3CSP
| Crystal structure of the DM2 mutant of myelin oligodendrocyte glycoprotein | Descriptor: | Myelin-oligodendrocyte glycoprotein | Authors: | Breithaupt, C, Schafer, B, Pellkofer, H, Huber, R, Linington, C, Jacob, U. | Deposit date: | 2008-04-10 | Release date: | 2008-10-21 | Last modified: | 2021-10-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Demyelinating myelin oligodendrocyte glycoprotein-specific autoantibody response is focused on one dominant conformational epitope region in rodents J.Immunol., 181, 2008
|
|
1P4W
| Solution structure of the DNA-binding domain of the Erwinia amylovora RcsB protein | Descriptor: | rcsB | Authors: | Pristovsek, P, Sengupta, K, Loehr, F, Schaefer, B, Wehland von Trebra, M, Rueterjans, H, Bernhard, F. | Deposit date: | 2003-04-24 | Release date: | 2003-06-17 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural analysis of the DNA-binding domain of the Erwinia amylovora RcsB protein and its interaction with the RcsAB box. J.Biol.Chem., 278, 2003
|
|
5N2O
| Structure Of P63 SAM Domain L514F Mutant Causative Of AEC Syndrome | Descriptor: | Tumor protein 63 | Authors: | Rinnenthal, J, Wuerz, J.M, Osterburg, C, Guentert, P, Doetsch, V. | Deposit date: | 2017-02-08 | Release date: | 2018-02-07 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Protein aggregation of the p63 transcription factor underlies severe skin fragility in AEC syndrome. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
6FGN
| Solution Structure of p300Taz2-p63TA | Descriptor: | Histone acetyltransferase p300,Tumor protein 63, ZINC ION | Authors: | Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V. | Deposit date: | 2018-01-11 | Release date: | 2018-05-30 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain. Structure, 26, 2018
|
|
6FGS
| Solution structure of p300Taz2-p73TA1 | Descriptor: | Histone acetyltransferase p300,Tumor protein p73, ZINC ION | Authors: | Gebel, J, Kazemi, S, Lohr, F, Guntert, P, Dotsch, V. | Deposit date: | 2018-01-11 | Release date: | 2018-05-30 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Regulation of the Activity in the p53 Family Depends on the Organization of the Transactivation Domain. Structure, 26, 2018
|
|
5HOB
| p73 homo-tetramerization domain mutant I | Descriptor: | MAGNESIUM ION, Tumor protein p73 | Authors: | Coutandin, D, Krojer, T, Salah, E, Mathea, S, Knapp, S, Dotsch, V. | Deposit date: | 2016-01-19 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.220013 Å) | Cite: | Structural basis of p63/p73 hetero-tetramerization To Be Published
|
|
5HOC
| p73 homo-tetramerization domain mutant II | Descriptor: | Tumor protein p73 | Authors: | Coutandin, D, Krojer, T, Salah, E, Mathea, S, Sumyk, M, Knapp, S, Dotsch, V. | Deposit date: | 2016-01-19 | Release date: | 2016-10-19 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.36007786 Å) | Cite: | Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ., 23, 2016
|
|
7Z7E
| Crystal structure of p63 DNA binding domain in complex with inhibitory DARPin G4 | Descriptor: | DARPIN, Isoform 4 of Tumor protein 63, ZINC ION | Authors: | Strubel, A, Gebel, J, Chaikuad, A, Muenick, P, Doetsch, V. | Deposit date: | 2022-03-15 | Release date: | 2022-06-29 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
|
|
7Z71
| Crystal structure of p63 DBD in complex with darpin C14 | Descriptor: | Darpin C14, Isoform 4 of Tumor protein 63, ZINC ION | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2022-03-14 | Release date: | 2022-07-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
|
|
7Z72
| Crystal structure of p63 SAM in complex with darpin A5 | Descriptor: | DI(HYDROXYETHYL)ETHER, Darpin A5, Isoform 9 of Tumor protein 63 | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2022-03-14 | Release date: | 2022-07-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
|
|
7Z73
| Crystal structure of p63 tetramerization domain in complex with darpin 8F1 | Descriptor: | Darpin 8F1, Isoform 2 of Tumor protein 63 | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2022-03-14 | Release date: | 2022-07-06 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Designed Ankyrin Repeat Proteins as a tool box for analyzing p63. Cell Death Differ., 29, 2022
|
|
2KBY
| The Tetramerization Domain of Human p73 | Descriptor: | Tumor protein p73 | Authors: | Coutandin, D, Ikeya, T, Loehr, F, Guntert, P, Ou, H.D, Doetsch, V. | Deposit date: | 2008-12-12 | Release date: | 2009-09-29 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Conformational stability and activity of p73 require a second helix in the tetramerization domain. Cell Death Differ., 16, 2009
|
|
2M8J
| Structure of Pin1 WW domain phospho-mimic S16E | Descriptor: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Luh, L.M, Kirchner, D.K, Loehr, F, Haensel, R, Doetsch, V. | Deposit date: | 2013-05-22 | Release date: | 2014-04-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition. J.Am.Chem.Soc., 135, 2013
|
|
2M8I
| Structure of Pin1 WW domain | Descriptor: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Authors: | Luh, L.M, Kirchner, D.K, Loehr, F, Haensel, R, Doetsch, V. | Deposit date: | 2013-05-22 | Release date: | 2014-04-09 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Molecular crowding drives active Pin1 into nonspecific complexes with endogenous proteins prior to substrate recognition. J.Am.Chem.Soc., 135, 2013
|
|
2NB1
| P63/p73 hetero-tetramerisation domain | Descriptor: | Tumor protein 63, Tumor protein p73 | Authors: | Gebel, J, Buchner, L, Loehr, F.M, Luh, L.M, Coutandin, D, Guentert, P, Doetsch, V. | Deposit date: | 2016-01-19 | Release date: | 2016-12-07 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Mechanism of TAp73 inhibition by Delta Np63 and structural basis of p63/p73 hetero-tetramerization. Cell Death Differ., 23, 2016
|
|
8P9C
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | Descriptor: | 1,2-ETHANEDIOL, Darpin 1810 F11, Tumor protein 63, ... | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-06-05 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
|
|
8P9D
| Crystal structure of p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 A2 | Descriptor: | Darpin 1810 A2, Tumor protein 63, Tumor protein p73 | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-06-05 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
|
|
8P9E
| Crystal structure of wild type p63-p73 heterotetramer (tetramerisation domain) in complex with darpin 1810 F11 | Descriptor: | Darpin 1810 F11, GLYCEROL, Isoform 2 of Tumor protein 63, ... | Authors: | Chaikuad, A, Strubel, A, Doetsch, V, Knapp, S, Structural Genomics Consortium (SGC) | Deposit date: | 2023-06-05 | Release date: | 2023-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | DARPins detect the formation of hetero-tetramers of p63 and p73 in epithelial tissues and in squamous cell carcinoma. Cell Death Dis, 14, 2023
|
|