2A3J
 
 | | Structure of URNdesign, a complete computational redesign of human U1A protein | | Descriptor: | U1 small nuclear ribonucleoprotein A | | Authors: | Varani, G, Dobson, N, Dantas, G, Baker, D. | | Deposit date: | 2005-06-24 | | Release date: | 2006-06-06 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | High-Resolution Structural Validation of the Computational Redesign of Human U1A Protein
Structure, 14, 2006
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7SHX
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1M82
 | | SOLUTION STRUCTURE OF THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS | | Descriptor: | RNA (25-MER): THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS | | Authors: | Park, C.-J, Bae, S.-H, Lee, M.-K, Varani, G, Choi, B.-S. | | Deposit date: | 2002-07-24 | | Release date: | 2003-06-03 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the influenza A virus cRNA promoter: implications for differential recognition of viral promoter structures by RNA-dependent RNA polymerase
NUCLEIC ACIDS RES., 31, 2003
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7UME
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6DZ9
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6DZC
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1HLX
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5JTK
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6PK9
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2V3M
 | | Structure of the Gar1 domain of NAf1 | | Descriptor: | NAF1, SULFATE ION | | Authors: | Leulliot, N, Godin, K.S, Hoareau-Aveilla, C, Quevillon-Cheruel, S, Varani, G, Henry, Y, van Tilbeurgh, H. | | Deposit date: | 2007-06-19 | | Release date: | 2007-07-10 | | Last modified: | 2011-08-17 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | The Box H/Aca Rnp Assembly Factor Naf1P Contains a Domain Homologous to Gar1P Mediating its Interaction with Cbf5P.
J.Mol.Biol., 371, 2007
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7VRL
 | | Solution structure of Rbfox RRM bound to a non-cognate RNA | | Descriptor: | RNA (5'-R(*UP*GP*CP*AP*UP*AP*U)-3'), RNA binding protein fox-1 homolog 1 | | Authors: | Yang, F, Varani, G. | | Deposit date: | 2021-10-23 | | Release date: | 2022-10-26 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Two distinct binding modes provide the RNA-binding protein RbFox with extraordinary sequence specificity.
Nat Commun, 14, 2023
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7UMD
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7UMC
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4M3O
 | | Crystal structure of K.lactis Rtr1 NTD | | Descriptor: | KLLA0F12672p, ZINC ION | | Authors: | Hsu, P.L, Yang, W, Zheng, N, Varani, G. | | Deposit date: | 2013-08-06 | | Release date: | 2014-07-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Rtr1 Is a Dual Specificity Phosphatase That Dephosphorylates Tyr1 and Ser5 on the RNA Polymerase II CTD.
J.Mol.Biol., 426, 2014
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1QC8
 | | NMR STRUCTURE OF TAU EXON 10 SPLICING REGULATORY ELEMENT RNA | | Descriptor: | TAU EXON 10 SPLICING REGULATORY ELEMENT RNA | | Authors: | Varani, L, Spillantini, M.G, Klug, A, Goedert, M, Varani, G. | | Deposit date: | 1999-05-18 | | Release date: | 1999-08-31 | | Last modified: | 2022-03-02 | | Method: | SOLUTION NMR | | Cite: | Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17.
Proc.Natl.Acad.Sci.USA, 96, 1999
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1FHT
 | | RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES | | Descriptor: | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A | | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | | Deposit date: | 1996-02-21 | | Release date: | 1996-07-11 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding.
J.Mol.Biol., 257, 1996
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6MXQ
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6NOA
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2FEY
 | | The structure of stem loop IV of Tetrahymena telomerase RNA | | Descriptor: | stem-loop IV of Tetrahymena telomerase RNA | | Authors: | Chen, Y, Fender, J, Legassie, J.D, Jarstfer, M.B, Bryan, T.M, Varani, G. | | Deposit date: | 2005-12-16 | | Release date: | 2006-06-27 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Structure of stem-loop IV of Tetrahymena telomerase RNA.
Embo J., 25, 2006
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6W3M
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6U79
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1UUI
 | | NMR structure of a synthetic small molecule, rbt158, bound to HIV-1 TAR RNA | | Descriptor: | 4-[AMINO(IMINO)METHYL]-1-[2-(3-AMMONIOPROPOXY)-5-METHOXYBENZYL]PIPERAZIN-1-IUM, 5'-R(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP*CP* CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C)-3' | | Authors: | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | | Deposit date: | 2003-12-19 | | Release date: | 2004-02-12 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
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1UUD
 | | NMR structure of a synthetic small molecule, rbt203, bound to HIV-1 TAR RNA | | Descriptor: | N-[2-(2-{[(4-{[AMINO(IMINO)METHYL]AMINO}BUTYL)AMINO]METHYL}-4-METHOXYPHENOXY)ETHYL]GUANIDINE, RNA (5'-(*GP*GP*CP*AP*GP*AP*UP*CP*UP*GP*AP*GP *CP*CP*UP*GP*GP*GP*AP*GP*CP*UP*CP*UP*CP*UP*GP*CP*C) -3') | | Authors: | Davis, B, Afshar, M, Varani, G, Karn, J, Murchie, A.I.H, Lentzen, G, Drysdale, M.J, Potter, A.J, Bower, J, Aboul-Ela, F. | | Deposit date: | 2003-12-18 | | Release date: | 2004-03-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Rational Design of Inhibitors of HIV-1 Tar RNA Through the Stabilisation of Electrostatic "Hot Spots"
J.Mol.Biol., 336, 2004
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3ZUZ
 | | Structure of Shq1p C-terminal domain | | Descriptor: | ISOPROPYL ALCOHOL, PROTEIN SHQ1 | | Authors: | Walbott, H, Machado-Pinilla, R, Liger, D, Blaud, M, Rety, S, Grozdanov, P.N, Godin, K, vanTilbeurgh, H, Varani, G, Meier, U.T, Leulliot, N. | | Deposit date: | 2011-07-22 | | Release date: | 2011-11-30 | | Last modified: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The H/Aca Rnp Assembly Factor Shq1 Functions as an RNA Mimic.
Genes Dev., 25, 2011
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7K4L
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