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8R8D
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BU of 8r8d by Molmil
Cryo-EM structure of coagulation factor beta-XIIa in complex with the garadacimab Fab fragment (symmetric dimer)
Descriptor: Coagulation factor XII, Garadacimab heavy chain variable region, Garadacimab light chain variable region, ...
Authors:Drulyte, I.
Deposit date:2023-11-29
Release date:2023-12-13
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural basis for inhibition of beta-FXIIa by garadacimab
To Be Published
4DUR
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BU of 4dur by Molmil
The X-ray Crystal Structure of Full-Length type II Human Plasminogen
Descriptor: ACETATE ION, BICARBONATE ION, CHLORIDE ION, ...
Authors:Law, R.H.P, Caradoc-Davies, T, Whisstock, J.C.
Deposit date:2012-02-22
Release date:2012-03-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:The X-ray crystal structure of full-length human plasminogen
Cell Rep, 1, 2012
4DUU
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BU of 4duu by Molmil
The X-ray Crystal Structure of Full-Length type I Human Plasminogen
Descriptor: Plasminogen
Authors:Law, R.H.P, Caradoc-Davies, T, Whisstock, J.C.
Deposit date:2012-02-22
Release date:2012-03-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (5.2 Å)
Cite:The X-ray crystal structure of full-length human plasminogen
Cell Rep, 1, 2012
5UGG
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BU of 5ugg by Molmil
Protease Inhibitor
Descriptor: Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(quinolin-2-yl)methyl]-L-tyrosinamide, Plasminogen
Authors:Law, R.H.P, Wu, G, Whisstock, J.C.
Deposit date:2017-01-08
Release date:2017-05-31
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors.
Blood Adv, 1, 2017
5UGD
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BU of 5ugd by Molmil
Protease Inhibitor
Descriptor: Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(pyridin-4-yl)methyl]-L-tyrosinamide, Plasminogen
Authors:Law, R.H.P, Wu, G, Whisstock, J.C.
Deposit date:2017-01-08
Release date:2017-05-31
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors.
Blood Adv, 1, 2017
6OG4
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BU of 6og4 by Molmil
plasminogen binding group A streptococcal M protein
Descriptor: Plasminogen, Plasminogen-binding group A streptococcal M-like protein PAM, SULFATE ION
Authors:Law, R.H.P, Quek, A.J, Whisstock, J.C, Caradoc-Davies, T.T.
Deposit date:2019-04-01
Release date:2019-07-24
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding.
J.Mol.Biol., 431, 2019
6NMB
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BU of 6nmb by Molmil
Tranexamic Acid is an Active Site Inhibitor of Urokinase Plasminogen Activator
Descriptor: NITRATE ION, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID, Urokinase-type plasminogen activator
Authors:Law, R.H.P, Wu, G.
Deposit date:2019-01-10
Release date:2019-03-06
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Tranexamic acid is an active site inhibitor of urokinase plasminogen activator.
Blood Adv, 3, 2019

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