5F8J
 
 | | Enterovirus 71 Polymerase Elongation Complex (C1S4 Form) | | Descriptor: | GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... | | Authors: | Shu, B, Gong, P. | | Deposit date: | 2015-12-09 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.675 Å) | | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
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5F8L
 | | Enterovirus 71 Polymerase Elongation Complex (C3S1 Form) | | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... | | Authors: | Shu, B, Gong, P. | | Deposit date: | 2015-12-09 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.812 Å) | | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
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5F8H
 | | Enterovirus 71 Polymerase Elongation Complex (C1S1/2 Form) | | Descriptor: | Genome polyprotein, MAGNESIUM ION, RNA (35-MER), ... | | Authors: | Shu, B, Gong, P. | | Deposit date: | 2015-12-09 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.45 Å) | | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
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5F8N
 | | Enterovirus 71 Polymerase Elongation Complex (C3S6 Form) | | Descriptor: | GLYCEROL, Genome polyprotein, PYROPHOSPHATE 2-, ... | | Authors: | Shu, B, Gong, P. | | Deposit date: | 2015-12-09 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.484 Å) | | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
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5F8G
 | | Enterovirus 71 Polymerase Elongation Complex (C1S1 Form) | | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... | | Authors: | Shu, B, Gong, P. | | Deposit date: | 2015-12-09 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.78 Å) | | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
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5F8I
 | | Enterovirus 71 Polymerase Elongation Complex (C1S2/3 Form) | | Descriptor: | CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, Genome polyprotein, ... | | Authors: | Shu, B, Gong, P. | | Deposit date: | 2015-12-09 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.503 Å) | | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
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5F8M
 | | Enterovirus 71 Polymerase Elongation Complex (C3S4/5 Form) | | Descriptor: | GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... | | Authors: | Shu, B, Gong, P. | | Deposit date: | 2015-12-09 | | Release date: | 2016-06-22 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.83 Å) | | Cite: | Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
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7WUT
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7WUV
 | | CryoEM structure of sNS1 hexamer | | Descriptor: | Core protein | | Authors: | Shu, B, Ooi, J.S.G, Lok, S.M. | | Deposit date: | 2022-02-09 | | Release date: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (8 Å) | | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
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7WUR
 | | CryoEM structure of sNS1 complexed with Fab5E3 | | Descriptor: | Core protein, Fab 5E3 Heavy Chain, Fab 5E3 Light Chain | | Authors: | Shu, B, Lok, S.M. | | Deposit date: | 2022-02-09 | | Release date: | 2022-12-21 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
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7WUS
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7WUU
 | | CryoEM structure of loose sNS1 tetramer | | Descriptor: | Core protein | | Authors: | Shu, B, Lok, S.M. | | Deposit date: | 2022-02-09 | | Release date: | 2022-12-21 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (8.3 Å) | | Cite: | CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever.
Nat Commun, 13, 2022
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7YAR
 | | ZIKV_Fab_G9E | | Descriptor: | E protein, M protein, heavy chain, ... | | Authors: | Shu, B, Thiam-Seng, N, Lok, S. | | Deposit date: | 2022-06-28 | | Release date: | 2023-01-04 | | Last modified: | 2023-08-02 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Structure and neutralization mechanism of a human antibody targeting a complex Epitope on Zika virus.
Plos Pathog., 19, 2023
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7V3I
 | | DENV2_NGC_Fab_C10 4degrees (3Fab:3E) | | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3J
 | | DENV2:F(ab')2-local | | Descriptor: | Envelope protein E, Fab_C10_heavy_chain, Fab_C10_light_chain, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3F
 | | DENV2_NGC_Fab_C10 28degree (1Fab:3E) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3G
 | | DENV2_NGC_Fab_C10 28degrees (2Fab:3E) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope protein E, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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7V3H
 | | DENV2_NGC_Fab_C10 28degrees (3Fab:3E) | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C10 IgG heavy chain variable region, ... | | Authors: | Shu, B, Zhang, S, Victor, A.K, Ng, T.S, Lok, S.M. | | Deposit date: | 2021-08-10 | | Release date: | 2021-12-29 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Human antibody C10 neutralizes by diminishing Zika but enhancing dengue virus dynamics.
Cell, 184, 2021
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5Y6Z
 | | Crystal structure of the coxsackievirus A16 polymerase elongation complex | | Descriptor: | GLYCEROL, Genome polyprotein, MAGNESIUM ION, ... | | Authors: | Bi, P, Shu, B, Gong, P. | | Deposit date: | 2017-08-15 | | Release date: | 2017-12-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Crystal structure of the coxsackievirus A16 RNA-dependent RNA polymerase elongation complex reveals novel features in motif A dynamics
Virol Sin, 32, 2017
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6LSE
 | | Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form) | | Descriptor: | Genome polyprotein, PYROPHOSPHATE 2-, RNA (35-MER), ... | | Authors: | Wang, M, Shu, B, Jing, X, Gong, P. | | Deposit date: | 2020-01-17 | | Release date: | 2020-04-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
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6LSF
 | | Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form) | | Descriptor: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ... | | Authors: | Wang, M, Shu, B, Jing, X, Gong, P. | | Deposit date: | 2020-01-17 | | Release date: | 2020-04-29 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.152 Å) | | Cite: | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
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7CW3
 | | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | | Deposit date: | 2020-08-27 | | Release date: | 2020-11-04 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (9.4 Å) | | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7CW0
 | | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG | | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | | Deposit date: | 2020-08-27 | | Release date: | 2020-11-04 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (5.9 Å) | | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7CW2
 | | Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 (subregion around icosahedral 5-fold vertex) | | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | | Deposit date: | 2020-08-27 | | Release date: | 2020-11-04 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
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7CVZ
 | | Cryo-EM structure of Chikungunya virus in complex with Fab fragments of mAb CHK-263 | | Descriptor: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | | Authors: | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | | Deposit date: | 2020-08-27 | | Release date: | 2020-11-04 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
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