crystallogr F Struct Biol Commun, 74, 2018
|
|
6GCO
| Truncated FtsH from A. aeolicus in P312 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ATP-dependent zinc metalloprotease FtsH, ZINC ION | Authors: | Uthoff, M, Baumann, U. | Deposit date: | 2018-04-18 | Release date: | 2018-08-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.323 Å) | Cite: | Conformational flexibility of pore loop-1 gives insights into substrate translocation by the AAA+protease FtsH. J. Struct. Biol., 204, 2018
|
|
8OXL
| |
8OXI
| |
8OXK
| |
8PHY
| |
8OXH
| |
8OXJ
| |
8PZ3
| |
8Q00
| TssM-Ub-PA complex - A USP-like DUB from B. pseudomallei (193-430) reacted with Ub-PA | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, Polyubiquitin-B, ... | Authors: | Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2023-07-27 | Release date: | 2023-12-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | The structural basis for deubiquitination by the fingerless USP-type effector TssM. Life Sci Alliance, 7, 2024
|
|
3LUM
| Structure of ulilysin mutant M290L | Descriptor: | ARGININE, CALCIUM ION, GLYCEROL, ... | Authors: | Tallant, C, Garcia-Castellanos, R, Baumann, U, Gomis-Ruth, F.X. | Deposit date: | 2010-02-18 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | On the relevance of the Met-turn methionine in metzincins. J.Biol.Chem., 285, 2010
|
|
3LUN
| Structure of ulilysin mutant M290C | Descriptor: | ARGININE, CALCIUM ION, GLYCEROL, ... | Authors: | Tallant, C, Garcia-Castellanos, R, Baumann, U, Gomis-Ruth, F.X. | Deposit date: | 2010-02-18 | Release date: | 2010-03-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | On the relevance of the Met-turn methionine in metzincins. J.Biol.Chem., 285, 2010
|
|
8ADC
| Viral tegument-like DUBs | Descriptor: | Viral deubiquitinating enzyme | Authors: | Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K. | Deposit date: | 2022-07-08 | Release date: | 2023-02-15 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
|
|
8ADB
| Viral tegument-like DUBs | Descriptor: | CITRIC ACID, Polyubiquitin-C, Wc-VDT1, ... | Authors: | Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K. | Deposit date: | 2022-07-08 | Release date: | 2023-02-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.73 Å) | Cite: | A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins. Nat Commun, 13, 2022
|
|
8CMR
| Linear specific OTU-type DUB SnOTU from the pathogen S. negenvensis in complex with linear di-ubiquitin | Descriptor: | OTU domain-containing protein, Polyubiquitin-B | Authors: | Uthoff, M, Hermanns, T, Boll, V, Hofmann, K, Baumann, U. | Deposit date: | 2023-02-21 | Release date: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis. Nat Commun, 14, 2023
|
|
3CT4
| Structure of Dha-kinase subunit DhaK from L. Lactis | Descriptor: | Dihydroxyacetone, PTS-dependent dihydroxyacetone kinase, dihydroxyacetone-binding subunit dhaK | Authors: | Jeckelmann, J.M, Zurbriggen, A, Christen, S, Baumann, U, Erni, B. | Deposit date: | 2008-04-11 | Release date: | 2008-10-21 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | X-ray Structures of the Three Lactococcus lactis Dihydroxyacetone Kinase Subunits and of a Transient Intersubunit Complex. J.Biol.Chem., 283, 2008
|
|
6ZMK
| Crystal structure of human GFAT-1 L405R | Descriptor: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | Authors: | Ruegenberg, S, Mayr, F, Miethe, S, Atanassov, I, Baumann, U, Denzel, M.S. | Deposit date: | 2020-07-02 | Release date: | 2020-08-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.382 Å) | Cite: | Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun, 12, 2021
|
|
6ZMJ
| Crystal structure of human GFAT-1 R203H | Descriptor: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | Authors: | Ruegenberg, S, Mayr, F, Miethe, S, Atanassov, I, Baumann, U, Denzel, M.S. | Deposit date: | 2020-07-02 | Release date: | 2020-08-05 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.774 Å) | Cite: | Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun, 12, 2021
|
|
3CR3
| Structure of a transient complex between Dha-kinase subunits DhaM and DhaL from Lactococcus lactis | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PTS-dependent dihydroxyacetone kinase, ... | Authors: | Jeckelmann, J.M, Zurbriggen, A, Christen, S, Baumann, U, Erni, B. | Deposit date: | 2008-04-04 | Release date: | 2008-10-21 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | X-ray Structures of the Three Lactococcus lactis Dihydroxyacetone Kinase Subunits and of a Transient Intersubunit Complex. J.Biol.Chem., 283, 2008
|
|
5FR2
| Farnesylated RhoA-GDP in complex with RhoGDI-alpha, lysine acetylated at K178 | Descriptor: | FARNESYL, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kuhlmann, N, Wroblowski, S, Knyphausen, P, de Boor, S, Brenig, J, Zienert, A.Y, Meyer-Teschendorf, K, Praefcke, G.J.K, Nolte, H, Krueger, M, Schacherl, M, Baumann, U, James, L.C, Chin, J.W, Lammers, M. | Deposit date: | 2015-12-15 | Release date: | 2016-01-13 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural and Mechanistic Insights Into the Regulation of the Fundamental Rho-Regulator Rhogdi Alpha by Lysine Acetylation. J.Biol.Chem., 291, 2016
|
|
6HMP
| Crystal structure of human Casein Kinase I delta in complex with a photoswitchable 2-Azoimidazole-based Inhibitor (compound 3) | Descriptor: | 3-(2,5-dimethoxyphenyl)-~{N}-[4-[5-(4-fluorophenyl)-2-[(~{E})-(4-fluorophenyl)diazenyl]-3-methyl-imidazol-4-yl]pyridin-2-yl]propanamide, Casein kinase I isoform delta, PHOSPHATE ION | Authors: | Pichlo, C, Schehr, M, Charl, J, Brunstein, E, Peifer, C, Baumann, U. | Deposit date: | 2018-09-12 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.039 Å) | Cite: | 2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach. Photochem. Photobiol. Sci., 18, 2019
|
|
5FYQ
| Sirt2 in complex with a 13-mer trifluoroacetylated Ran peptide | Descriptor: | NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2, RAN AA 31-43, SULFATE ION, ... | Authors: | Knyphausen, P, de Boor, S, Scislowski, L, Extra, A, Baldus, L, Schacherl, M, Baumann, U, Neundorf, I, Lammers, M. | Deposit date: | 2016-03-09 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Insights Into Lysine-Deacetylation of Natively Folded Substrate Proteins by Sirtuins. J.Biol.Chem., 291, 2016
|
|
5G5R
| |
6HMR
| Crystal structure of human Casein Kinase I delta in complex with a photoswitchable 2-Azothiazole-based inhibitor (compound 2) | Descriptor: | 3-(2,5-dimethoxyphenyl)-~{N}-[4-[4-(4-fluorophenyl)-2-[(~{E})-phenyldiazenyl]-1,3-thiazol-5-yl]pyridin-2-yl]propanamide, Casein kinase I isoform delta, MALONIC ACID | Authors: | Pichlo, C, Schehr, M, Charl, J, Brunstein, E, Peifer, C, Baumann, U. | Deposit date: | 2018-09-12 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.782 Å) | Cite: | 2-Azo-, 2-diazocine-thiazols and 2-azo-imidazoles as photoswitchable kinase inhibitors: limitations and pitfalls of the photoswitchable inhibitor approach. Photochem. Photobiol. Sci., 18, 2019
|
|