1LFH
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![BU of 1lfh by Molmil](/molmil-images/mine/1lfh) | MOLECULAR REPLACEMENT SOLUTION OF THE STRUCTURE OF APOLACTOFERRIN, A PROTEIN DISPLAYING LARGE-SCALE CONFORMATIONAL CHANGE | Descriptor: | CHLORIDE ION, LACTOFERRIN | Authors: | Anderson, B.F, Baker, E.N, Norris, G.E. | Deposit date: | 1991-09-04 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular replacement solution of the structure of apolactoferrin, a protein displaying large-scale conformational change. Acta Crystallogr.,Sect.B, 47, 1991
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1IX9
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![BU of 1ix9 by Molmil](/molmil-images/mine/1ix9) | Crystal Structure of the E. coli Manganase(III) superoxide dismutase mutant Y174F at 0.90 angstroms resolution. | Descriptor: | MANGANESE (II) ION, Superoxide Dismutase | Authors: | Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B. | Deposit date: | 2002-06-17 | Release date: | 2002-12-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli To be Published
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1IXB
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![BU of 1ixb by Molmil](/molmil-images/mine/1ixb) | CRYSTAL STRUCTURE OF THE E. COLI MANGANESE(II) SUPEROXIDE DISMUTASE MUTANT Y174F AT 0.90 ANGSTROMS RESOLUTION. | Descriptor: | MANGANESE ION, 1 HYDROXYL COORDINATED, SUPEROXIDE DISMUTASE | Authors: | Anderson, B.F, Edwards, R.A, Whittaker, M.M, Whittaker, J.W, Baker, E.N, Jameson, G.B. | Deposit date: | 2002-06-18 | Release date: | 2002-12-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (0.9 Å) | Cite: | Structures at 0.90 A resolution of the oxidised and reduced forms of the Y174F mutant of the manganese superoxide dismutase from Escherichia coli To be Published
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4IUW
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![BU of 4iuw by Molmil](/molmil-images/mine/4iuw) | Crystal structure of PEPO from Lactobacillus rhamnosis HN001 (DR20) | Descriptor: | CARBONATE ION, CITRIC ACID, Neutral endopeptidase, ... | Authors: | Anderson, B.F, Knapp, K.M, Holland, R, Norris, G.E, Christensson, C, Bratt, H, Collins, L.J, Coolbear, T, Lubbers, M.W, Toole, P.W.O, Reid, J.R, Jameson, G.B. | Deposit date: | 2013-01-21 | Release date: | 2013-03-20 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of PEPO from Lactobacillus rhamnosis HN001 (DR20) TO BE PUBLISHED
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6D9S
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![BU of 6d9s by Molmil](/molmil-images/mine/6d9s) | The (p)ppGpp-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | Descriptor: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5',3'-TETRAPHOSPHATE, Hypoxanthine phosphoribosyltransferase, ... | Authors: | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | Deposit date: | 2018-04-30 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.105 Å) | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife, 8, 2019
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6YCS
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![BU of 6ycs by Molmil](/molmil-images/mine/6ycs) | Human Transcription Cofactor PC4 DNA-binding domain in complex with full phosphorothioate 5-10-5 2'-O-methyl DNA gapmer antisense oligonucleotide. | Descriptor: | DNA (5'-D(P*(OKQ))-D(P*(OKT))-R(P*(RFJ))-D(*(OKQ)P*(OKT)P*(AS)P*(GS)P*(OKN)P*(OKN)P*(PST)P*(OKN)P*(PST)P*(GS)P*(GS)P*(AS)P*(OKT)P*(OKT))-3'), PC4 protein, SODIUM ION, ... | Authors: | Hyjek-Skladanowska, M, Vickers, T.A, Napiorkowska, A, Anderson, B, Tanowitz, M, Crooke, S.T, Liang, X, Seth, P.P, Nowotny, M. | Deposit date: | 2020-03-19 | Release date: | 2020-04-29 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Origins of the Increased Affinity of Phosphorothioate-Modified Therapeutic Nucleic Acids for Proteins. J.Am.Chem.Soc., 142, 2020
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4N5H
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![BU of 4n5h by Molmil](/molmil-images/mine/4n5h) | Crystal structure of ESTERASE B from Lactobacillus Rhamnosis (HN001) | Descriptor: | CALCIUM ION, CHLORIDE ION, Esterase/lipase, ... | Authors: | Bennett, M.D, Holland, R, Loo, T.S, Smith, C.A, Norris, G.E, Delabre, M.-L, Anderson, B.F. | Deposit date: | 2013-10-09 | Release date: | 2014-10-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Crystal structure of ESTERASE B from Lactobacillus Rhamnosis (HN001) TO BE PUBLISHED
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7ZVX
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![BU of 7zvx by Molmil](/molmil-images/mine/7zvx) | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 2.4 A resolution | Descriptor: | 1,2-ETHANEDIOL, 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, ... | Authors: | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | Deposit date: | 2022-05-17 | Release date: | 2022-09-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding. Nucleic Acids Res., 51, 2023
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7ZVN
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![BU of 7zvn by Molmil](/molmil-images/mine/7zvn) | Crystal structure of human Annexin A2 in complex with full phosphorothioate 5-10 2'-methoxyethyl DNA gapmer antisense oligonucleotide solved at 1.87 A resolution | Descriptor: | 2'-methoxyethyl DNA gapmer antisense oligonucleotide, Annexin A2, CALCIUM ION, ... | Authors: | Hyjek-Skladanowska, M, Anderson, B, Mykhaylyk, V, Orr, C, Wagner, A, Skowronek, K, Seth, P, Nowotny, M. | Deposit date: | 2022-05-16 | Release date: | 2022-09-14 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Structures of annexin A2-PS DNA complexes show dominance of hydrophobic interactions in phosphorothioate binding. Nucleic Acids Res., 51, 2023
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1H43
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![BU of 1h43 by Molmil](/molmil-images/mine/1h43) | R210E N-TERMINAL LOBE HUMAN LACTOFERRIN | Descriptor: | CARBONATE ION, FE (III) ION, LACTOFERRIN | Authors: | Peterson, N.A, Arcus, V.L, Anderson, B.F, Jameson, G.B, Tweedie, J.W, Baker, E.N. | Deposit date: | 2002-10-02 | Release date: | 2002-11-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | "Dilysine Trigger" in Transferrins Probed by Mutagenesis of Lactoferrin: Crystal Structures of the R210G, R210E, and R210L Mutants of Human Lactoferrin Biochemistry, 41, 2002
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1H45
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![BU of 1h45 by Molmil](/molmil-images/mine/1h45) | R210G N-TERMINAL LOBE HUMAN LACTOFERRIN | Descriptor: | CARBONATE ION, FE (III) ION, LACTOFERRIN | Authors: | Peterson, N.A, Anderson, B.F, Jameson, G.B, Tweedie, J.W, Baker, E.N. | Deposit date: | 2002-10-03 | Release date: | 2002-11-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | "Dilysine Trigger" in Transferrins Probed by Mutagenesis of Lactoferrin: Crystal Structures of the R210G, R210E, and R210L Mutants of Human Lactoferrin Biochemistry, 41, 2002
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1H44
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![BU of 1h44 by Molmil](/molmil-images/mine/1h44) | R210L N-TERMINAL LOBE HUMAN LACTOFERRIN | Descriptor: | CARBONATE ION, FE (III) ION, LACTOFERRIN | Authors: | Peterson, N.A, Arcus, V.L, Anderson, B.F, Jameson, G.B, Tweedie, J.W, Baker, E.N. | Deposit date: | 2002-10-03 | Release date: | 2002-11-28 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | "Dilysine Trigger" in Transferrins Probed by Mutagenesis of Lactoferrin: Crystal Structures of the R210G, R210E, and R210L Mutants of Human Lactoferrin Biochemistry, 41, 2002
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6W1I
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![BU of 6w1i by Molmil](/molmil-images/mine/6w1i) | Re-interpretation of ppGpp (G4P) electron density in the deposited crystal structure of Xanthine phosphoribosyltransferase (XPRT) (1Y0B). | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, SODIUM ION, Xanthine phosphoribosyltransferase | Authors: | Satyshur, K.A, Anderson, B.W, Keck, J.L, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2020-03-04 | Release date: | 2020-07-29 | Last modified: | 2021-04-07 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular Mechanism of Regulation of the Purine Salvage Enzyme XPRT by the Alarmones pppGpp, ppGpp, and pGpp. J.Mol.Biol., 432, 2020
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2AKQ
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![BU of 2akq by Molmil](/molmil-images/mine/2akq) | The structure of bovine B-lactoglobulin A in crystals grown at very low ionic strength | Descriptor: | Beta-lactoglobulin variant A | Authors: | Adams, J.J, Anderson, B.F, Norris, G.E, Creamer, L.K, Jameson, G.B. | Deposit date: | 2005-08-03 | Release date: | 2005-08-16 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of bovine beta-lactoglobulin (variant A) at very low ionic strength J.Struct.Biol., 154, 2006
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6D9Q
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![BU of 6d9q by Molmil](/molmil-images/mine/6d9q) | The sulfate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | Descriptor: | GLYCEROL, Hypoxanthine phosphoribosyltransferase, SULFATE ION | Authors: | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | Deposit date: | 2018-04-30 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.056 Å) | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife, 8, 2019
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1CB6
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![BU of 1cb6 by Molmil](/molmil-images/mine/1cb6) | STRUCTURE OF HUMAN APOLACTOFERRIN AT 2.0 A RESOLUTION. | Descriptor: | CHLORIDE ION, Lactotransferrin | Authors: | Jameson, G.B, Anderson, B.F, Norris, G.E, Thomas, D.H, Baker, E.N. | Deposit date: | 1999-03-01 | Release date: | 1999-03-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of human apolactoferrin at 2.0 A resolution. Refinement and analysis of ligand-induced conformational change. Acta Crystallogr.,Sect.D, 54, 1998
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1ZCO
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![BU of 1zco by Molmil](/molmil-images/mine/1zco) | Crystal structure of pyrococcus furiosus 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase | Descriptor: | 2-dehydro-3-deoxyphosphoheptonate aldolase, CHLORIDE ION, MANGANESE (II) ION, ... | Authors: | Schofield, L.R, Anderson, B.F, Patchett, M.L, Norris, G.E, Jameson, G.B, Parker, E.J. | Deposit date: | 2005-04-12 | Release date: | 2005-10-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Substrate Ambiguity and Crystal Structure of Pyrococcus furiosus 3-Deoxy-d-arabino-heptulosonate-7-phosphate Synthase: An Ancestral 3-Deoxyald-2-ulosonate-phosphate Synthase?(,) Biochemistry, 44, 2005
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1LFG
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![BU of 1lfg by Molmil](/molmil-images/mine/1lfg) | Structure of diferric human lactoferrin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | Authors: | Baker, E.N, Anderson, B.F, Haridas, M. | Deposit date: | 1992-02-05 | Release date: | 1994-01-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of human diferric lactoferrin refined at 2.2 A resolution. Acta Crystallogr.,Sect.D, 51, 1995
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6D9R
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![BU of 6d9r by Molmil](/molmil-images/mine/6d9r) | The substrate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | Descriptor: | 1,2-ETHANEDIOL, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 9-DEAZAGUANINE, ... | Authors: | Satyshur, K.A, Wolak, C, Anderson, B, Dubiel, K, Keck, J.L. | Deposit date: | 2018-04-30 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction. Elife, 8, 2019
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1LFI
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![BU of 1lfi by Molmil](/molmil-images/mine/1lfi) | METAL SUBSTITUTION IN TRANSFERRINS: THE CRYSTAL STRUCTURE OF HUMAN COPPER-LACTOFERRIN AT 2.1 ANGSTROMS RESOLUTION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, COPPER (II) ION, ... | Authors: | Smith, C.A, Anderson, B.F, Baker, H.M, Baker, E.N. | Deposit date: | 1992-02-10 | Release date: | 1993-10-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Metal substitution in transferrins: the crystal structure of human copper-lactoferrin at 2.1-A resolution. Biochemistry, 31, 1992
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2A0I
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![BU of 2a0i by Molmil](/molmil-images/mine/2a0i) | F Factor TraI Relaxase Domain bound to F oriT Single-stranded DNA | Descriptor: | F plasmid single-stranded oriT DNA, IMIDAZOLE, MAGNESIUM ION, ... | Authors: | Larkin, C, Datta, S, Harley, M.J, Anderson, B.J, Ebie, A, Hargreaves, V, Schildbach, J.F. | Deposit date: | 2005-06-16 | Release date: | 2005-10-25 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Inter- and intramolecular determinants of the specificity of single-stranded DNA binding and cleavage by the f factor relaxase. Structure, 13, 2005
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1PGS
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![BU of 1pgs by Molmil](/molmil-images/mine/1pgs) | THE THREE-DIMENSIONAL STRUCTURE OF PNGASE F, A GLYCOSYLASPARAGINASE FROM FLAVOBACTERIUM MENINGOSEPTICUM | Descriptor: | PEPTIDE-N(4)-(N-ACETYL-BETA-D-GLUCOSAMINYL)ASPARAGINE AMIDASE F | Authors: | Norris, G.E, Stillman, T.J, Anderson, B.F, Baker, E.N. | Deposit date: | 1994-10-06 | Release date: | 1995-01-26 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The three-dimensional structure of PNGase F, a glycosylasparaginase from Flavobacterium meningosepticum. Structure, 2, 1994
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1AIZ
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![BU of 1aiz by Molmil](/molmil-images/mine/1aiz) | STRUCTURE OF APO-AZURIN FROM ALCALIGENES DENITRIFICANS AT 1.8 ANGSTROMS RESOLUTION | Descriptor: | AZURIN, CADMIUM ION, SULFATE ION | Authors: | Baker, E.N, Anderson, B.F, Blackwell, K.A. | Deposit date: | 1993-11-11 | Release date: | 1994-01-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of apo-azurin from Alcaligenes denitrificans at 1.8 A resolution. Acta Crystallogr.,Sect.D, 49, 1993
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1LCF
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![BU of 1lcf by Molmil](/molmil-images/mine/1lcf) | CRYSTAL STRUCTURE OF COPPER-AND OXALATE-SUBSTITUTED HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, COPPER (II) ION, ... | Authors: | Smith, C.A, Anderson, B.F, Baker, H.M, Baker, E.N. | Deposit date: | 1994-01-11 | Release date: | 1994-08-31 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of copper- and oxalate-substituted human lactoferrin at 2.0 A resolution. Acta Crystallogr.,Sect.D, 50, 1994
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4G41
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![BU of 4g41 by Molmil](/molmil-images/mine/4g41) | Crystal structure of s-adenosylhomocysteine nucleosidase from streptococcus pyogenes in complex with 5-methylthiotubericidin | Descriptor: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, MTA/SAH nucleosidase | Authors: | Ponniah, K, Norris, G.E, Anderson, B.F, Brown, R.L, Tyler, P.C, Evans, G.B, Frohlich, R. | Deposit date: | 2012-07-15 | Release date: | 2012-09-12 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of s-adenosylhomocysteine nucleosidase from streptococcus pyogenes in complex with 5-methylthiotubericidin; TO BE PUBLISHED
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