6ZTS
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6ZTY
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7YI4
| Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in close state | Descriptor: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | Authors: | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | Deposit date: | 2022-07-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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7YI2
| Cryo-EM structure of Rpd3S in loose-state Rpd3S-NCP complex | Descriptor: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | Authors: | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | Deposit date: | 2022-07-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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7YI1
| Cryo-EM structure of Eaf3 CHD bound to H3K36me3 nucleosome | Descriptor: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | Authors: | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | Deposit date: | 2022-07-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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7YI3
| Cryo-EM structure of Rpd3S in close-state Rpd3S-NCP complex | Descriptor: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | Authors: | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | Deposit date: | 2022-07-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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7YI0
| Cryo-EM structure of Rpd3S complex | Descriptor: | Chromatin modification-related protein EAF3, Histone deacetylase RPD3, Transcriptional regulatory protein RCO1, ... | Authors: | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | Deposit date: | 2022-07-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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7YI5
| Cryo-EM structure of Rpd3S complex bound to H3K36me3 nucleosome in loose state | Descriptor: | Chromatin modification-related protein EAF3, Histone H2A, Histone H2B 1.1, ... | Authors: | Li, H.T, Yan, C.Y, Guan, H.P, Wang, P. | Deposit date: | 2022-07-14 | Release date: | 2023-06-14 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Nature, 620, 2023
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1GSQ
| THREE-DIMENSIONAL STRUCTURE, CATALYTIC PROPERTIES AND EVOLUTION OF A SIGMA CLASS GLUTATHIONE TRANSFERASE FROM SQUID, A PROGENITOR OF THE LENS-CRYSTALLINS OF CEPHALOPODS | Descriptor: | GLUTATHIONE S-(2,4 DINITROBENZENE), GLUTATHIONE S-TRANSFERASE | Authors: | Ji, X, Rosenvinge, E.C.V, Armstrong, R.N, Gilliland, G.L. | Deposit date: | 1995-01-09 | Release date: | 1995-06-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods. Biochemistry, 34, 1995
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1GSU
| AN AVIAN CLASS-MU GLUTATHIONE S-TRANSFERASE, CGSTM1-1 AT 1.94 ANGSTROM RESOLUTION | Descriptor: | CLASS-MU GLUTATHIONE S-TRANSFERASE, S-HEXYLGLUTATHIONE | Authors: | Sun, Y.-J, Kuan, C, Tam, M.F, Hsiao, C.-D. | Deposit date: | 1997-09-02 | Release date: | 1998-03-04 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | The three-dimensional structure of an avian class-mu glutathione S-transferase, cGSTM1-1 at 1.94 A resolution. J.Mol.Biol., 278, 1998
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7XE8
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7XR5
| Crystal structure of imine reductase with NAPDH from Streptomyces albidoflavus | Descriptor: | 3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontane-1,59-diol, 6-phosphogluconate dehydrogenase NAD-binding, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhang, J, Chen, R.C, Gao, S.S. | Deposit date: | 2022-05-09 | Release date: | 2022-10-19 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Actinomycetes-derived imine reductases with a preference towards bulky amine substrates. Commun Chem, 5, 2022
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4RIQ
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6L6V
| SPO1 Gp44 N-terminal region (1-55) | Descriptor: | E3 protein | Authors: | Liu, B, Wang, Z. | Deposit date: | 2019-10-29 | Release date: | 2021-05-05 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | A Bacteriophage DNA Mimic Protein Employs a Non-specific Strategy to Inhibit the Bacterial RNA Polymerase. Front Microbiol, 12, 2021
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6MHR
| Structure of the human 4-1BB / Urelumab Fab complex | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, MALONATE ION, ... | Authors: | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | Deposit date: | 2018-09-18 | Release date: | 2018-11-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun, 9, 2018
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6MI2
| Structure of the human 4-1BB / Utomilumab Fab complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... | Authors: | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | Deposit date: | 2018-09-19 | Release date: | 2018-11-21 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.72 Å) | Cite: | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun, 9, 2018
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6MGP
| Structure of human 4-1BB / 4-1BBL complex | Descriptor: | ACETATE ION, GLYCEROL, Tumor necrosis factor ligand superfamily member 9, ... | Authors: | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | Deposit date: | 2018-09-14 | Release date: | 2018-11-14 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab Nat Commun, 9, 2018
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6MGE
| Structure of human 4-1BBL | Descriptor: | GLYCEROL, PHOSPHATE ION, Tumor necrosis factor ligand superfamily member 9 | Authors: | Kimberlin, C.R, Chin, S.M, Roe-Zurz, Z, Xu, A, Yang, Y. | Deposit date: | 2018-09-13 | Release date: | 2018-11-21 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of the 4-1BB/4-1BBL complex and distinct binding and functional properties of utomilumab and urelumab. Nat Commun, 9, 2018
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6NCJ
| Structure of HIV-1 Integrase with potent 5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives Allosteric Site Inhibitors | Descriptor: | (2~{S})-2-[4-(8-fluoranyl-5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)-2-methyl-6-[[(1~{S},2~{R})-2-phenylcyclopropyl]methyl]-7,8-dihydro-5~{H}-1,6-naphthyridin-3-yl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, Integrase, ... | Authors: | Nolte, R.T. | Deposit date: | 2018-12-11 | Release date: | 2019-01-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | 5,6,7,8-Tetrahydro-1,6-naphthyridine Derivatives as Potent HIV-1-Integrase-Allosteric-Site Inhibitors. J. Med. Chem., 62, 2019
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6NO7
| Crystal Structure of the full-length wild-type PKA RIa Holoenzyme | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... | Authors: | Lu, T, Wu, J, Taylor, S.S. | Deposit date: | 2019-01-15 | Release date: | 2019-07-24 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.55 Å) | Cite: | Two PKA RI alpha holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP. Proc.Natl.Acad.Sci.USA, 116, 2019
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6O1D
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6OKO
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6AY9
| Structure of the native full-length HIV-1 capsid protein in complex with CPSF6 peptide | Descriptor: | CHLORIDE ION, Cleavage and polyadenylation specificity factor subunit 6, HIV-1 capsid protein, ... | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-07 | Release date: | 2018-09-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6B2K
| E45A/R132T mutant of HIV-1 capsid protein | Descriptor: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-20 | Release date: | 2018-09-26 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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6AYA
| Structure of the native full-length HIV-1 capsid protein in complex with Nup153 peptide | Descriptor: | CHLORIDE ION, HIV-1 capsid protein, IODIDE ION, ... | Authors: | Gres, A.T, Kirby, K.A, Sarafianos, S.G. | Deposit date: | 2017-09-07 | Release date: | 2018-09-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nat Commun, 14, 2023
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