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1W6G
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BU of 1w6g by Molmil
AGAO holoenzyme at 1.55 angstroms
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Langley, D.B, Duff, A.P, Juda, G.A, Shepard, E.M, Dooley, D.M, Freeman, H.C, Guss, J.M.
Deposit date:2004-08-18
Release date:2005-12-08
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The Copper Containing Amine Oxidase from Arthrobacter Globiformis: Refinement at 1.55 And 2.20 A Resolution in Two Crystal Forms.
Acta Crystallogr.,Sect.F, 62, 2006
4X4X
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BU of 4x4x by Molmil
Retrofitting antibodies with stabilizing mutations. Herceptin scFv mutant.
Descriptor: Human Variable Heavy Chain of Herceptin, Human Variable Light Chain of Herceptin
Authors:Langley, D.B, Roome, B, Christ, D.
Deposit date:2014-12-04
Release date:2015-12-23
Last modified:2020-01-08
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Retrofitting antibodies with stabilizing mutations
To Be Published
4X4Z
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BU of 4x4z by Molmil
Retrofitting antibodies with stabilizing mutations. Herceptin VL mutant F53D.
Descriptor: Herceptin VL domain with F53D mutation
Authors:Langley, D.B, Rouet, R, Christ, D.
Deposit date:2014-12-04
Release date:2015-12-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Retrofitting antibodies with stabilizing mutations
To Be Published
7RTA
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BU of 7rta by Molmil
Crystal structures of human PYY and NPY
Descriptor: 4A3B2-B Fab heavy chain, 4A3B2-B Fab light chain, Neuropeptide Y, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2021-08-12
Release date:2022-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
7RT9
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BU of 7rt9 by Molmil
Crystal structures of human PYY and NPY
Descriptor: 4A3B2-A Fab heavy chain, 4A3B2-A Fab light chain, GLYCEROL, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2021-08-12
Release date:2022-03-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of human neuropeptide Y (NPY) and peptide YY (PYY).
Neuropeptides, 92, 2022
2ZCG
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BU of 2zcg by Molmil
Structure and inhibition of orotidine 5'-phosphate decarboxylase from plasmodium falciparum
Descriptor: Orotidine 5'-phosphate decarboxylase
Authors:Langley, D.B, Guss, J.M, Shojaei, M, Christopherson, R.I.
Deposit date:2007-11-08
Release date:2008-03-11
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.223 Å)
Cite:Structure and Inhibition of Orotidine 5'-Monophosphate Decarboxylase from Plasmodium falciparum
Biochemistry, 47, 2008
7UEN
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BU of 7uen by Molmil
Genetic and structural basis of the human anti-alpha-galactosyl antibody response
Descriptor: M86 antibody Fab heavy chain, M86 antibody Fab light chain, PHOSPHATE ION, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-03-22
Release date:2022-06-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UEL
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BU of 7uel by Molmil
Genetic and structural basis for the human anti-alpha-galactosyl antibody response
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Heavy chain Fab of antibody JEC1, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-03-22
Release date:2022-06-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
7UEM
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BU of 7uem by Molmil
Genomic and structural basis for the human anti-alpha-galactosyl antibody response
Descriptor: CHLORIDE ION, Heavy chain Fab arm of antibody HKB7, Light chain Fab of antibody HKB7, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-03-22
Release date:2022-06-29
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.314 Å)
Cite:Genetic and structural basis of the human anti-alpha-galactosyl antibody response.
Proc.Natl.Acad.Sci.USA, 119, 2022
8CWI
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BU of 8cwi by Molmil
Fab arm of antibody 10G4 bound to CoV-2 receptor binding domain (RBD)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Heavy chain of Fab arm of antibody 10G4, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-05-19
Release date:2023-05-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.873 Å)
Cite:Neutralization of CoV-2 omicron lineages by affinity-matured class 5 antibodies
To Be Published
8CWK
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BU of 8cwk by Molmil
Fab arm of antibodies 4G1-C2 and 10G4 bound to CoV-2 receptor binding domain (RBD)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Heavy chain of Fab arm of antibody 10G4, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-05-19
Release date:2023-05-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.368 Å)
Cite:Neutralization of CoV-2 omicron sublineages by affinity-matured class 5 antibodies
To Be Published
8CWJ
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BU of 8cwj by Molmil
Fab arms of antibodies 4C12-B12 and CR3022 bound to pangolin receptor binding domain (pRBD)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2022-05-19
Release date:2023-05-24
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.449 Å)
Cite:Neutralization of CoV-2 omicron lineages by affinity-matured class 5 antibodies
To Be Published
1DUV
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BU of 1duv by Molmil
CRYSTAL STRUCTURE OF E. COLI ORNITHINE TRANSCARBAMOYLASE COMPLEXED WITH NDELTA-L-ORNITHINE-DIAMINOPHOSPHINYL-N-SULPHONIC ACID (PSORN)
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, NDELTA-(N'-SULPHODIAMINOPHOSPHINYL)-L-ORNITHINE, ORNITHINE TRANSCARBAMOYLASE
Authors:Langley, D.B, Templeton, M.D, Fields, B.A, Mitchell, R.E, Collyer, C.A.
Deposit date:2000-01-18
Release date:2000-07-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mechanism of inactivation of ornithine transcarbamoylase by Ndelta -(N'-Sulfodiaminophosphinyl)-L-ornithine, a true transition state analogue? Crystal structure and implications for catalytic mechanism.
J.Biol.Chem., 275, 2000
6D9I
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BU of 6d9i by Molmil
Pekin duck egg lysozyme isoform II (DEL-II)
Descriptor: CHLORIDE ION, Lysozyme, MAGNESIUM ION
Authors:Langley, D.B, Christ, D.
Deposit date:2018-04-30
Release date:2018-09-05
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:Crystal structure of duck egg lysozyme isoform II (DEL-II).
BMC Struct. Biol., 18, 2018
5V94
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BU of 5v94 by Molmil
Pekin duck egg lysozyme isoform III (DEL-III), cubic form
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, ...
Authors:Langley, D.B, Christ, D.
Deposit date:2017-03-22
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
5V92
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BU of 5v92 by Molmil
Pekin duck egg lysozyme isoform III (DEL-III), orthorhombic form
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PHOSPHATE ION, lysozyme isoform III
Authors:Langley, D.B, Christ, D.
Deposit date:2017-03-22
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.11 Å)
Cite:Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
5V8G
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BU of 5v8g by Molmil
Pekin duck lysozyme isoform I (DEL-I)
Descriptor: CHLORIDE ION, THIOCYANATE ION, lysozyme isoform I
Authors:Langley, D.B, Christ, D.
Deposit date:2017-03-22
Release date:2017-11-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Structural basis of antigen recognition: crystal structure of duck egg lysozyme.
Acta Crystallogr D Struct Biol, 73, 2017
2CFD
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BU of 2cfd by Molmil
AGAO in complex with wc4l3 (Ru-wire inhibitor, 4-carbon linker, lambda enantiomer, data set 3)
Descriptor: BIS[1H,1'H-2,2'-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1'~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM, COPPER (II) ION, GLYCEROL, ...
Authors:Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
Deposit date:2006-02-20
Release date:2007-05-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Enantiomer-Specific Binding of Ruthenium(II) Molecular Wires by the Amine Oxidase of Arthrobacter Globiformis.
J.Am.Chem.Soc., 130, 2008
2CFL
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BU of 2cfl by Molmil
AGAO in complex with wc6b (Ru-wire inhibitor, 6-carbon linker, data set b)
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
Deposit date:2006-02-22
Release date:2007-05-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enantiomer-Specific Binding of Ruthenium(II) Molecular Wires by the Amine Oxidase of Arthrobacter Globiformis.
J.Am.Chem.Soc., 130, 2008
2CFK
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BU of 2cfk by Molmil
AGAO in complex with wc5 (Ru-wire inhibitor, 5-carbon linker)
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
Deposit date:2006-02-21
Release date:2007-05-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis.
J. Am. Chem. Soc., 130, 2008
2CG1
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BU of 2cg1 by Molmil
AGAO in complex with wc11b (Ru-wire inhibitor, 11-carbon linker, data set b)
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
Deposit date:2006-02-27
Release date:2007-05-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Enantiomer-Specific Binding of Ruthenium(II) Molecular Wires by the Amine Oxidase of Arthrobacter Globiformis.
J.Am.Chem.Soc., 130, 2008
2CFW
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BU of 2cfw by Molmil
AGAO in complex with wc7a (Ru-wire inhibitor, 7-carbon linker, data set a)
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
Deposit date:2006-02-24
Release date:2007-05-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Enantiomer-Specific Binding of Ruthenium(II) Molecular Wires by the Amine Oxidase of Arthrobacter Globiformis.
J.Am.Chem.Soc., 130, 2008
2CFG
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BU of 2cfg by Molmil
AGAO in complex with wc4d3 (Ru-wire inhibitor, 4-carbon linker, delta enantiomer, data set 3)
Descriptor: BIS[1H,1'H-2,2'-BIPYRIDINATO(2-)-KAPPA~2~N~1~,N~1'~]{3-[4-(1,10-DIHYDRO-1,10-PHENANTHROLIN-4-YL-KAPPA~2~N~1~,N~10~)BUTOXY]-N,N-DIMETHYLANILINATO(2-)}RUTHENIUM, COPPER (II) ION, GLYCEROL, ...
Authors:Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
Deposit date:2006-02-21
Release date:2007-05-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Enantiomer-Specific Binding of Ruthenium(II) Molecular Wires by the Amine Oxidase of Arthrobacter Globiformis.
J.Am.Chem.Soc., 130, 2008
2CG0
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BU of 2cg0 by Molmil
AGAO in complex with wc9a (Ru-wire inhibitor, 9-carbon linker, data set a)
Descriptor: COPPER (II) ION, GLYCEROL, PHENYLETHYLAMINE OXIDASE, ...
Authors:Langley, D.B, Duff, A.P, Freeman, H.C, Guss, J.M, Juda, G.A, Dooley, D.M, Contakes, S.M, Halpern-Manners, N.W, Dunn, A.R, Gray, H.B.
Deposit date:2006-02-27
Release date:2007-05-01
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Enantiomer-Specific Binding of Ruthenium(II) Molecular Wires by the Amine Oxidase of Arthrobacter Globiformis.
J.Am.Chem.Soc., 130, 2008
2EPL
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BU of 2epl by Molmil
N-acetyl-B-D-glucosaminidase (GCNA) from Streptococcus gordonii
Descriptor: GLYCEROL, N-acetyl-beta-D-glucosaminidase, SULFATE ION
Authors:Langley, D.B, Harty, D.W.S, Guss, J.M, Collyer, C.A.
Deposit date:2007-03-30
Release date:2008-03-11
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline
J.Mol.Biol., 377, 2008

 

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