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1CV9
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BU of 1cv9 by Molmil
NMR STUDY OF ITAM PEPTIDE SUBSTRATE
Descriptor: IG-ALPHA ITAM PEPTIDE
Authors:Gaul, B.S, Harrison, M.L, Geahlen, R.L, Post, C.B.
Deposit date:1999-08-23
Release date:1999-08-31
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptor.
J.Biol.Chem., 275, 2000
2FCI
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BU of 2fci by Molmil
Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase
Descriptor: C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759, Doubly phosphorylated peptide derived from Syk kinase comprising residues 338-350
Authors:Groesch, T.D, Zhou, F, Mattila, S, Geahlen, R.L, Post, C.B.
Deposit date:2005-12-12
Release date:2006-01-31
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase
J.Mol.Biol., 356, 2006
2MC1
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BU of 2mc1 by Molmil
Solution structure of the Vav1 SH2 domain complexed with a Syk-derived singly phosphorylated peptide
Descriptor: Proto-oncogene vav, Tyrosine-protein kinase SYK
Authors:Chen, C, Piraner, D, Gorenstein, N.M, Geahlen, R.L, Post, C.B.
Deposit date:2013-08-13
Release date:2013-08-28
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Differential recognition of syk-binding sites by each of the two phosphotyrosine-binding pockets of the Vav SH2 domain.
Biopolymers, 99, 2013
2LCT
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BU of 2lct by Molmil
Solution structure of the Vav1 SH2 domain complexed with a Syk-derived doubly phosphorylated peptide
Descriptor: Proto-oncogene vav, Tyrosine-protein kinase SYK
Authors:Chen, C, Gorenstein, N, Post, C.
Deposit date:2011-05-09
Release date:2011-06-01
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Two closely spaced tyrosines regulate NFAT signaling in B cells via Syk association with Vav.
Mol.Cell.Biol., 31, 2011

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