6ODD
| Crystal structure of the human complex ACP-ISD11 | Descriptor: | Acyl carrier protein, mitochondrial, CALCIUM ION, ... | Authors: | Herrera, M.G, Noguera, M.E, Klinke, S, Santos, J. | Deposit date: | 2019-03-26 | Release date: | 2019-11-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the Human ACP-ISD11 Heterodimer. Biochemistry, 58, 2019
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2Q76
| Mouse anti-hen egg white lysozyme antibody F10.6.6 Fab fragment | Descriptor: | Fab F10.6.6 fragment Heavy Chain, Fab F10.6.6 fragment Light Chain | Authors: | Cauerhff, A, Klinke, S, Acierno, J.P, Goldbaum, F.A, Braden, B.C. | Deposit date: | 2007-06-06 | Release date: | 2008-03-18 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Affinity maturation increases the stability and plasticity of the Fv domain of anti-protein antibodies. J.Mol.Biol., 374, 2007
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2QT7
| Crystallographic structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2 at 1.30 Angstroms | Descriptor: | CALCIUM ION, Receptor-type tyrosine-protein phosphatase-like N | Authors: | Primo, M.E, Klinke, S, Sica, M.P, Goldbaum, F.A, Jakoncic, J, Poskus, E, Ermacora, M.R. | Deposit date: | 2007-08-01 | Release date: | 2007-12-11 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Structure of the Mature Ectodomain of the Human Receptor-type Protein-tyrosine Phosphatase IA-2 J.Biol.Chem., 283, 2008
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6BN3
| CTX-M-151 class A extended-spectrum beta-lactamase apo crystal structure at 1.3 Angstrom resolution | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase | Authors: | Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S. | Deposit date: | 2017-11-16 | Release date: | 2018-11-21 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.278 Å) | Cite: | Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam. Antimicrob.Agents Chemother., 65, 2021
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6BPF
| CTX-M-151 class A extended-spectrum beta-lactamase crystal structure in complex with avibactam at 1.32 Angstrom resolution | Descriptor: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase | Authors: | Power, P, Ghiglione, B, Rodriguez, M.M, Gutkind, G, Ishii, Y, Bonomo, R.A, Klinke, S. | Deposit date: | 2017-11-23 | Release date: | 2018-11-28 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.318 Å) | Cite: | Structural and Biochemical Characterization of the Novel CTX-M-151 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactam. Antimicrob.Agents Chemother., 65, 2021
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6BNX
| Crystal structure of V278E-glyoxalase I mutant from Zea mays in space group P6(3) | Descriptor: | COBALT (II) ION, Lactoylglutathione lyase | Authors: | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | Deposit date: | 2017-11-17 | Release date: | 2018-11-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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6BNZ
| Crystal structure of E144Q-glyoxalase I mutant from Zea mays in space group P4(1)2(1)2 | Descriptor: | COBALT (II) ION, FORMIC ACID, GLUTATHIONE, ... | Authors: | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | Deposit date: | 2017-11-17 | Release date: | 2018-11-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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6BNN
| Crystal structure of V278E-glyoxalase I mutant from Zea mays in space group P4(1)2(1)2 | Descriptor: | COBALT (II) ION, FORMIC ACID, GLUTATHIONE, ... | Authors: | Alvarez, C.E, Agostini, R.B, Gonzalez, J.M, Drincovich, M.F, Campos Bermudez, V.A, Klinke, S. | Deposit date: | 2017-11-17 | Release date: | 2018-11-21 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Deciphering the number and location of active sites in the monomeric glyoxalase I of Zea mays. Febs J., 286, 2019
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7TBR
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4D6Y
| Crystal structure of the receiver domain of NtrX from Brucella abortus in complex with beryllofluoride and magnesium | Descriptor: | BACTERIAL REGULATORY, FIS FAMILY PROTEIN, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Otero, L.H, Fernandez, I, Carrica, M.C, Klinke, S, Goldbaum, F.A. | Deposit date: | 2014-11-18 | Release date: | 2015-07-08 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Snapshots of Conformational Changes Shed Light Into the Ntrx Receiver Domain Signal Transduction Mechanism J.Mol.Biol., 427, 2015
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4E0F
| Crystallographic structure of trimeric Riboflavin Synthase from Brucella abortus in complex with riboflavin | Descriptor: | RIBOFLAVIN, Riboflavin synthase subunit alpha | Authors: | Serer, M.I, Bonomi, H.R, Guimaraes, B.G, Rossi, R.C, Goldbaum, F.A, Klinke, S. | Deposit date: | 2012-03-03 | Release date: | 2013-10-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility. Acta Crystallogr.,Sect.D, 70, 2014
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4FXU
| Crystallographic structure of trimeric riboflavin synthase from Brucella abortus | Descriptor: | Riboflavin synthase subunit alpha | Authors: | Serer, M.I, Bonomi, H.R, Guimaraes, B.G, Rossi, R.C, Goldbaum, F.A, Klinke, S. | Deposit date: | 2012-07-03 | Release date: | 2014-03-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility. Acta Crystallogr.,Sect.D, 70, 2014
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4G6I
| Crystallographic structure of trimeric riboflavin synthase from Brucella abortus in complex with roseoflavin | Descriptor: | 1-deoxy-1-[8-(dimethylamino)-7-methyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl]-D-ribitol, Riboflavin synthase subunit alpha | Authors: | Serer, M.I, Bonomi, H.R, Guimaraes, B.G, Rossi, R.C, Goldbaum, F.A, Klinke, S. | Deposit date: | 2012-07-19 | Release date: | 2014-03-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility. Acta Crystallogr.,Sect.D, 70, 2014
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4GQN
| Crystallographic structure of trimeric Riboflavin Synthase from Brucella abortus in complex with 5-Nitro-6-(D-Ribitylamino)-2,4(1H,3H) Pyrimidinedione | Descriptor: | 5-NITRO-6-RIBITYL-AMINO-2,4(1H,3H)-PYRIMIDINEDIONE, Riboflavin synthase subunit alpha | Authors: | Serer, M.I, Bonomi, H.R, Guimaraes, B.G, Rossi, R.C, Goldbaum, F.A, Klinke, S. | Deposit date: | 2012-08-23 | Release date: | 2014-03-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystallographic and kinetic study of riboflavin synthase from Brucella abortus, a chemotherapeutic target with an enhanced intrinsic flexibility. Acta Crystallogr.,Sect.D, 70, 2014
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6CAC
| Crystal structure of NDM-1 metallo-beta-lactamase harboring an insertion of a Pro residue in L3 loop | Descriptor: | CADMIUM ION, CALCIUM ION, COBALT (II) ION, ... | Authors: | Alzari, P.M, Giannini, E, Palacios, A, Mojica, M, Bonomo, R, Llarrull, L, Vila, A. | Deposit date: | 2018-01-30 | Release date: | 2018-10-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | The Reaction Mechanism of Metallo-beta-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop. Antimicrob. Agents Chemother., 63, 2019
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7R63
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3N4W
| Crystal structure of an abridged SER to ALA mutant of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase ICA512/IA-2 at pH 7.5 | Descriptor: | CALCIUM ION, Receptor-type tyrosine-protein phosphatase-like N | Authors: | Primo, M.E, Jakoncic, J, Poskus, E, Ermacora, M.R. | Deposit date: | 2010-05-23 | Release date: | 2010-12-01 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2. J.Biol.Chem., 283, 2008
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3NG8
| Crystal structure of an abridged SER TO ALA MUTANT OF THE MATURE ECTODOMAIN of the human receptor-type protein-tyrosine phosphatase ICA512/IA-2 at PH 8.5 | Descriptor: | CALCIUM ION, Receptor-type tyrosine-protein phosphatase-like N | Authors: | Primo, M.E, Jakoncic, J, Poskus, E, Ermacora, M.R. | Deposit date: | 2010-06-11 | Release date: | 2010-12-15 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Structure of the mature ectodomain of the human receptor-type protein-tyrosine phosphatase IA-2. J.Biol.Chem., 283, 2008
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2MPB
| NMR structure of BA42 protein from the psychrophilic bacteria Bizionia argentinensis sp. nov | Descriptor: | BA42 | Authors: | Cicero, D, Aran, M, Smal, C, Pellizza, L, Gallo, M. | Deposit date: | 2014-05-14 | Release date: | 2014-08-20 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand-alone TPM domain. Proteins, 82, 2014
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8STL
| Crystal Structure of Nanobody PIK3_Nb16 against wild-type PI3Kalpha | Descriptor: | Nanobody PIK3_Nb16, SULFATE ION | Authors: | Nwafor, J.N, Srinivasan, L, Chen, Z, Gabelli, S.B, Iheanacho, A, Alzogaray, V, Klinke, S. | Deposit date: | 2023-05-10 | Release date: | 2024-05-22 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Development of isoform specific nanobodies for Class I PI3Ks To be published
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4D50
| Structure of human deoxyhypusine hydroxylase | Descriptor: | DEOXYHYPUSINE HYDROXYLASE, FE (III) ION, GUANIDINE, ... | Authors: | Han, Z, Sakai, N, Hilgenfeld, R. | Deposit date: | 2014-10-31 | Release date: | 2015-04-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the Peroxo-Diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination. Structure, 23, 2015
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4D4Z
| STRUCTURE OF HUMAN DEOXYHYPUSINE HYDROXYLASE in complex with glycerol | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DEOXYHYPUSINE HYDROXYLASE, FE (III) ION, ... | Authors: | Han, Z, Sakai, N, Hilgenfeld, R. | Deposit date: | 2014-10-31 | Release date: | 2015-04-15 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structure of the Peroxo-Diiron(III) Intermediate of Deoxyhypusine Hydroxylase, an Oxygenase Involved in Hypusination. Structure, 23, 2015
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3N01
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3NP5
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