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6F15
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BU of 6f15 by Molmil
GLIC mutant H127Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0M
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BU of 6f0m by Molmil
GLIC mutant E35Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F16
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BU of 6f16 by Molmil
GLIC mutant H277Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F10
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BU of 6f10 by Molmil
GLIC mutant D88N
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0R
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BU of 6f0r by Molmil
GLIC mutant E82Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F12
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BU of 6f12 by Molmil
GLIC mutant E181A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0U
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BU of 6f0u by Molmil
GLIC mutant E35A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0Z
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BU of 6f0z by Molmil
GLIC mutant D88N
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F11
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BU of 6f11 by Molmil
GLIC mutant D86A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0I
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BU of 6f0i by Molmil
GLIC mutant E26A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Method:X-RAY DIFFRACTION (3 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0V
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BU of 6f0v by Molmil
GLIC mutant E82Q
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F0J
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BU of 6f0j by Molmil
GLIC mutant E26A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-20
Release date:2018-01-10
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6F13
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BU of 6f13 by Molmil
GLIC mutant E75A
Descriptor: ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ...
Authors:Hu, H.D, Delarue, M.
Deposit date:2017-11-21
Release date:2018-01-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
6FL9
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BU of 6fl9 by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Wild type 2.3 Angstrom resolution
Descriptor: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside
Authors:Hu, H, Delarue, M.
Deposit date:2018-01-25
Release date:2018-05-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FLI
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BU of 6fli by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - Co-crystallization with 4-bromo cinnamic acid
Descriptor: 3-(4-bromophenyl)propanoic acid, Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside
Authors:Hu, H, Delarue, M.
Deposit date:2018-01-26
Release date:2018-05-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FVR
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BU of 6fvr by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Cesium ions (Cs+)
Descriptor: CESIUM ION, Cys-loop ligand-gated ion channel, nonyl beta-D-glucopyranoside
Authors:Hu, H, Delarue, M.
Deposit date:2018-03-05
Release date:2018-05-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (4.2 Å)
Cite:Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FVS
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BU of 6fvs by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - sTeLIC in complex with Barium ions (Ba2+)
Descriptor: BARIUM ION, Cys-loop ligand-gated ion channel, ZINC ION, ...
Authors:Hu, H, Delarue, M.
Deposit date:2018-03-05
Release date:2018-05-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6FVQ
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BU of 6fvq by Molmil
The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - R86A
Descriptor: Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside
Authors:Hu, H, Delarue, M.
Deposit date:2018-03-05
Release date:2018-05-16
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6HJA
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BU of 6hja by Molmil
Xray structure of GLIC in complex with glutarate
Descriptor: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECANE, ...
Authors:Fourati, Z, Delarue, M.
Deposit date:2018-09-03
Release date:2019-09-18
Last modified:2020-07-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
6HJ3
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BU of 6hj3 by Molmil
Xray structure of GLIC in complex with fumarate
Descriptor: CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ...
Authors:Fourati, Z, Delarue, M.
Deposit date:2018-08-31
Release date:2019-09-11
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural evidence for the binding of monocarboxylates and dicarboxylates at pharmacologically relevant extracellular sites of a pentameric ligand-gated ion channel.
Acta Crystallogr D Struct Biol, 76, 2020
4FLY
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BU of 4fly by Molmil
Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA polymerase 1, MAGNESIUM ION, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2012-06-15
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
J.Mol.Biol., 423, 2012
4FLX
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BU of 4flx by Molmil
Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA polymerase 1, GLYCEROL, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2012-06-15
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
J.Mol.Biol., 423, 2012
4FLW
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BU of 4flw by Molmil
Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA polymerase 1, GLYCEROL, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2012-06-15
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
J.Mol.Biol., 423, 2012
4FM2
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BU of 4fm2 by Molmil
Pyrococcus abyssi B family DNA polymerase (triple mutant) bound to a dsDNA, in edition mode
Descriptor: DNA polymerase 1, GLYCEROL, MAGNESIUM ION, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2012-06-15
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
J.Mol.Biol., 423, 2012
4FLT
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BU of 4flt by Molmil
Pyrococcus abyssi B family DNA polymerase bound to a dsDNA, in edition mode
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA polymerase 1, GLYCEROL, ...
Authors:Gouge, J, Delarue, M.
Deposit date:2012-06-15
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Molecular Recognition of Canonical and Deaminated Bases by P. abyssi Family B DNA Polymerase.
J.Mol.Biol., 423, 2012

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