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5FD0
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BU of 5fd0 by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with NAGlucal
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, B-N-acetylhexosaminidase, GLYCEROL, ...
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2015-12-15
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
5FCZ
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BU of 5fcz by Molmil
Streptomyces plicatus N-acetyl-beta-hexosaminidase in complex with Thio-NAglucal (TNX)
Descriptor: 1,5-anhydro-2-deoxy-2-(ethanethioylamino)-D-arabino-hex-1-enitol, B-N-acetylhexosaminidase, CHLORIDE ION, ...
Authors:Vadlamani, G, Mark, B.L.
Deposit date:2015-12-15
Release date:2016-10-26
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:N-Acetyl glycals are tight-binding and environmentally insensitive inhibitors of hexosaminidases.
Chem.Commun.(Camb.), 52, 2016
2A75
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BU of 2a75 by Molmil
Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
Descriptor: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, SULFATE ION, sialidase
Authors:Amaya, M.F, Alzari, P.M, Buschiazzo, A.
Deposit date:2005-07-04
Release date:2005-11-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.
J.Biol.Chem., 281, 2006
2AM4
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BU of 2am4 by Molmil
Crystal Structure of N-Acetylglucosaminyltransferase I in Complex with UDP-2-deoxy-2-fluoro-glucose
Descriptor: Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, GLYCEROL, MANGANESE (II) ION, ...
Authors:Rini, J.M, Gordon, R.D.
Deposit date:2005-08-08
Release date:2006-06-27
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:X-ray Crystal Structures of Rabbit N-acetylglucosaminyltransferase I (GnT I) in Complex with Donor Substrate Analogues.
J.Mol.Biol., 360, 2006
5GPB
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BU of 5gpb by Molmil
COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor: (1S)-1,5-anhydro-1-(phosphonomethyl)-D-glucitol, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Martin, J.L, Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
8V31
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BU of 8v31 by Molmil
Structure of Alistipes sp. 3-Keto-2-hydroxy-glucal-hydratase AL2
Descriptor: Glycosyl hydrolase, MAGNESIUM ION
Authors:Lazarski, A.C, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2023-11-25
Release date:2024-06-19
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:An alternative broad-specificity pathway for glycan breakdown in bacteria
To Be Published
7ZKC
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BU of 7zkc by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum (apo form)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, UDP-glucose-glycoprotein glucosyltransferase-like protein
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Le Cornu, J.D.
Deposit date:2022-04-12
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.769 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
7ZLU
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BU of 7zlu by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with UDP-2-deoxy-2-fluoro-D-glucose
Descriptor: 1,3-PROPANDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Ibba, R.
Deposit date:2022-04-15
Release date:2022-06-22
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.049 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
7ZLL
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BU of 7zll by Molmil
Catalytic domain of UDP-Glucose Glycoprotein Glucosyltransferase from Chaetomium thermophilum in complex with the 5-[(morpholin-4-yl)methyl]quinolin-8-ol inhibitor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 5-(morpholin-4-ylmethyl)quinolin-8-ol, UDP-glucose-glycoprotein glucosyltransferase-like protein, ...
Authors:Roversi, P, Zitzmann, N, Bayo, Y, Kantsadi, A.L, Chandran, A.V.
Deposit date:2022-04-15
Release date:2023-04-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint.
Iscience, 26, 2023
3VPL
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BU of 3vpl by Molmil
Crystal structure of a 2-fluoroxylotriosyl complex of the Vibrio sp. AX-4 Beta-1,3-xylanase
Descriptor: 3,4-dinitrophenol, Beta-1,3-xylanase XYL4, beta-D-xylopyranose-(1-3)-beta-D-xylopyranose-(1-3)-2-deoxy-2-fluoro-beta-D-xylopyranose, ...
Authors:Watanabe, N, Sakaguchi, K.
Deposit date:2012-03-05
Release date:2013-03-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:The crystal structure of a 2-fluoroxylotriosyl complex of the Vibrio sp. AX-4 beta-1,3-xylanase at 1.2 A resolution
To be Published
1CXK
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BU of 1cxk by Molmil
COMPLEX BETWEEN A MALTONONAOSE SUBSTRATE AND BACILLUS CIRCULANS STRAIN 251 CGTASE E257Q/D229N
Descriptor: CALCIUM ION, PROTEIN (CYCLODEXTRIN-GLYCOSYLTRANSFERASE), alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Uitdehaag, J.C.M, Kalk, K.H, Dijkstra, B.W.
Deposit date:1999-02-24
Release date:1999-05-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family.
Nat.Struct.Biol., 6, 1999
1CXL
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BU of 1cxl by Molmil
COMPLEX BETWEEN A COVALENT INTERMEDIATE AND BACILLUS CIRCULANS STRAIN 251 CGTASE E257Q
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-deoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 4-deoxy-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Uitdehaag, J.C.M, Dijkstra, B.W.
Deposit date:1999-02-27
Release date:1999-05-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:X-ray structures along the reaction pathway of cyclodextrin glycosyltransferase elucidate catalysis in the alpha-amylase family.
Nat.Struct.Biol., 6, 1999
1HP5
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BU of 1hp5 by Molmil
STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE COMPLEXED WITH INTERMEDIATE ANALOUGE NAG-THIAZOLINE
Descriptor: 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, BETA-N-ACETYLHEXOSAMINIDASE, CHLORIDE ION, ...
Authors:Mark, B.L.
Deposit date:2000-12-12
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase.
J.Biol.Chem., 276, 2001
1HNY
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BU of 1hny by Molmil
The structure of human pancreatic alpha-amylase at 1.8 angstroms resolution and comparisons with related enzymes
Descriptor: CALCIUM ION, CHLORIDE ION, HUMAN PANCREATIC ALPHA-AMYLASE
Authors:Luo, Y, Brayer, G.D.
Deposit date:1995-06-28
Release date:1996-03-08
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of human pancreatic alpha-amylase at 1.8 A resolution and comparisons with related enzymes.
Protein Sci., 4, 1995
1HP4
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BU of 1hp4 by Molmil
CRYSTAL STRUCTURE OF STREPTOMYCES PLICATUS BETA-N-ACETYLHEXOSAMINIDASE
Descriptor: BETA-N-ACETYLHEXOSAMINIDASE, CHLORIDE ION, GLYCEROL, ...
Authors:Mark, B.L.
Deposit date:2000-12-12
Release date:2001-04-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystallographic evidence for substrate-assisted catalysis in a bacterial beta-hexosaminidase.
J.Biol.Chem., 276, 2001
6OCN
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BU of 6ocn by Molmil
Montbretin A analogue M06-MbA in complex with Human pancreatic alpha-amylase
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Caner, S, Brayer, G.D.
Deposit date:2019-03-25
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.147 Å)
Cite:Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic alpha-amylase.
Chem Sci, 10, 2019
6OBX
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BU of 6obx by Molmil
Montbretin A analogue M10-MbA in complex with Human pancreatic alpha-amylase
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Caner, S, Brayer, G.D.
Deposit date:2019-03-21
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic alpha-amylase.
Chem Sci, 10, 2019
3GPB
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BU of 3gpb by Molmil
COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor: 1-O-phosphono-alpha-D-glucopyranose, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L, Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990
4X6L
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BU of 4x6l by Molmil
Crystal structure of S. aureus TarM in complex with UDP
Descriptor: TarM, URIDINE-5'-DIPHOSPHATE
Authors:Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C.
Deposit date:2014-12-08
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.19 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7P
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BU of 4x7p by Molmil
Crystal structure of apo S. aureus TarM
Descriptor: SULFATE ION, TarM
Authors:Worrall, L.J, Sobhanifar, S, Gruninger, R.J, Strynadka, N.C.
Deposit date:2014-12-09
Release date:2015-02-18
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7M
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BU of 4x7m by Molmil
Crystal structure of S. aureus TarM G117R mutant in complex with UDP and UDP-GlcNAc
Descriptor: TarM, URIDINE-5'-DIPHOSPHATE, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE
Authors:Worrall, L.J, Sobhanifar, S, Strynadka, N.C.
Deposit date:2014-12-09
Release date:2015-03-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X7R
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BU of 4x7r by Molmil
Crystal structure of S. aureus TarM G117R mutant in complex with Fondaparinux, alpha-GlcNAc-glycerol and UDP
Descriptor: (2S)-2,3-dihydroxypropyl 2-acetamido-2-deoxy-alpha-D-glucopyranoside, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, TarM, ...
Authors:Worrall, L.J, Sobhanifar, S, Strynadka, N.C.
Deposit date:2014-12-09
Release date:2015-02-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structure and mechanism of Staphylococcus aureus TarM, the wall teichoic acid alpha-glycosyltransferase.
Proc.Natl.Acad.Sci.USA, 112, 2015
4X0N
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BU of 4x0n by Molmil
Porcine pancreatic alpha-amylase in complex with helianthamide, a novel proteinaceous inhibitor
Descriptor: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
Authors:Williams, L.K, Brayer, G.D.
Deposit date:2014-11-21
Release date:2015-11-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.6001 Å)
Cite:Structural Templating and Guided Refolding of the Potent Naturally Occurring Peptide Helianthamide Within the Active Site of Amylase, a Diabetes and Obesity Therapeutic Target
To Be Published
7GPB
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BU of 7gpb by Molmil
STRUCTURAL MECHANISM FOR GLYCOGEN PHOSPHORYLASE CONTROL BY PHOSPHORYLATION AND AMP
Descriptor: ADENOSINE MONOPHOSPHATE, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Barford, D, Hu, S.-H, Johnson, L.N.
Deposit date:1990-11-13
Release date:1992-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural mechanism for glycogen phosphorylase control by phosphorylation and AMP.
J.Mol.Biol., 218, 1991
4GPB
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BU of 4gpb by Molmil
COMPARISON OF THE BINDING OF GLUCOSE AND GLUCOSE-1-PHOSPHATE DERIVATIVES TO T-STATE GLYCOGEN PHOSPHORYLASE B
Descriptor: 2-deoxy-2-fluoro-1-O-phosphono-alpha-D-glucopyranose, GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE
Authors:Martin, J.L, Johnson, L.N.
Deposit date:1990-06-04
Release date:1992-10-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Comparison of the binding of glucose and glucose 1-phosphate derivatives to T-state glycogen phosphorylase b.
Biochemistry, 29, 1990

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