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1CSG
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BU of 1csg by Molmil
Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor
Descriptor: Granulocyte-macrophage colony-stimulating factor
Authors:Walter, M.R, Cook, W.J, Ealick, S.E.
Deposit date:1992-11-23
Release date:1993-10-31
Last modified:2016-01-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Three-dimensional structure of recombinant human granulocyte-macrophage colony-stimulating factor.
J.Mol.Biol., 224, 1992
1FG9
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BU of 1fg9 by Molmil
3:1 COMPLEX OF INTERFERON-GAMMA RECEPTOR WITH INTERFERON-GAMMA DIMER
Descriptor: INTERFERON GAMMA, INTERFERON-GAMMA RECEPTOR ALPHA CHAIN
Authors:Thiel, D.J, le Du, M.-H, Walter, R.L, D'Arcy, A, Chene, C, Fountoulakis, M, Garotta, G, Winkler, F.K, Ealick, S.E.
Deposit date:2000-07-28
Release date:2000-08-11
Last modified:2022-12-21
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Observation of an unexpected third receptor molecule in the crystal structure of human interferon-gamma receptor complex.
Structure Fold.Des., 8, 2000
1EKK
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BU of 1ekk by Molmil
CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN THE R3 FORM WITH HYDROXYETHYLTHIAZOLE
Descriptor: 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, HYDROXYETHYLTHIAZOLE KINASE, SULFUR DIOXIDE
Authors:Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E.
Deposit date:2000-03-09
Release date:2000-08-09
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
1F8Y
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CRYSTAL STRUCTURE ANALYSIS OF NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE COMPLEXED WITH 5-METHYL-2'-DEOXYPSEUDOURIDINE
Descriptor: 2'-deoxy-1-methyl-pseudouridine, NUCLEOSIDE 2-DEOXYRIBOSYLTRANSFERASE
Authors:Armstrong, S.R, Cook, W.J, Short, S.A, Ealick, S.E.
Deposit date:2000-07-05
Release date:2000-08-09
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structures of nucleoside 2-deoxyribosyltransferase in native and ligand-bound forms reveal architecture of the active site.
Structure, 4, 1996
1PR4
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BU of 1pr4 by Molmil
Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-ribofuranosyl-6-methylthiopurine and Phosphate/Sulfate
Descriptor: 2-HYDROXYMETHYL-5-(6-METHYLSULFANYL-PURIN-9-YL)-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PK7
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with adenosine and sulfate/phosphate
Descriptor: ADENOSINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PK9
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 2-fluoroadenosine and sulfate/phosphate
Descriptor: 2-(6-AMINO-2-FLUORO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PKE
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 2-fluoro-2'-deoxyadenosine and sulfate/phosphate
Descriptor: 5-(6-AMINO-2-FLUORO-PURIN-9-YL)-2-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-OL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-05
Release date:2003-11-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1NG3
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Complex of ThiO (glycine oxidase) with acetyl-glycine
Descriptor: ACETYLAMINO-ACETIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, Glycine oxidase, ...
Authors:Settembre, E.C, Dorrestein, P.C, Park, J, Augustine, A, Begley, T.P, Ealick, S.E.
Deposit date:2002-12-16
Release date:2003-04-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural and Mechanistic Studies on ThiO, a Glycine Oxidase Essential for Thiamin Biosynthesis in Bacillus subtilis
Biochemistry, 42, 2003
1ECP
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BU of 1ecp by Molmil
PURINE NUCLEOSIDE PHOSPHORYLASE
Descriptor: PURINE NUCLEOSIDE PHOSPHORYLASE
Authors:Mao, C, Ealick, S.E.
Deposit date:1995-07-13
Release date:1996-06-20
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The crystal structure of Escherichia coli purine nucleoside phosphorylase: a comparison with the human enzyme reveals a conserved topology.
Structure, 5, 1997
1PR6
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Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-xylofuranosyladenine and Phosphate/Sulfate
Descriptor: 2-(6-AMINO-OCTAHYDRO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1EKQ
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BU of 1ekq by Molmil
CRYSTAL STRUCTURE OF HYDROXYETHYLTHIAZOLE KINASE IN R3 SPACE GROUP
Descriptor: HYDROXYETHYLTHIAZOLE KINASE
Authors:Campobasso, N, Mathews, I.I, Begley, T.P, Ealick, S.E.
Deposit date:2000-03-09
Release date:2000-08-09
Last modified:2014-11-12
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of 4-methyl-5-beta-hydroxyethylthiazole kinase from Bacillus subtilis at 1.5 A resolution.
Biochemistry, 39, 2000
1PR5
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BU of 1pr5 by Molmil
Escherichia coli Purine Nucleoside Phosphorylase Complexed with 7-deazaadenosine and Phosphate/Sulfate
Descriptor: '2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR0
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BU of 1pr0 by Molmil
Escherichia coli Purine Nucleoside Phosphorylase Complexed with Inosine and Phosphate/Sulfate
Descriptor: INOSINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR2
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Escherichia coli Purine Nucleoside Phosphorylase Complexed with 9-beta-D-[2-deoxyribofuranosyl]-6-methylpurine and Phosphate/Sulfate
Descriptor: 9-(2-DEOXY-BETA-D-RIBOFURANOSYL)-6-METHYLPURINE, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PW7
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Crystal Structure of E. coli purine nucleoside phosphorylase complexed with 9-beta-D-arabinofuranosyladenine and sulfate/phosphate
Descriptor: 2-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL, PHOSPHATE ION, Purine nucleoside phosphorylase DeoD-type
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-30
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PR1
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BU of 1pr1 by Molmil
Escherichia coli Purine Nucleoside Phosphorylase Complexed with Formycin B and Phosphate/Sulfate
Descriptor: FORMYCIN B, PHOSPHATE ION, Purine nucleoside phosphorylase
Authors:Bennett, E.M, Li, C, Allan, P.W, Parker, W.B, Ealick, S.E.
Deposit date:2003-06-19
Release date:2003-11-25
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase.
J.Biol.Chem., 278, 2003
1PBN
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BU of 1pbn by Molmil
PURINE NUCLEOSIDE PHOSPHORYLASE
Descriptor: PURINE NUCLEOSIDE PHOSPHORYLASE
Authors:Mao, C, Ealick, S.E.
Deposit date:1995-07-10
Release date:1995-11-14
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Calf spleen purine nucleoside phosphorylase complexed with substrates and substrate analogues.
Biochemistry, 37, 1998
1CG6
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BU of 1cg6 by Molmil
STRUCTURE OF HUMAN 5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE COMPLEXED WITH 5'-DEOXY-5'-METHYLTHIOADENOSINE AND SULFATE AT 1.7 A RESOLUTION
Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, PROTEIN (5'-DEOXY-5'-METHYLTHIOADENOSINE PHOSPHORYLASE), SULFATE ION
Authors:Appleby, T.C, Erion, M.D, Ealick, S.E.
Deposit date:1999-03-27
Release date:1999-07-05
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase at 1.7 A resolution provides insights into substrate binding and catalysis.
Structure Fold.Des., 7, 1999
1CLI
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BU of 1cli by Molmil
X-RAY CRYSTAL STRUCTURE OF AMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE (PURM), FROM THE E. COLI PURINE BIOSYNTHETIC PATHWAY, AT 2.5 A RESOLUTION
Descriptor: PROTEIN (PHOSPHORIBOSYL-AMINOIMIDAZOLE SYNTHETASE), SULFATE ION
Authors:Li, C, Kappock, T.J, Stubbe, J, Weaver, T.M, Ealick, S.E.
Deposit date:1999-04-28
Release date:1999-10-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:X-ray crystal structure of aminoimidazole ribonucleotide synthetase (PurM), from the Escherichia coli purine biosynthetic pathway at 2.5 A resolution.
Structure Fold.Des., 7, 1999
1S2D
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BU of 1s2d by Molmil
Purine 2'-Deoxyribosyl complex with arabinoside: Ribosylated Intermediate (AraA)
Descriptor: 2-deoxy-2-fluoro-alpha-D-arabinofuranose, ADENINE, Nucleoside 2-deoxyribosyltransferase
Authors:Anand, R, Kaminski, P.A, Ealick, S.E.
Deposit date:2004-01-08
Release date:2004-03-30
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution.
Biochemistry, 43, 2004
1S3F
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BU of 1s3f by Molmil
Purine 2'-deoxyribosyltransferase + selenoinosine
Descriptor: 9-(3,4-DIHYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1,9-DIHYDRO-PURINE-6-THIONE, purine trans deoxyribosylase
Authors:Anand, R, Kaminski, P.A, Ealick, S.E.
Deposit date:2004-01-13
Release date:2004-03-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution.
Biochemistry, 43, 2004
1S2L
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Purine 2'deoxyribosyltransferase native structure
Descriptor: purine trans deoxyribosylase
Authors:Anand, R, Kaminski, P.A, Ealick, S.E.
Deposit date:2004-01-08
Release date:2004-03-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution.
Biochemistry, 43, 2004
1S2G
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BU of 1s2g by Molmil
Purine 2'deoxyribosyltransferase + 2'-deoxyadenosine
Descriptor: (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, purine trans deoxyribosylase
Authors:Anand, R, Kaminski, P.A, Ealick, S.E.
Deposit date:2004-01-08
Release date:2004-03-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution.
Biochemistry, 43, 2004
1S2I
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Purine 2'deoxyribosyltransferase + bromopurine
Descriptor: 6-BROMO-7H-PURINE, purine trans deoxyribosylase
Authors:Anand, R, Kaminski, P.A, Ealick, S.E.
Deposit date:2004-01-08
Release date:2004-03-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution.
Biochemistry, 43, 2004

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