1F21
 
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1WUD
 | | E. coli RecQ HRDC domain | | Descriptor: | ATP-dependent DNA helicase recQ | | Authors: | Bernstein, D.A, Keck, J.L. | | Deposit date: | 2004-12-04 | | Release date: | 2005-08-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Conferring Substrate Specificity to DNA Helicases: Role of the RecQ HRDC Domain
STRUCTURE, 13, 2005
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1YO8
 | | Structure of the C-terminal domain of human thrombospondin-2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Carlson, C.B, Bernstein, D.A, Annis, D.S, Misenheimer, T.M, Hannah, B.A, Mosher, D.F, Keck, J.L. | | Deposit date: | 2005-01-26 | | Release date: | 2005-09-27 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the calcium-rich signature domain of human thrombospondin-2
Nat.Struct.Mol.Biol., 12, 2005
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6D9Q
 | | The sulfate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | | Descriptor: | GLYCEROL, Hypoxanthine phosphoribosyltransferase, SULFATE ION | | Authors: | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | | Deposit date: | 2018-04-30 | | Release date: | 2019-05-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.056 Å) | | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.
Elife, 8, 2019
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6DCR
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6DGD
 | | PriA helicase bound to dsDNA of a DNA replication fork | | Descriptor: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | | Authors: | Satyshur, K.A, Windgassen, T.A, Keck, J.L. | | Deposit date: | 2018-05-17 | | Release date: | 2018-09-05 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.823 Å) | | Cite: | Structure-specific DNA replication-fork recognition directs helicase and replication restart activities of the PriA helicase.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6D9R
 | | The substrate-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | | Descriptor: | 1,2-ETHANEDIOL, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, 9-DEAZAGUANINE, ... | | Authors: | Satyshur, K.A, Wolak, C, Anderson, B, Dubiel, K, Keck, J.L. | | Deposit date: | 2018-04-30 | | Release date: | 2019-05-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (1.64 Å) | | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.
Elife, 8, 2019
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6D9S
 | | The (p)ppGpp-bound crystal structure of HPRT (hypoxanthine phosphoribosyltransferase) | | Descriptor: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5',3'-TETRAPHOSPHATE, Hypoxanthine phosphoribosyltransferase, ... | | Authors: | Satyshur, K.A, Dubiel, K, Anderson, B, Wolak, C, Keck, J.L. | | Deposit date: | 2018-04-30 | | Release date: | 2019-05-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.105 Å) | | Cite: | Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction.
Elife, 8, 2019
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3MXN
 | | Crystal structure of the RMI core complex | | Descriptor: | BENZAMIDINE, RecQ-mediated genome instability protein 1, RecQ-mediated genome instability protein 2 | | Authors: | Hoadley, K.A, Xu, D, Xue, Y, Satyshur, K.A, Wang, W, Keck, J.L. | | Deposit date: | 2010-05-07 | | Release date: | 2010-09-15 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structure and cellular roles of the RMI core complex from the bloom syndrome dissolvasome.
Structure, 18, 2010
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3NCT
 | | X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of reca | | Descriptor: | Protein psiB | | Authors: | Petrova, V, Satyshur, K.A, George, N.P, McCaslin, D, Cox, M.M, Keck, J.L. | | Deposit date: | 2010-06-05 | | Release date: | 2010-07-21 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | X-ray crystal structure of the bacterial conjugation factor PsiB, a negative regulator of RecA.
J.Biol.Chem., 285, 2010
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3PVS
 | | Structure and biochemical activities of Escherichia coli MgsA | | Descriptor: | PHOSPHATE ION, Replication-associated recombination protein A | | Authors: | Page, A.N, George, N.P, Marceau, A.H, Cox, M.M, Keck, J.L. | | Deposit date: | 2010-12-07 | | Release date: | 2011-02-02 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structure and Biochemical Activities of Escherichia coli MgsA.
J.Biol.Chem., 286, 2011
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3SXU
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3UFM
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3UDG
 | | Structure of Deinococcus radiodurans SSB bound to ssDNA | | Descriptor: | 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', Single-stranded DNA-binding protein, THYMIDINE-5'-PHOSPHATE | | Authors: | George, N.P, Ngo, K.V, Chitteni-Patu, S, Norais, C.A, Battista, J.R, Cox, M.M, Keck, J.L. | | Deposit date: | 2011-10-28 | | Release date: | 2012-05-16 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure and Cellular Dynamics of Deinococcus radiodurans Single-stranded DNA (ssDNA)-binding Protein (SSB)-DNA Complexes.
J.Biol.Chem., 287, 2012
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3UF7
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3VDY
 | | B. subtilis SsbB/ssDNA | | Descriptor: | 5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3', Single-stranded DNA-binding protein ssbB | | Authors: | Yadav, T, Carrasco, B, Myers, A.R, George, N.P, Keck, J.L, Alonso, J.C. | | Deposit date: | 2012-01-06 | | Release date: | 2012-03-14 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Genetic recombination in Bacillus subtilis: a division of labor between two single-strand DNA-binding proteins.
Nucleic Acids Res., 40, 2012
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3V8E
 | | Crystal structure of the yeast nicotinamidase Pnc1p bound to the inhibitor nicotinaldehyde | | Descriptor: | MAGNESIUM ION, Nicotinamidase, ZINC ION | | Authors: | Hoadley, K.A, Smith, B.C, Denu, J.M, Keck, J.L. | | Deposit date: | 2011-12-22 | | Release date: | 2012-01-25 | | Method: | X-RAY DIFFRACTION (2.71 Å) | | Cite: | Structural and Kinetic Isotope Effect Studies of Nicotinamidase (Pnc1) from Saccharomyces cerevisiae.
Biochemistry, 51, 2012
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6W1I
 | | Re-interpretation of ppGpp (G4P) electron density in the deposited crystal structure of Xanthine phosphoribosyltransferase (XPRT) (1Y0B). | | Descriptor: | GUANOSINE-5',3'-TETRAPHOSPHATE, SODIUM ION, Xanthine phosphoribosyltransferase | | Authors: | Satyshur, K.A, Anderson, B.W, Keck, J.L, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2020-03-04 | | Release date: | 2020-07-29 | | Last modified: | 2021-04-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Molecular Mechanism of Regulation of the Purine Salvage Enzyme XPRT by the Alarmones pppGpp, ppGpp, and pGpp.
J.Mol.Biol., 432, 2020
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2PNH
 | | Escherichia coli PriB E39A variant | | Descriptor: | Primosomal replication protein n | | Authors: | Lopper, M.E, Keck, J.L. | | Deposit date: | 2007-04-24 | | Release date: | 2007-08-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | A hand-off mechanism for primosome assembly in replication restart.
Mol.Cell, 26, 2007
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2RHP
 | | The Thrombospondin-1 Polymorphism Asn700Ser Associated with Cornoary Artery Disease Causes Local and Long-Ranging Changes in Protein Structure | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Carlson, C.B, Keck, J.L, Mosher, D.F. | | Deposit date: | 2007-10-09 | | Release date: | 2008-05-27 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Influences of the N700S Thrombospondin-1 Polymorphism on Protein Structure and Stability.
J.Biol.Chem., 283, 2008
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3C9D
 | | Crystal structure of Vps75 | | Descriptor: | Vacuolar protein sorting-associated protein 75 | | Authors: | Berndsen, C.E, Tsubota, T, Lindner, S.E, Lee, S, Holton, J.M, Kaufman, P.D, Keck, J.L, Denu, J.M. | | Deposit date: | 2008-02-15 | | Release date: | 2008-08-12 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular functions of the histone acetyltransferase chaperone complex Rtt109-Vps75
Nat.Struct.Mol.Biol., 15, 2008
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3C94
 | | ExoI/SSB-Ct complex | | Descriptor: | Exodeoxyribonuclease I, MAGNESIUM ION, Single-stranded DNA-binding C-terminal tail peptide | | Authors: | Lu, D, Keck, J.L. | | Deposit date: | 2008-02-15 | | Release date: | 2008-07-08 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis of Escherichia coli single-stranded DNA-binding protein stimulation of exonuclease I.
Proc.Natl.Acad.Sci.USA, 105, 2008
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4NL4
 | | PriA Helicase Bound to ADP | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Primosome assembly protein PriA, ZINC ION | | Authors: | Bhattacharyya, B, George, N.P, Keck, J.L. | | Deposit date: | 2013-11-13 | | Release date: | 2014-01-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | Structural mechanisms of PriA-mediated DNA replication restart.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4NL8
 | | PriA Helicase Bound to SSB C-terminal Tail Peptide | | Descriptor: | Primosome assembly protein PriA, Single-stranded DNA-binding protein, ZINC ION | | Authors: | Bhattacharyya, B, George, N.P, Thurmes, T.M, Keck, J.L. | | Deposit date: | 2013-11-13 | | Release date: | 2014-01-08 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.08 Å) | | Cite: | Structural mechanisms of PriA-mediated DNA replication restart.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4H5B
 | | Crystal Structure of DR_1245 from Deinococcus radiodurans | | Descriptor: | BROMIDE ION, DR_1245 protein, GLYCEROL, ... | | Authors: | Norais, C, Servant, P, Bouthier-de-la-Tour, C, Coureux, P.D, Ithurbide, S, Vannier, F, Guerin, P, Dulberger, C.L, Satyshur, K.A, Keck, J.L, Armengaud, J, Cox, M.M, Sommer, S. | | Deposit date: | 2012-09-18 | | Release date: | 2013-01-30 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The Deinococcus radiodurans DR1245 Protein, a DdrB Partner Homologous to YbjN Proteins and Reminiscent of Type III Secretion System Chaperones.
Plos One, 8, 2013
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