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1U9N
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BU of 1u9n by Molmil
Crystal structure of the transcriptional regulator EthR in a ligand bound conformation opens therapeutic perspectives against tuberculosis and leprosy
Descriptor: HEXADECYL OCTANOATE, Transcriptional repressor EthR
Authors:Frenois, F, Engohang-Ndong, J, Locht, C, Baulard, A.R, Villeret, V.
Deposit date:2004-08-10
Release date:2004-11-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of EthR in a Ligand Bound Conformation Reveals Therapeutic Perspectives against Tuberculosis
Mol.Cell, 16, 2004
1U9O
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BU of 1u9o by Molmil
Crystal structure of the transcriptional regulator EthR in a ligand bound conformation
Descriptor: HEXADECYL OCTANOATE, Transcriptional repressor EthR
Authors:Frenois, F, Engohang-Ndong, J, Locht, C, Baulard, A.R, Villeret, V.
Deposit date:2004-08-10
Release date:2004-11-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structure of EthR in a Ligand Bound Conformation Reveals Therapeutic Perspectives against Tuberculosis
Mol.Cell, 16, 2004
2PMU
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BU of 2pmu by Molmil
Crystal structure of the DNA-binding domain of PhoP
Descriptor: CHLORIDE ION, GLYCINE, PHOSPHATE ION, ...
Authors:Wang, S.
Deposit date:2007-04-23
Release date:2008-02-26
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.779 Å)
Cite:Structure of the DNA-binding domain of the response regulator PhoP from Mycobacterium tuberculosis
Biochemistry, 46, 2007
3G1O
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BU of 3g1o by Molmil
EthR from Mycobacterium tuberculosis in complex with compound BDM14500
Descriptor: TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR, tert-butyl 4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine-1-carboxylate
Authors:Willand, N, Dirie, B, Carette, X, Bifani, P, Singhal, A, Desroses, M, Leroux, F, Willery, E, Mathys, V, Deprez-Poulain, R, Delcroix, G, Frenois, F, Aumercier, M, Locht, C, Villeret, V, Deprez, B, Baulard, A.R.
Deposit date:2009-01-30
Release date:2009-07-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
NAT.MED. (N.Y.), 15, 2009
3G1L
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BU of 3g1l by Molmil
EthR from Mycobacterium tuberculosis in complex with compound BDM14744
Descriptor: 3-(4-fluorophenyl)-5-phenyl-4H-1,2,4-triazole, TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR
Authors:Willand, N, Dirie, B, Carette, X, Bifani, P, Singhal, A, Desroses, M, Leroux, F, Willery, E, Mathys, V, Deprez-Poulain, R, Delcroix, G, Frenois, F, Aumercier, M, Locht, C, Villeret, V, Deprez, B, Baulard, A.R.
Deposit date:2009-01-30
Release date:2009-07-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Nat.Med. (N.Y.), 15, 2009
3G1M
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BU of 3g1m by Molmil
EthR from Mycobacterium tuberculosis in complex with compound BDM31381
Descriptor: 1-(thiophen-2-ylacetyl)-4-(3-thiophen-2-yl-1,2,4-oxadiazol-5-yl)piperidine, TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR
Authors:Willand, N, Dirie, B, Carette, X, Bifani, P, Singhal, A, Desroses, M, Leroux, F, Willery, E, Mathys, V, Deprez-Poulain, R, Delcroix, G, Frenois, F, Aumercier, M, Locht, C, Villeret, V, Deprez, B, Baulard, A.R.
Deposit date:2009-01-30
Release date:2009-07-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Synthetic EthR inhibitors boost antituberculous activity of ethionamide.
Nat.Med. (N.Y.), 15, 2009

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