3NQ0
| Crystal Structure of Tyrosinase from Bacillus megaterium crystallized in the absence of Zinc | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Sendovski, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2010-06-29 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | First structures of an active bacterial tyrosinase reveal copper plasticity. J.Mol.Biol., 405, 2011
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4HD6
| Crystal Structure of Tyrosinase from Bacillus megaterium V218F mutant soaked in CuSO4 | Descriptor: | COPPER (II) ION, Tyrosinase | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2012-10-02 | Release date: | 2013-01-23 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Influencing the monophenolase/diphenolase activity ratio in tyrosinase. Biochim.Biophys.Acta, 1834, 2013
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5I3A
| Crystal Structure of tyrosinase from Bacillus megaterium with configuration A of hydroquinone inhibitor in the active site | Descriptor: | Tyrosinase, ZINC ION, benzene-1,4-diol | Authors: | Kanteev, M, Deri, B, Adir, N, Fishman, A. | Deposit date: | 2016-02-10 | Release date: | 2016-10-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The unravelling of the complex pattern of tyrosinase inhibition. Sci Rep, 6, 2016
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5I3B
| Crystal Structure of tyrosinase from Bacillus megaterium with configuration B of hydroquinone inhibitor in the active site | Descriptor: | Tyrosinase, ZINC ION, benzene-1,4-diol | Authors: | Kanteev, M, Deri, B, Adir, N, Fishman, A. | Deposit date: | 2016-02-10 | Release date: | 2016-10-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The unravelling of the complex pattern of tyrosinase inhibition. Sci Rep, 6, 2016
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5I38
| Crystal Structure of tyrosinase from Bacillus megaterium with inhibitor kojic acid in the active site | Descriptor: | 5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE, COPPER (II) ION, Tyrosinase | Authors: | Kanteev, M, Goldfeder, M, Deri, B, Adir, N, Fishman, A. | Deposit date: | 2016-02-10 | Release date: | 2016-10-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | The unravelling of the complex pattern of tyrosinase inhibition. Sci Rep, 6, 2016
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4P6S
| Crystal Structure of tyrosinase from Bacillus megaterium with L-DOPA in the active site | Descriptor: | 3,4-DIHYDROXYPHENYLALANINE, Tyrosinase, ZINC ION | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2014-03-25 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins. Nat Commun, 5, 2014
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4P6R
| Crystal Structure of tyrosinase from Bacillus megaterium with tyrosine in the active site | Descriptor: | TYROSINE, Tyrosinase, ZINC ION | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2014-03-25 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins. Nat Commun, 5, 2014
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4P6T
| Crystal Structure of tyrosinase from Bacillus megaterium with p-tyrosol in the active site | Descriptor: | 4-(2-hydroxyethyl)phenol, COPPER (II) ION, Tyrosinase | Authors: | Goldfeder, M, Kanteev, M, Adir, N, Fishman, A. | Deposit date: | 2014-03-25 | Release date: | 2014-07-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins. Nat Commun, 5, 2014
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6EM0
| Crystal Structure of 2-hydroxybiphenyl 3-monooxygenase M321A from Pseudomonas azelaica | Descriptor: | 2-hydroxybiphenyl-3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Deri, B, Bregman-Cohen, A, Pazy Benhar, Y, Fishman, A. | Deposit date: | 2017-10-01 | Release date: | 2018-01-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.78 Å) | Cite: | Altering 2-Hydroxybiphenyl 3-Monooxygenase Regioselectivity by Protein Engineering for the Production of a New Antioxidant. Chembiochem, 19, 2018
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4D87
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6EI4
| Crystal Structure of tyrosinase from Bacillus megaterium with B5N inhibitor in the active site | Descriptor: | COPPER (II) ION, Tyrosinase, [4-[(4-fluorophenyl)methyl]piperazin-1-yl]-(2-methylphenyl)methanone | Authors: | Deri, B, Gitto, R, Pazy Benhar, Y, Fishman, A. | Deposit date: | 2017-09-17 | Release date: | 2018-04-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J. Med. Chem., 61, 2018
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6FZC
| Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant L184F/L360F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
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6FZ9
| Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A187F/L360F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2463 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
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6FZA
| Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant A187F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
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6FZ8
| Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L184F/A187F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
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6FZD
| Crystal Structure of lipase from Geobacillus stearothermophilus T6 variant L184F/A187F/L360F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-14 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
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6FZ1
| Crystal Structure of lipase from Geobacillus stearothermophilus T6 methanol stable variant L360F | Descriptor: | CALCIUM ION, Lipase, ZINC ION | Authors: | Gihaz, S, Kanteev, M, Pazy, Y, Fishman, A. | Deposit date: | 2018-03-13 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Filling the Void: Introducing Aromatic Interactions into Solvent Tunnels To Enhance Lipase Stability in Methanol. Appl.Environ.Microbiol., 84, 2018
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