2PHE
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![BU of 2phe by Molmil](/molmil-images/mine/2phe) | Model for VP16 binding to PC4 | Descriptor: | Alpha trans-inducing protein, TRANSCRIPTIONAL COACTIVATOR PC4 | Authors: | Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R. | Deposit date: | 2007-04-11 | Release date: | 2007-04-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Properties of the Promiscuous VP16 Activation Domain Biochemistry, 44, 2005
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2PHG
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![BU of 2phg by Molmil](/molmil-images/mine/2phg) | Model for VP16 binding to TFIIB | Descriptor: | Alpha trans-inducing protein, Transcription initiation factor IIB | Authors: | Jonker, H.R.A, Wechselberger, R.W, Boelens, R, Folkers, G.E, Kaptein, R. | Deposit date: | 2007-04-11 | Release date: | 2007-04-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Properties of the Promiscuous VP16 Activation Domain Biochemistry, 44, 2005
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2JQ7
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![BU of 2jq7 by Molmil](/molmil-images/mine/2jq7) | Model for thiostrepton binding to the ribosomal L11-RNA | Descriptor: | 50S RIBOSOMAL PROTEIN L11, RIBOSOMAL RNA, THIOSTREPTON | Authors: | Jonker, H.R.A, Ilin, S, Grimm, S.K, Woehnert, J, Schwalbe, H. | Deposit date: | 2007-05-30 | Release date: | 2007-07-03 | Last modified: | 2021-08-18 | Method: | SOLUTION NMR | Cite: | L11 Domain Rearrangement Upon Binding to RNA and Thiostrepton Studied by NMR Spectroscopy Nucleic Acids Res., 35, 2007
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2K3F
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![BU of 2k3f by Molmil](/molmil-images/mine/2k3f) | |
5GQS
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![BU of 5gqs by Molmil](/molmil-images/mine/5gqs) | NMR based solution structure of PTS system, galactitol-specific IIB component from methicillin resistant Staphylococcus aureus | Descriptor: | PTS galactitol transporter subunit IIB | Authors: | Wahab, A, Schwalbe, H, Shahid, M.F, Richter, C, Jonker, H.R.A. | Deposit date: | 2016-08-08 | Release date: | 2016-09-14 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | NMR based solution structure of PTS system, galactitol-specific IIB component from methicillin resistant Staphylococcus aureus To Be Published
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2W0G
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![BU of 2w0g by Molmil](/molmil-images/mine/2w0g) | |
6Q2Z
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![BU of 6q2z by Molmil](/molmil-images/mine/6q2z) | NMR solution structure of the HVO_2922 protein from Haloferax volcanii | Descriptor: | UPF0339 family protein | Authors: | Kubatova, N, Jonker, H.R.A, Saxena, K, Richter, C, Marchfelder, A, Schwalbe, H. | Deposit date: | 2018-12-03 | Release date: | 2019-06-12 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution Structure and Dynamics of the Small Protein HVO_2922 from Haloferax volcanii. Chembiochem, 21, 2020
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7A05
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![BU of 7a05 by Molmil](/molmil-images/mine/7a05) | NMR structure of D3-D4 domains of Vibrio vulnificus ribosomal protein S1 | Descriptor: | 30S ribosomal protein S1 | Authors: | Qureshi, N.S, Matzel, T, Cetiner, E.C, Schnieders, S, Jonker, H.R.A, Schwalbe, H, Fuertig, B. | Deposit date: | 2020-08-06 | Release date: | 2021-06-23 | Last modified: | 2024-01-17 | Method: | SOLUTION NMR | Cite: | NMR structure of the Vibrio vulnificus ribosomal protein S1 domains D3 and D4 provides insights into molecular recognition of single-stranded RNAs. Nucleic Acids Res., 49, 2021
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8CLR
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![BU of 8clr by Molmil](/molmil-images/mine/8clr) | Integrated NMR/MD structure determination of a dynamic and thermodynamically stable CUUG RNA tetraloop | Descriptor: | RNA hairpin with CUUG tetraloop | Authors: | Oxenfarth, A, Kuemmerer, F, Bottaro, S, Schnieders, R, Pinter, G, Jonker, H.R.A, Fuertig, B, Richter, C, Blackledge, M, Lindorff-Larsen, K, Schwalbe, H. | Deposit date: | 2023-02-17 | Release date: | 2023-07-19 | Last modified: | 2023-08-09 | Method: | SOLUTION NMR | Cite: | Integrated NMR/Molecular Dynamics Determination of the Ensemble Conformation of a Thermodynamically Stable CUUG RNA Tetraloop. J.Am.Chem.Soc., 145, 2023
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6F2X
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![BU of 6f2x by Molmil](/molmil-images/mine/6f2x) | Structural characterization of the Mycobacterium tuberculosis Protein Tyrosine Kinase A (PtkA) | Descriptor: | Protein Tyrosine Kinase A | Authors: | Niesteruk, A, Jonker, H.R.A, Sreeramulu, S, Richter, C, Hutchison, M, Linhard, V, Schwalbe, H. | Deposit date: | 2017-11-27 | Release date: | 2018-07-04 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The domain architecture of PtkA, the first tyrosine kinase fromMycobacterium tuberculosis, differs from the conventional kinase architecture. J. Biol. Chem., 293, 2018
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5MVB
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![BU of 5mvb by Molmil](/molmil-images/mine/5mvb) | Solution structure of a human G-Quadruplex hybrid-2 form in complex with a Gold-ligand. | Descriptor: | DNA (26-MER), POTASSIUM ION, bis(m2-Oxo)-bis(2-methyl-2,2'-bipyridine)-di-gold(iii) | Authors: | Wirmer-Bartoschek, J, Jonker, H.R.A, Bendel, L.E, Gruen, T, Bazzicalupi, C, Messori, L, Gratteri, P, Schwalbe, H. | Deposit date: | 2017-01-16 | Release date: | 2017-05-31 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of a Ligand/Hybrid-2-G-Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding. Angew. Chem. Int. Ed. Engl., 56, 2017
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5N5C
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![BU of 5n5c by Molmil](/molmil-images/mine/5n5c) | NMR solution structure of the TSL2 RNA hairpin | Descriptor: | RNA (19-MER) | Authors: | Garcia-Lopez, A, Wacker, A, Tessaro, F, Jonker, H.R.A, Richter, C, Comte, A, Berntenis, N, Schmucki, R, Hatje, K, Sciarra, D, Konieczny, P, Fournet, G, Faustino, I, Orozco, M, Artero, R, Goekjian, P, Metzger, F, Ebeling, M, Joseph, B, Schwalbe, H, Scapozza, L. | Deposit date: | 2017-02-13 | Release date: | 2018-03-14 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes. Nat Commun, 9, 2018
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6F27
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![BU of 6f27 by Molmil](/molmil-images/mine/6f27) | NMR solution structure of non-bound [des-Arg10]-kallidin (DAKD) | Descriptor: | DAKD | Authors: | Richter, C, Jonker, H.R.A, Schwalbe, H, Joedicke, L, Mao, J, Kuenze, G, Reinhart, C, Kalavacherla, T, Meiler, J, Preu, J, Michel, H, Glaubitz, C. | Deposit date: | 2017-11-23 | Release date: | 2018-01-10 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nat. Chem. Biol., 14, 2018
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2KOC
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![BU of 2koc by Molmil](/molmil-images/mine/2koc) | NMR solution structure of a 14-mer hairpin RNA with cUUCGg tetraloop | Descriptor: | RNA (5'-R(P*GP*GP*CP*AP*CP*UP*UP*CP*GP*GP*UP*GP*CP*C)-3') | Authors: | Nozinovic, S, Fuertig, B, Jonker, H.R.A, Richter, C, Schwalbe, H. | Deposit date: | 2009-09-17 | Release date: | 2009-12-01 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | High-resolution NMR structure of an RNA model system: the 14-mer cUUCGg tetraloop hairpin RNA Nucleic Acids Res., 2009
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2KER
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![BU of 2ker by Molmil](/molmil-images/mine/2ker) | alpha-amylase inhibitor Parvulustat (Z-2685) from Streptomyces parvulus | Descriptor: | Alpha-amylase inhibitor Z-2685 | Authors: | Rehm, S, Han, S, Hassani, I, Sokocevic, A, Jonker, H.R.A, Engels, J.W, Schwalbe, H. | Deposit date: | 2009-02-02 | Release date: | 2009-02-17 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | The high resolution NMR structure of parvulustat (Z-2685) from Streptomyces parvulus FH-1641: comparison with tendamistat from Streptomyces tendae 4158 Chembiochem, 10, 2009
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2K5B
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![BU of 2k5b by Molmil](/molmil-images/mine/2k5b) | Human CDC37-HSP90 docking model based on NMR | Descriptor: | Heat shock protein HSP 90-alpha, Hsp90 co-chaperone Cdc37 | Authors: | Sreeramulu, S, Jonker, H.R.A, Lancaster, C.R, Richter, C, Langer, T, Schwalbe, H. | Deposit date: | 2008-06-26 | Release date: | 2008-12-09 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The human Cdc37.Hsp90 complex studied by heteronuclear NMR spectroscopy J.Biol.Chem., 284, 2009
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2KMJ
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![BU of 2kmj by Molmil](/molmil-images/mine/2kmj) | High resolution NMR solution structure of a complex of HIV-2 TAR RNA and a synthetic tripeptide in a 1:2 stoichiometry | Descriptor: | Pyrimidinylpeptide, RNA (28-MER) | Authors: | Ferner, J, Suhartono, M, Breitung, S, Jonker, H.R.A, Hennig, M, Woehnert, J, Goebel, M, Schwalbe, H. | Deposit date: | 2009-07-30 | Release date: | 2009-08-18 | Last modified: | 2023-11-15 | Method: | SOLUTION NMR | Cite: | Structures of HIV TAR RNA-ligand complexes reveal higher binding stoichiometries. Chembiochem, 10, 2009
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2L2X
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![BU of 2l2x by Molmil](/molmil-images/mine/2l2x) | Thiostrepton, oxidized at CA-CB bond of residue 9 | Descriptor: | Thiostrepton | Authors: | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2013-06-26 | Method: | SOLUTION NMR | Cite: | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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2L2Z
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![BU of 2l2z by Molmil](/molmil-images/mine/2l2z) | Thiostrepton, reduced at N-CA bond of residue 14 | Descriptor: | Thiostrepton | Authors: | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2013-06-26 | Method: | SOLUTION NMR | Cite: | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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2L2W
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![BU of 2l2w by Molmil](/molmil-images/mine/2l2w) | Thiostrepton | Descriptor: | Thiostrepton | Authors: | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2013-05-08 | Method: | SOLUTION NMR | Cite: | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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2L2Y
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![BU of 2l2y by Molmil](/molmil-images/mine/2l2y) | Thiostrepton, epimer form of residue 9 | Descriptor: | Thiostrepton | Authors: | Jonker, H.R.A, Baumann, S, Wolf, A, Schoof, S, Hiller, F, Schulte, K.W, Kirschner, K.N, Schwalbe, H, Arndt, H.-D. | Deposit date: | 2010-08-27 | Release date: | 2011-02-02 | Last modified: | 2013-06-26 | Method: | SOLUTION NMR | Cite: | NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew.Chem.Int.Ed.Engl., 50, 2011
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3POK
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![BU of 3pok by Molmil](/molmil-images/mine/3pok) | Interleukin-1-beta LBT L3 Mutant | Descriptor: | Interleukin-1 beta | Authors: | Barthelmes, K, Reynolds, A.M, Peisach, E, Jonker, H.R.A, DeNunzio, N.J, Allen, K.N, Imperiali, B, Schwalbe, H. | Deposit date: | 2010-11-22 | Release date: | 2011-01-19 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Engineering encodable lanthanide-binding tags into loop regions of proteins. J.Am.Chem.Soc., 133, 2011
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8CQ1
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![BU of 8cq1 by Molmil](/molmil-images/mine/8cq1) | |
2LUO
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![BU of 2luo by Molmil](/molmil-images/mine/2luo) | NMR solution structure of apo-MptpA | Descriptor: | LOW MOLECULAR WEIGHT PROTEIN-TYROSINE-PHOSPHATASE A | Authors: | Stehle, T, Sreeramulu, S, Loehr, F, Richter, C, Saxena, K, Jonker, H.R.A, Schwalbe, H. | Deposit date: | 2012-06-19 | Release date: | 2012-08-15 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | The Apo-structure of the Low Molecular Weight Protein-tyrosine Phosphatase A (MptpA) from Mycobacterium tuberculosis Allows for Better Target-specific Drug Development. J.Biol.Chem., 287, 2012
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6F3Y
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![BU of 6f3y by Molmil](/molmil-images/mine/6f3y) | Backbone structure of Des-Arg10-Kallidin (DAKD) peptide bound to human Bradykinin 1 Receptor (B1R) determined by DNP-enhanced MAS SSNMR | Descriptor: | Kininogen-1 | Authors: | Mao, J, Kuenze, G, Joedicke, L, Meiler, J, Michel, H, Glaubitz, C. | Deposit date: | 2017-11-29 | Release date: | 2018-01-10 | Last modified: | 2023-06-14 | Method: | SOLID-STATE NMR | Cite: | The molecular basis of subtype selectivity of human kinin G-protein-coupled receptors. Nat. Chem. Biol., 14, 2018
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