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7PMY
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BU of 7pmy by Molmil
HsPepT2 bound to Ala-Phe in the inward facing partially occluded conformation
Descriptor: ALA-PHE, Solute carrier family 15 member 2
Authors:Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C.
Deposit date:2021-09-04
Release date:2021-10-20
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes.
Sci Adv, 7, 2021
7PMX
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BU of 7pmx by Molmil
HsPepT1 bound to Ala-Phe in the outward facing open conformation
Descriptor: ALA-PHE, Solute carrier family 15 member 1
Authors:Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C.
Deposit date:2021-09-03
Release date:2021-10-20
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes.
Sci Adv, 7, 2021
7PMW
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BU of 7pmw by Molmil
HsPepT1 bound to Ala-Phe in the outward facing occluded conformation
Descriptor: ALA-PHE, Solute carrier family 15 member 1
Authors:Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C.
Deposit date:2021-09-03
Release date:2021-10-20
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes.
Sci Adv, 7, 2021
7PN1
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BU of 7pn1 by Molmil
Apo HsPepT1 in the outward facing open conformation
Descriptor: Solute carrier family 15 member 1
Authors:Killer, M, Wald, J, Pieprzyk, J, Marlovits, T.C, Loew, C.
Deposit date:2021-09-04
Release date:2021-10-20
Last modified:2021-11-17
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural snapshots of human PepT1 and PepT2 reveal mechanistic insights into substrate and drug transport across epithelial membranes.
Sci Adv, 7, 2021
6EZI
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BU of 6ezi by Molmil
PDZK1 domain 4 in complex with C-terminal peptide of human PepT2.
Descriptor: GLYCEROL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Solute carrier family 15 member 2
Authors:Loew, C, Flayhan, A, Pieprzyk, J.
Deposit date:2017-11-15
Release date:2018-09-26
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.503321 Å)
Cite:Probing the Architecture of a Multi-PDZ Domain Protein: Structure of PDZK1 in Solution.
Structure, 26, 2018
7A25
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BU of 7a25 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-08-16
Release date:2020-11-25
Method:ELECTRON MICROSCOPY (3.06 Å)
Cite:Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.
Nat Commun, 11, 2020
7A29
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BU of 7a29 by Molmil
Cryo-EM structure of the SARS-CoV-2 spike protein bound to neutralizing sybodies (Sb23) 2-up conformation
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Neutralising sybody (Sb23), ...
Authors:Hallberg, B.M, Das, H.
Deposit date:2020-08-16
Release date:2020-10-21
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (2.94 Å)
Cite:Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2.
Nat Commun, 11, 2020
6EIA
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BU of 6eia by Molmil
PepTSt in complex with HEPES (100 mM)
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-18
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5OXM
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BU of 5oxm by Molmil
PepTSt in complex with dipeptide Asp-Glu
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ASPARTIC ACID, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-07
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.295 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5OXK
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BU of 5oxk by Molmil
PepTSt in complex with dipeptide Ala-Gln
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-07
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5OXN
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BU of 5oxn by Molmil
PepTSt in complex with dipeptide Phe-Ala
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, ALANINE, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-07
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5OXQ
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BU of 5oxq by Molmil
PepTSt in complex with HEPES (300 mM)
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-07
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.195 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5OXO
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BU of 5oxo by Molmil
PepTSt apo structure
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, CITRIC ACID, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-07
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5OXP
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BU of 5oxp by Molmil
PepTSt in occluded conformation with phosphate ion bound
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, Di-or tripeptide:H+ symporter, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-07
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.372 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018
5OXL
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BU of 5oxl by Molmil
PepTSt in complex with dipeptide Ala-Leu
Descriptor: (2R)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, (2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Martinez Molledo, M, Quistgaard, E.M, Loew, C.
Deposit date:2017-09-07
Release date:2018-02-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Multispecific Substrate Recognition in a Proton-Dependent Oligopeptide Transporter.
Structure, 26, 2018

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