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4PVS
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BU of 4pvs by Molmil
Crystal structure of fully-cleaved human l-asparaginase protein in complex with l-aspartate
Descriptor: ASPARTIC ACID, Isoaspartyl peptidase/L-asparaginase, SODIUM ION
Authors:Nomme, J, Lavie, A.
Deposit date:2014-03-18
Release date:2014-03-26
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Structures of apo and product-bound human L-asparaginase: insights into the mechanism of autoproteolysis and substrate hydrolysis.
Biochemistry, 51, 2012
4PVQ
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BU of 4pvq by Molmil
Crystal structure of sulfate-bound human l-asparaginase protein
Descriptor: IODIDE ION, Isoaspartyl peptidase/L-asparaginase, SODIUM ION, ...
Authors:Nomme, J, Lavie, A.
Deposit date:2014-03-18
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structures of apo and product-bound human L-asparaginase: insights into the mechanism of autoproteolysis and substrate hydrolysis.
Biochemistry, 51, 2012
4PVP
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BU of 4pvp by Molmil
Crystal structure of malonate-bound human L-asparaginase protein
Descriptor: Isoaspartyl peptidase/L-asparaginase, MALONATE ION, SODIUM ION
Authors:Nomme, J, Lavie, A.
Deposit date:2014-03-18
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of apo and product-bound human L-asparaginase: insights into the mechanism of autoproteolysis and substrate hydrolysis.
Biochemistry, 51, 2012
4TMK
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BU of 4tmk by Molmil
COMPLEX OF E. COLI THYMIDYLATE KINASE WITH THE BISUBSTRATE INHIBITOR TP5A
Descriptor: P1-(5'-ADENOSYL)P5-(5'-THYMIDYL)PENTAPHOSPHATE, PROTEIN (THYMIDYLATE KINASE)
Authors:Lavie, A, Ostermann, N, Schlichting, I.
Deposit date:1998-08-31
Release date:1998-11-25
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase.
Proc.Natl.Acad.Sci.USA, 95, 1998
2NO9
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BU of 2no9 by Molmil
The structure of deoxycytidine kinase complexed with troxacitabine and ADP.
Descriptor: 4-AMINO-1-[(2S,4S)-2-(HYDROXYMETHYL)-1,3-DIOXOLAN-4-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
Authors:Sabini, E, Lavie, A.
Deposit date:2006-10-25
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase.
Nucleic Acids Res., 35, 2007
2NOA
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BU of 2noa by Molmil
The structure of deoxycytidine kinase complexed with lamivudine and ADP.
Descriptor: 4-AMINO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase
Authors:Sabini, E, Lavie, A.
Deposit date:2006-10-25
Release date:2007-02-13
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase.
Nucleic Acids Res., 35, 2007
2OFX
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BU of 2ofx by Molmil
crystal structure of the APSK domain of human PAPSS1 in complex with ADPMg and PAPS
Descriptor: 3'-PHOSPHATE-ADENOSINE-5'-PHOSPHATE SULFATE, ADENOSINE-5'-DIPHOSPHATE, Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1, ...
Authors:Sekulic, N, Lavie, A.
Deposit date:2007-01-04
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Elucidation of the Active Conformation of the APS-Kinase Domain of Human PAPS Synthetase 1.
J.Mol.Biol., 367, 2007
2OFW
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BU of 2ofw by Molmil
Crystal structure of the APSK domain of human PAPSS1 complexed with 2 APS molecules
Descriptor: ADENOSINE-5'-PHOSPHOSULFATE, APS kinase domain of the PAPS synthetase 1, MAGNESIUM ION
Authors:Sekulic, N, Lavie, A.
Deposit date:2007-01-04
Release date:2007-04-10
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Elucidation of the Active Conformation of the APS-Kinase Domain of Human PAPS Synthetase 1.
J.Mol.Biol., 367, 2007
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