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PDB: 131 results

1P7D
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Crystal structure of the Lambda Integrase (residues 75-356) bound to DNA
Descriptor: 26-MER, 5'-D(*CP*AP*AP*TP*GP*CP*CP*AP*AP*CP*TP*TP*T)-3', Integrase
Authors:Aihara, H, Kwon, H.J, Nunes-Duby, S.E, Landy, A, Ellenberger, T.
Deposit date:2003-05-01
Release date:2003-08-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:A Conformational Switch Controls the DNA Cleavage Activity of Lambda Integrase
Mol.Cell, 12, 2003
2V6E
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protelomerase TelK complexed with substrate DNA
Descriptor: PROTELEMORASE, TELRL, VANADATE ION
Authors:Aihara, H, Huang, W.M, Ellenberger, T.
Deposit date:2007-07-17
Release date:2007-10-02
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:An Interlocked Dimer of the Protelomerase Telk Distorts DNA Structure for the Formation of Hairpin Telomeres
Mol.Cell, 27, 2007
1B22
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RAD51 (N-TERMINAL DOMAIN)
Descriptor: DNA REPAIR PROTEIN RAD51
Authors:Aihara, H, Ito, Y, Kurumizaka, H, Yokoyama, S, Shibata, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1998-12-04
Release date:1999-12-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR.
J.Mol.Biol., 290, 1999
1AA3
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C-TERMINAL DOMAIN OF THE E. COLI RECA, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor: RECA
Authors:Aihara, H, Ito, Y, Kurumizaka, H, Terada, T, Yokoyama, S, Shibata, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:1997-01-22
Release date:1997-07-23
Last modified:2024-04-10
Method:SOLUTION NMR
Cite:An interaction between a specified surface of the C-terminal domain of RecA protein and double-stranded DNA for homologous pairing.
J.Mol.Biol., 274, 1997
6DFY
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BU of 6dfy by Molmil
Remodeled crystal structure of DNA-bound DUX4-HD2
Descriptor: DNA (5'-D(*AP*AP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*CP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*A)-3'), Double homeobox protein 4
Authors:Aihara, H, Shi, K.
Deposit date:2018-05-15
Release date:2018-09-05
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.623 Å)
Cite:Comment on structural basis of DUX4/IGH-driven transactivation.
Leukemia, 32, 2018
6XC1
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Crystal structure of bacteriophage T4 spackle and lysozyme in orthorhombic form
Descriptor: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Lysozyme, ...
Authors:Shi, K, Oakland, J.T, Kurniawan, F, Moeller, N.H, Aihara, H.
Deposit date:2020-06-07
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis of superinfection exclusion by bacteriophage T4 Spackle.
Commun Biol, 3, 2020
7SPP
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BU of 7spp by Molmil
Crystal structure of the SARS-CoV-2 receptor binding domain in complex with VNAR 2C02
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Shi, K, Aihara, H.
Deposit date:2021-11-02
Release date:2022-01-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography.
Nat Commun, 12, 2021
7SPO
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Crystal structure of the SARS-CoV-2 receptor binding domain in complex with VNAR 3B4
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
Authors:Shi, K, Aihara, H.
Deposit date:2021-11-02
Release date:2022-01-05
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography.
Nat Commun, 12, 2021
8VQR
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Crystal structure of chimeric SARS-CoV-2 RBD complexed with chimeric raccoon dog ACE2
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Hsueh, F.-C, Shi, K, Aihara, H, Li, F.
Deposit date:2024-01-19
Release date:2024-05-01
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.565 Å)
Cite:Structural basis for raccoon dog receptor recognition by SARS-CoV-2
To Be Published
6DT1
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Crystal structure of the ligase from bacteriophage T4 complexed with DNA intermediate
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, ADENOSINE MONOPHOSPHATE, CHLORIDE ION, ...
Authors:Shi, K, Aihara, H.
Deposit date:2018-06-14
Release date:2018-09-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction.
Nucleic Acids Res., 46, 2018
6DHJ
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BU of 6dhj by Molmil
Crystal structures of cyanuric acid hydrolase from Moorella thermoacetica
Descriptor: CITRIC ACID, Cyanuric acid amidohydrolase
Authors:Shi, K, Aihara, H.
Deposit date:2018-05-20
Release date:2019-06-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of Moorella thermoacetica cyanuric acid hydrolase reveal conformational flexibility and asymmetry important for catalysis.
Plos One, 14, 2019
4F43
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Protelomerase TelA mutant R255A complexed with CAAG hairpin DNA
Descriptor: DNA hairpin, Protelomerase
Authors:Shi, K, Aihara, H.
Deposit date:2012-05-10
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.354 Å)
Cite:Linear Chromosome-generating System of Agrobacterium tumefaciens C58: PROTELOMERASE GENERATES AND PROTECTS HAIRPIN ENDS.
J.Biol.Chem., 287, 2012
4F41
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Protelomerase TelA mutant R255A complexed with CTTG hairpin DNA
Descriptor: DNA hairpin, Protelomerase
Authors:Shi, K, Aihara, H.
Deposit date:2012-05-09
Release date:2012-06-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Linear Chromosome-generating System of Agrobacterium tumefaciens C58: PROTELOMERASE GENERATES AND PROTECTS HAIRPIN ENDS.
J.Biol.Chem., 287, 2012
4F1I
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Crystal structure of SeMet TDP2 from Caenorhabditis elegans
Descriptor: 5'-tyrosyl-DNA phosphodiesterase, GLYCEROL
Authors:Shi, K, Kurahashi, K, Aihara, H.
Deposit date:2012-05-07
Release date:2012-10-31
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Nat.Struct.Mol.Biol., 19, 2012
4F1H
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BU of 4f1h by Molmil
Crystal structure of TDP2 from Danio rerio complexed with a single strand DNA
Descriptor: DNA (5'-D(P*TP*GP*CP*AP*G)-3'), GLYCEROL, MAGNESIUM ION, ...
Authors:Shi, K, Kurahashi, K, Aihara, H.
Deposit date:2012-05-06
Release date:2012-10-31
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.662 Å)
Cite:Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Nat.Struct.Mol.Biol., 19, 2012
6X6O
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BU of 6x6o by Molmil
Crystal structure of T4 protein Spackle as determined by native SAD phasing
Descriptor: CHLORIDE ION, Protein spackle
Authors:Shi, K, Kurniawan, F, Banerjee, S, Moeller, N.H, Aihara, H.
Deposit date:2020-05-28
Release date:2020-09-16
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Crystal structure of bacteriophage T4 Spackle as determined by native SAD phasing.
Acta Crystallogr D Struct Biol, 76, 2020
6DRT
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BU of 6drt by Molmil
Crystal structure of the processivity clamp GP45 complexed with recognition peptide of ligase from bacteriophage T4
Descriptor: 1,2-ETHANEDIOL, DNA polymerase clamp, GP45 recognition loop
Authors:Shi, K, Aihara, H.
Deposit date:2018-06-13
Release date:2018-09-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.117 Å)
Cite:T4 DNA ligase structure reveals a prototypical ATP-dependent ligase with a unique mode of sliding clamp interaction.
Nucleic Acids Res., 46, 2018
6XC0
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BU of 6xc0 by Molmil
Crystal structure of bacteriophage T4 spackle and lysozyme in monoclinic form
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Shi, K, Oakland, J.T, Kurniawan, F, Moeller, N.H, Aihara, H.
Deposit date:2020-06-07
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Structural basis of superinfection exclusion by bacteriophage T4 Spackle.
Commun Biol, 3, 2020
7UU0
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BU of 7uu0 by Molmil
Crystal structure of the BRD2-BD2 in complex with a ligand
Descriptor: 1,2-ETHANEDIOL, Isoform 3 of Bromodomain-containing protein 2, methyl (7S)-7-(thiophen-2-yl)-1,4-thiazepane-4-carboxylate
Authors:Kalra, P, Shi, K, Aihara, H, Pomerantz, W.C.K.
Deposit date:2022-04-28
Release date:2023-05-03
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the BRD2-BD2 in complex with a ligand
To Be Published
6E8C
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Crystal structure of the double homeodomain of DUX4 in complex with DNA
Descriptor: DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), Double homeobox protein 4
Authors:Lee, J.K, Bosnakovski, D, Toso, E.A, Dinh, T, Banerjee, S, Bohl, T.E, Shi, K, Kurahashi, K, Kyba, M, Aihara, H.
Deposit date:2018-07-27
Release date:2018-12-26
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA.
Cell Rep, 25, 2018
6U82
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Crystal Structure of the Double Homeodomain of DUX4 in Complex with a DNA aptamer containing bulge and loop
Descriptor: DNA (38-MER), Double homeobox protein 4
Authors:Shi, K, Aihara, H.
Deposit date:2019-09-04
Release date:2020-02-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:DNA aptamers against the DUX4 protein reveal novel therapeutic implications for FSHD.
Faseb J., 34, 2020
4NQ3
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Crystal structure of cyanuic acid hydrolase from A. caulinodans
Descriptor: BARBITURIC ACID, Cyanuric acid amidohydrolase, MAGNESIUM ION, ...
Authors:Cho, S, Shi, K, Aihara, H.
Deposit date:2013-11-23
Release date:2014-09-10
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Cyanuric acid hydrolase from Azorhizobium caulinodans ORS 571: crystal structure and insights into a new class of Ser-Lys dyad proteins.
Plos One, 9, 2014
1Z1G
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Crystal structure of a lambda integrase tetramer bound to a Holliday junction
Descriptor: 25-MER, 29-MER, 5'-D(*AP*CP*AP*GP*GP*TP*CP*AP*CP*TP*AP*TP*CP*AP*GP*TP*CP*AP*AP*AP*AP*TP*AP*CP*C)-3', ...
Authors:Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T.
Deposit date:2005-03-03
Release date:2005-06-28
Last modified:2021-10-20
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:A structural basis for allosteric control of DNA recombination by lambda integrase.
Nature, 435, 2005
7TV2
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BU of 7tv2 by Molmil
X-ray crystal structure of HIV-2 CA protein CTD
Descriptor: Capsid protein p24
Authors:Shi, K, Aihara, H.
Deposit date:2022-02-03
Release date:2023-05-17
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation.
J.Mol.Biol., 435, 2023
8EJP
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Crystal structure of the homeodomain of Platypus sDUX in complex with DNA containing 5-Bromouracil
Descriptor: 1,2-ETHANEDIOL, DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), ...
Authors:Yin, L.L, Shi, K, Aihara, H.
Deposit date:2022-09-18
Release date:2023-09-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.174 Å)
Cite:Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein.
Iscience, 26, 2023

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