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7PWB
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BU of 7pwb by Molmil
dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP
Descriptor: 1,2-ETHANEDIOL, CITRIC ACID, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PWH
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BU of 7pwh by Molmil
Structure of the dTDP-sugar epimerase StrM
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, THYMIDINE-5'-DIPHOSPHATE, ...
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PWI
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BU of 7pwi by Molmil
Structure of the dTDP-sugar epimerase StrM
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase
Authors:Cross, A.R, Harmer, N.J, Isupov, M.N.
Deposit date:2021-10-06
Release date:2022-04-20
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.326 Å)
Cite:Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PQ9
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BU of 7pq9 by Molmil
Crystal structure of Bacillus clausii pdxR at 2.8 Angstroms resolution
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Vivoli Vega, M, Isupov, M.N, Harmer, N.
Deposit date:2021-09-16
Release date:2022-09-28
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural insights into the DNA recognition mechanism by the bacterial transcription factor PdxR.
Nucleic Acids Res., 51, 2023
7QCA
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BU of 7qca by Molmil
Spraguea lophii ribosome
Descriptor: 40S Ribosomal protein S19, 40S ribosomal protein S0, 40S ribosomal protein S10, ...
Authors:Gil Diez, P, McLaren, M, Isupov, M.N, Daum, B, Conners, R, Williams, B.
Deposit date:2021-11-22
Release date:2022-11-30
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:CryoEM reveals that ribosomes in microsporidian spores are locked in a dimeric hibernating state
Nat Microbiol, 2023
2W43
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BU of 2w43 by Molmil
Structure of L-haloacid dehalogenase from S. tokodaii
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, HYPOTHETICAL 2-HALOALKANOIC ACID DEHALOGENASE, PHOSPHATE ION
Authors:Rye, C.A, Isupov, M.N, Lebedev, A.A, Littlechild, J.A.
Deposit date:2008-11-21
Release date:2008-12-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Biochemical and Structural Studies of a L-Haloacid Dehalogenase from the Thermophilic Archaeon Sulfolobus Tokodaii.
Extremophiles, 13, 2009
2WBM
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BU of 2wbm by Molmil
Crystal structure of mthSBDS, the homologue of the Shwachman-Bodian- Diamond syndrome protein in the euriarchaeon Methanothermobacter thermautotrophicus
Descriptor: CHLORIDE ION, GLYCEROL, RIBOSOME MATURATION PROTEIN SDO1 HOMOLOG, ...
Authors:Ng, C.L, Isupov, M.N, Lebedev, A.A, Ortiz-Lombardia, M, Antson, A.A.
Deposit date:2009-03-02
Release date:2009-06-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Conformational Flexibility and Molecular Interactions of an Archaeal Homologue of the Shwachman-Bodian-Diamond Syndrome Protein.
Bmc Struct.Biol., 9, 2009
2WDU
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BU of 2wdu by Molmil
Fasciola hepatica sigma class GST
Descriptor: BROMIDE ION, DIMETHYL SULFOXIDE, GLUTATHIONE, ...
Authors:Line, K, Isupov, M.N, LaCourse, E.J, Brophy, P.M, Littlechild, J.A.
Deposit date:2009-03-26
Release date:2010-04-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:The 1.6 Angstrom Crystal Structure of the Fasciola Hepatica Sigma Class Gst
To be Published
2WB9
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BU of 2wb9 by Molmil
Fasciola hepatica sigma class GST
Descriptor: BROMIDE ION, CYSTEINE, GLUTATHIONE, ...
Authors:Line, K, Isupov, M.N, LaCourse, J, Brophy, P.M, Littlechild, J.A.
Deposit date:2009-02-23
Release date:2010-03-31
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:The 1.6 Angstrom Crystal Structure of the Fasciola Hepatica Sigma Class Gst
To be Published
2V9P
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BU of 2v9p by Molmil
Crystal structure of papillomavirus E1 hexameric helicase DNA-free form
Descriptor: MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1
Authors:Sanders, C.M, Kovalevskiy, O.V, Sizov, D, Lebedev, A.A, Isupov, M.N, Antson, A.A.
Deposit date:2007-08-24
Release date:2007-10-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Papillomavirus E1 Helicase Assembly Maintains an Asymmetric State in the Absence of DNA and Nucleotide Cofactors.
Nucleic Acids Res., 35, 2007
2WRT
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BU of 2wrt by Molmil
The 2.4 Angstrom structure of the Fasciola hepatica mu class GST, GST26
Descriptor: CHLORIDE ION, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME 51
Authors:Line, K, Isupov, M.N, LaCourse, E.J, Brophy, P.M, Littlechild, J.A.
Deposit date:2009-09-02
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The 2.5 Angstrom Structure of a Mu Class Gst from Fasciola Hepatica
To be Published
2VXI
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BU of 2vxi by Molmil
The binding of heme and zinc in Escherichia coli Bacterioferritin
Descriptor: BACTERIOFERRITIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
Authors:Willies, S.C, Isupov, M.N, Garman, E.F, Littlechild, J.A.
Deposit date:2008-07-04
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:The Binding of Haem and Zinc in the 1.9 A X-Ray Structure of Escherichia Coli Bacterioferritin.
J.Biol.Inorg.Chem., 14, 2009
2VIM
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BU of 2vim by Molmil
X-ray structure of Fasciola hepatica thioredoxin
Descriptor: THIOREDOXIN
Authors:Line, K, Isupov, M.N, Garcia-Rodriguez, E, Maggioli, G, Parra, F, Littlechild, J.A.
Deposit date:2007-12-05
Release date:2008-07-29
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.38 Å)
Cite:The Fasciola Hepatica Thioredoxin: High Resolution Structure Reveals Two Oxidation States.
Mol.Biochem.Parasitol., 161, 2008
2WS2
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BU of 2ws2 by Molmil
The 2 Angstrom structure of a Nu-class GST from Haemonchus contortus
Descriptor: GLUTATHIONE S-TRANSFERASE
Authors:Line, K, Isupov, M.N, vanRossum, A.J, Brophy, P.M, Littlechild, J.A.
Deposit date:2009-09-03
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:The 2 Angstrom Structure of a Nu-Class Gst from Haemonchus Contortus
To be Published
4BA5
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BU of 4ba5 by Molmil
Crystal structure of omega-transaminase from Chromobacterium violaceum
Descriptor: 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, AMINOTRANSFERASE, SULFATE ION
Authors:Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2012-09-11
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
4B98
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BU of 4b98 by Molmil
The structure of the omega aminotransferase from Pseudomonas aeruginosa
Descriptor: 3-[O-PHOSPHONOPYRIDOXYL]--AMINO-BENZOIC ACID, BETA-ALANINE--PYRUVATE TRANSAMINASE, CALCIUM ION, ...
Authors:Sayer, C, Isupov, M.N, Westlake, A, Littlechild, J.A.
Deposit date:2012-09-03
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
4CE6
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BU of 4ce6 by Molmil
Mutagenesis of a Rhodobacteraceae L-haloacid dehalogenase
Descriptor: L-HALOACID DEHALOGENASE
Authors:Novak, H.R, Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2013-11-08
Release date:2014-11-19
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Mutagenesis of a Rhodobacteraceae L-Haloacid Dehalogenase
To be Published
4CF3
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BU of 4cf3 by Molmil
Mutagenesis of a Rhodobacteraceae L-haloacid dehalogenase
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, L-HALOACID DEHALOGENASE
Authors:Novak, H.R, Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2013-11-13
Release date:2014-11-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.16 Å)
Cite:Mutagenesis of a Rhodobacteraceae L-Haloacid Dehalogenase
To be Published
4BA4
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BU of 4ba4 by Molmil
Crystal structure of the apo omega-transaminase from Chromobacterium violaceum
Descriptor: AMINOTRANSFERASE, SULFATE ION
Authors:Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2012-09-11
Release date:2013-03-27
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
4CNQ
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BU of 4cnq by Molmil
Mutagenesis of a Rhodobacteraceae L-haloacid dehalogenase
Descriptor: DI(HYDROXYETHYL)ETHER, L-HALOACID DEHALOGENASE
Authors:Novak, H.R, Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2014-01-23
Release date:2015-02-18
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Mutagenesis of a Rhodobacteraceae L-Haloacid Dehalogenase
To be Published
4B9B
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BU of 4b9b by Molmil
The structure of the omega aminotransferase from Pseudomonas aeruginosa
Descriptor: BETA-ALANINE-PYRUVATE TRANSAMINASE, CALCIUM ION, CHLORIDE ION, ...
Authors:Sayer, C, Isupov, M.N, Westlake, A, Littlechild, J.A.
Deposit date:2012-09-03
Release date:2013-03-27
Last modified:2013-05-08
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
4COQ
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BU of 4coq by Molmil
The complex of alpha-Carbonic anhydrase from Thermovibrio ammonificans with inhibitor sulfanilamide.
Descriptor: 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CARBONATE DEHYDRATASE, CHLORIDE ION, ...
Authors:James, P, Isupov, M.N, Sayer, C, Berg, S, Lioliou, M, Kotlar, H, Littlechild, J.A.
Deposit date:2014-01-30
Release date:2014-10-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability
Acta Crystallogr.,Sect.D, 70, 2014
4AH3
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BU of 4ah3 by Molmil
Crystal structure of the holo omega-transaminase from Chromobacterium violaceum
Descriptor: OMEGA-TRANSAMINASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2012-02-03
Release date:2012-02-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Structural Studies with Pseudomonas and Chromobacterium [Omega]-Aminotransferases Provide Insights Into Their Differing Substrate Specificity.
Acta Crystallogr.,Sect.D, 69, 2013
4CF4
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BU of 4cf4 by Molmil
Mutagenesis of a Rhodobacteraceae L-haloacid dehalogenase
Descriptor: L-HALOACID DEHALOGENASE
Authors:Novak, H.R, Sayer, C, Isupov, M.N, Littlechild, J.A.
Deposit date:2013-11-13
Release date:2014-11-26
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Mutagenesis of a Rhodobacteraceae L-Haloacid Dehalogenase
To be Published
4BQO
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BU of 4bqo by Molmil
Structural insights into WcbI, a novel polysaccharide biosynthesis enzyme. Native protein without disulfide bond between COA and Cys14.
Descriptor: BROMIDE ION, COENZYME A, DI(HYDROXYETHYL)ETHER, ...
Authors:Vivoli, M, Ayres, E, Isupov, M.N, Harmer, N.J.
Deposit date:2013-05-31
Release date:2013-11-06
Last modified:2014-08-13
Method:X-RAY DIFFRACTION (1.56 Å)
Cite:Structural Insights Into Wcbi, a Novel Polysaccharide-Biosynthesis Enzyme.
Iucrj, 1, 2014

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