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7PXH
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BU of 7pxh by Molmil
Emodepside-bound Drosophila Slo channel
Descriptor: (3~{S},6~{R},9~{S},12~{R},15~{S},18~{R},21~{S},24~{R})-4,6,10,16,18,22-hexamethyl-3,9,15,21-tetrakis(2-methylpropyl)-12,24-bis[(4-morpholin-4-ylphenyl)methyl]-1,7,13,19-tetraoxa-4,10,16,22-tetrazacyclotetracosane-2,5,8,11,14,17,20,23-octone, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, ...
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (2.59 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
7PXG
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BU of 7pxg by Molmil
Verruculogen-bound Drosophila Slo channel
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
7PXF
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BU of 7pxf by Molmil
Ca2+ free Drosophila Slo channel
Descriptor: Isoform J of Calcium-activated potassium channel slowpoke, MAGNESIUM ION, POTASSIUM ION
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (2.68 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
7PXE
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BU of 7pxe by Molmil
Ca2+ bound Drosophila Slo channel
Descriptor: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
Authors:Raisch, T, Brockmann, A, Ebbinghaus-Kintscher, U, Freigang, J, Gutbrod, O, Kubicek, J, Maertens, B, Hofnagel, O, Raunser, S.
Deposit date:2021-10-08
Release date:2021-12-15
Last modified:2021-12-22
Method:ELECTRON MICROSCOPY (2.38 Å)
Cite:Small molecule modulation of the Drosophila Slo channel elucidated by cryo-EM.
Nat Commun, 12, 2021
4E7W
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BU of 4e7w by Molmil
Structure of GSK3 from Ustilago maydis
Descriptor: Glycogen Synthase Kinase 3
Authors:Gruetter, C, Rauh, D.
Deposit date:2012-03-19
Release date:2012-05-16
Last modified:2023-12-06
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Targeting GSK3 from Ustilago maydis: Type-II Kinase Inhibitors as Potential Antifungals.
Acs Chem.Biol., 7, 2012
3QBN
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BU of 3qbn by Molmil
Structure of Human Aurora A in Complex with a diaminopyrimidine
Descriptor: 5-chloro-N~4~-cyclopropyl-N~2~-[4-(2-methoxyethoxy)phenyl]pyrimidine-2,4-diamine, Serine/threonine-protein kinase 6
Authors:Gruetter, C, Simard, J.R, Rauh, D.
Deposit date:2011-01-13
Release date:2012-01-18
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Identification of Ustilago maydis Aurora kinase as a novel antifungal target.
Acs Chem.Biol., 6, 2011

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