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6RX8
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BU of 6rx8 by Molmil
EDDS lyase variant D290M/Y320M with bound fumarate
Descriptor: Argininosuccinate lyase, FUMARIC ACID, SODIUM ION
Authors:Grandi, E, Poelarends, G.J, Thunnissen, A.M.W.H.
Deposit date:2019-06-07
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners.
Angew.Chem.Int.Ed.Engl., 59, 2020
6RXA
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BU of 6rxa by Molmil
EDDS lyase variant D290M/Y320M with bound formate
Descriptor: Argininosuccinate lyase, FORMIC ACID, GLYCEROL, ...
Authors:Grandi, E, Poelarends, G.J, Thunnissen, A.M.W.H.
Deposit date:2019-06-07
Release date:2019-10-30
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:Engineered C-N Lyase: Enantioselective Synthesis of Chiral Synthons for Artificial Dipeptide Sweeteners.
Angew.Chem.Int.Ed.Engl., 59, 2020
6S9V
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BU of 6s9v by Molmil
Crystal structure of sucrose 6F-phosphate phosphorylase from Thermoanaerobacter thermosaccharolyticum
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, HEXAETHYLENE GLYCOL, ...
Authors:Capra, N, Franceus, J, Desmet, T, Thunnissen, A.M.W.H.
Deposit date:2019-07-15
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Structural Comparison of a Promiscuous and a Highly Specific Sucrose 6 F -Phosphate Phosphorylase.
Int J Mol Sci, 20, 2019
6S9U
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BU of 6s9u by Molmil
Crystal structure of sucrose 6F-phosphate phosphorylase from Ilumatobacter coccineus
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ...
Authors:Capra, N, Franceus, J, Desmet, T, Thunnissen, A.M.W.H.
Deposit date:2019-07-15
Release date:2019-08-28
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Comparison of a Promiscuous and a Highly Specific Sucrose 6 F -Phosphate Phosphorylase.
Int J Mol Sci, 20, 2019
6TB0
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BU of 6tb0 by Molmil
Crystal structure of thermostable omega transaminase 4-fold mutant from Pseudomonas jessenii
Descriptor: Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
Deposit date:2019-10-31
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Robust omega-Transaminases by Computational Stabilization of the Subunit Interface.
Acs Catalysis, 10, 2020
6TB1
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BU of 6tb1 by Molmil
Crystal structure of thermostable omega transaminase 6-fold mutant from Pseudomonas jessenii
Descriptor: Aspartate aminotransferase family protein, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:Capra, N, Rozeboom, H.J, Thunnissen, A.M.W.H, Janssen, D.B.
Deposit date:2019-10-31
Release date:2020-07-15
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Robust omega-Transaminases by Computational Stabilization of the Subunit Interface.
Acs Catalysis, 10, 2020
6GK5
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BU of 6gk5 by Molmil
Crystal structure of cytochrome P450 CYP267B1 from Sorangium cellulosum So ce56
Descriptor: Cytochrome P450 CYP267B1 protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2018-05-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1.
Biochem. J., 475, 2018
6GK6
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BU of 6gk6 by Molmil
Crystal structure of myxobacterial cytochrome P450 CYP267B1 in complex with myristic acid
Descriptor: Cytochrome P450 CYP267B1 protein, MYRISTIC ACID, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2018-05-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1.
Biochem. J., 475, 2018
6I8N
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BU of 6i8n by Molmil
Crystal structure of LmrR with V15 replaced by unnatural amino acid 4-amino-L-phenylalanine
Descriptor: 3[N-MORPHOLINO]PROPANE SULFONIC ACID, Transcriptional regulator, PadR-like family
Authors:Reddem, R, Thunnissen, A.M.W.H.
Deposit date:2018-11-20
Release date:2019-01-02
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid.
Angew. Chem. Int. Ed. Engl., 58, 2019
5L94
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BU of 5l94 by Molmil
The 2.25 A crystal structure of CYP109E1 from Bacillus megaterium in complex with testosterone
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, TESTOSTERONE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2016-06-09
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
5L91
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BU of 5l91 by Molmil
The 2.2 A crystal structure of CYP109E1 from Bacillus megaterium bound with four corticosterone molecules
Descriptor: CORTICOSTERONE, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2016-06-09
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
5L92
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BU of 5l92 by Molmil
The 2.1 A crystal structure of CYP109E1 from Bacillus megaterium in complex with corticosterone
Descriptor: CORTICOSTERONE, Cytochrome P450, MALONIC ACID, ...
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2016-06-09
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
5L90
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BU of 5l90 by Molmil
The crystal structure of substrate-free CYP109E1 from Bacillus megaterium at 2.55 Angstrom resolution
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2016-06-09
Release date:2016-10-05
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural basis of steroid binding and oxidation by the cytochrome P450 CYP109E1 from Bacillus megaterium.
Febs J., 283, 2016
6F88
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BU of 6f88 by Molmil
Crystal structure of cytochrome P450 CYP260A1 (S276N) bound with progesterone
Descriptor: Cytochrome P450 CYP260A1, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2017-12-12
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
ACS Chem. Biol., 13, 2018
6F8C
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BU of 6f8c by Molmil
Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with progesterone
Descriptor: Cytochrome P450 CYP260A1, PROGESTERONE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2017-12-12
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
ACS Chem. Biol., 13, 2018
6F85
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BU of 6f85 by Molmil
Crystal structure of cytochrome P450 CYP260A1 (S276N) bound with histidine
Descriptor: Cytochrome P450 CYP260A1, HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2017-12-12
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
ACS Chem. Biol., 13, 2018
6F8A
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BU of 6f8a by Molmil
Crystal structure of cytochrome P450 CYP260A1 (S276I) bound with histidine
Descriptor: Cytochrome P450 CYP260A1, HISTIDINE, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2017-12-12
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structure-Based Engineering of Steroidogenic CYP260A1 for Stereo- and Regioselective Hydroxylation of Progesterone.
ACS Chem. Biol., 13, 2018
5MDX
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BU of 5mdx by Molmil
Cryo-EM structure of the PSII supercomplex from Arabidopsis thaliana
Descriptor: CHLOROPHYLL A, CHLOROPHYLL B, Chlorophyll a-b binding protein 1, ...
Authors:van Bezouwen, L.S, Caffarri, S, Kale, R.S, Kouril, R, Thunnissen, A.M.W.H, Oostergetel, G.T, Boekema, E.J.
Deposit date:2016-11-13
Release date:2017-06-21
Last modified:2019-04-24
Method:ELECTRON MICROSCOPY (5.3 Å)
Cite:Subunit and chlorophyll organization of the plant photosystem II supercomplex.
Nat Plants, 3, 2017
6FPS
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BU of 6fps by Molmil
Crystal structure of 4-oxalocrotonate tautomerase triple mutant L8Y/M45Y/F50A
Descriptor: 2-hydroxymuconate tautomerase, GLYCEROL, PHOSPHATE ION
Authors:Pijning, T, Thunnissen, A.M.W.H.
Deposit date:2018-02-12
Release date:2019-03-06
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Enantioselective Synthesis of Pharmaceutically Active gamma-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions.
ACS Catal, 9, 2019
6FUU
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BU of 6fuu by Molmil
Transcriptional regulator LmrR with bound heme
Descriptor: PROTOPORPHYRIN IX CONTAINING FE, Transcriptional regulator PadR family
Authors:Reddem, E.R, Thunnissen, A.M.W.H.
Deposit date:2018-02-27
Release date:2018-05-16
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:An Artificial Heme Enzyme for Cyclopropanation Reactions.
Angew. Chem. Int. Ed. Engl., 57, 2018
4U5R
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BU of 4u5r by Molmil
Crystal structure of D106A mutant of RhCC (YP_702633.1) from Rhodococcus jostii RHA1 at 1.55 Angstrom
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, RhCC
Authors:Poddar, H, Rozeboom, H.J, Thunnissen, A.M.W.H.
Deposit date:2014-07-25
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Functional and structural characterization of an unusual cofactor-independent oxygenase.
Biochemistry, 54, 2015
4U5P
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BU of 4u5p by Molmil
Crystal structure of native RhCC (YP_702633.1) from Rhodococcus jostii RHA1 at 1.78 Angstrom
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, MAGNESIUM ION, ...
Authors:Poddar, H, Rozeboom, H.J, Thunnissen, A.M.W.H.
Deposit date:2014-07-25
Release date:2015-02-25
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.782 Å)
Cite:Functional and structural characterization of an unusual cofactor-independent oxygenase.
Biochemistry, 54, 2015
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