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2PY4
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BU of 2py4 by Molmil
Full length structure of the Mycobacterium tuberculosis dUTPase complexed with magnesium and alpha,beta-imido-dUTP.
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, ...
Authors:Barabas, O, Nagy, N, Takacs, E, Vertessy, B.G.
Deposit date:2007-05-15
Release date:2007-05-22
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.49 Å)
Cite:Active site of mycobacterial dUTPase: structural characteristics and a built-in sensor.
Biochem.Biophys.Res.Commun., 373, 2008
8C3T
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BU of 8c3t by Molmil
Structure of the GIsul2 transposon excisionase
Descriptor: AlpA family phage regulatory protein
Authors:Smyshlyaev, G, Arinkin, V, Barabas, O.
Deposit date:2022-12-28
Release date:2024-01-10
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Cryo-EM structures of transposon end complexes explain antibiotic resistance transfer across diverse bacteria
To Be Published
3EHW
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BU of 3ehw by Molmil
Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, MAGNESIUM ION, dUTP pyrophosphatase
Authors:Takacs, E, Barabas, O, Vertessy, B.G.
Deposit date:2008-09-15
Release date:2008-09-30
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Human dUTPase in complex with alpha,beta-imido-dUTP and Mg2+: visualization of the full-length C-termini in all monomers and suggestion for an additional metal ion binding site
To be Published
6ZK6
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BU of 6zk6 by Molmil
Protein Phosphatase 1 (PP1) T320E mutant
Descriptor: FE (III) ION, MANGANESE (II) ION, PHOSPHATE ION, ...
Authors:Salvi, F, Barabas, O, Koehn, M.
Deposit date:2020-06-29
Release date:2020-11-18
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Towards Dissecting the Mechanism of Protein Phosphatase-1 Inhibition by Its C-Terminal Phosphorylation.
Chembiochem, 22, 2021
4H4A
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BU of 4h4a by Molmil
Crystal structure of the C-terminal domain of Drosophila melanogaster Zucchini
Descriptor: Mitochondrial cardiolipin hydrolase
Authors:Voigt, F, Schulz, E.C, Barabas, O.
Deposit date:2012-09-17
Release date:2012-11-07
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the primary piRNA biogenesis factor Zucchini reveals similarity to the bacterial PLD endonuclease Nuc.
Rna, 18, 2012
4PNO
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BU of 4pno by Molmil
Escherichia coli Hfq-RNA complex at 0.97 A Resolution
Descriptor: RNA-binding protein Hfq, URIDINE-5'-MONOPHOSPHATE
Authors:Schulz, E.C, Barabas, O.
Deposit date:2014-05-24
Release date:2014-11-19
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.97 Å)
Cite:Structure of an Escherichia coli Hfq:RNA complex at 0.97 angstrom resolution.
Acta Crystallogr.,Sect.F, 70, 2014
5CR4
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BU of 5cr4 by Molmil
Crystal structure of the Sleeping Beauty transposase catalytic domain
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CITRIC ACID, GLYCEROL, ...
Authors:Voigt, F, Barabas, O.
Deposit date:2015-07-22
Release date:2016-03-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Sleeping Beauty transposase structure allows rational design of hyperactive variants for genetic engineering.
Nat Commun, 7, 2016
3ECY
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BU of 3ecy by Molmil
Crystal structural analysis of Drosophila melanogaster dUTPase
Descriptor: CG4584-PA, isoform A (BcDNA.LD08534)
Authors:Takacs, E, Barabas, O, Vertessy, B.G.
Deposit date:2008-09-02
Release date:2008-10-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Molecular shape and prominent role of beta-strand swapping in organization of dUTPase oligomers.
Febs Lett., 583, 2009
5JK0
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BU of 5jk0 by Molmil
Crystal structure of XerH site-specific recombinase bound to difH substrate: pre-cleavage complex
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Bebel, A, Barabas, O.
Deposit date:2016-04-25
Release date:2016-12-28
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.
Elife, 5, 2016
5JJV
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BU of 5jjv by Molmil
Crystal structure of XerH site-specific recombinase bound to palindromic difH substrate: post-cleavage complex
Descriptor: CHLORIDE ION, DNA (5'-D(*TP*AP*GP*TP*TP*AP*TP*GP*AP*AP*AP*AP*C)-3'), DNA (5'-D(*TP*GP*CP*AP*GP*TP*TP*TP*TP*CP*AP*TP*AP*AP*CP*TP*A)-3'), ...
Authors:Bebel, A, Barabas, O.
Deposit date:2016-04-25
Release date:2016-12-28
Last modified:2018-09-19
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending.
Elife, 5, 2016
2D4M
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BU of 2d4m by Molmil
Crystal Structure of apo M-PMV dUTPase
Descriptor: DU
Authors:Nemeth, V, Barabas, O, Vertessy, G.B.
Deposit date:2005-10-20
Release date:2006-11-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins.
Nucleic Acids Res., 35, 2007
2D4L
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BU of 2d4l by Molmil
Crystal structure of truncated in C-terminal M-PMV dUTPase
Descriptor: DU
Authors:Nemeth, V, Barabas, O, Vertessy, G.B.
Deposit date:2005-10-20
Release date:2006-11-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins.
Nucleic Acids Res., 35, 2007
2D4N
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BU of 2d4n by Molmil
Crystal Structure of M-PMV dUTPase complexed with dUPNPP, substrate analogue
Descriptor: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DU, ...
Authors:Nemeth, V, Barabas, O, Vertessy, G.B.
Deposit date:2005-10-20
Release date:2006-11-21
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Flexible segments modulate co-folding of dUTPase and nucleocapsid proteins.
Nucleic Acids Res., 35, 2007
2XM3
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BU of 2xm3 by Molmil
Deinococcus radiodurans ISDra2 Transposase Left end DNA complex
Descriptor: 5'-D(*TP*TP*AP*GP*T)-3', ACETATE ION, DRA2 TRANSPOSASE BINDING ELEMENT, ...
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-07-22
Release date:2010-10-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
2XO6
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BU of 2xo6 by Molmil
DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE Y132F MUTANT COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE
Descriptor: 5'-D(*TP*TP*GP*AP*TP*G)-3', ACETATE ION, CADMIUM ION, ...
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-08-09
Release date:2010-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
2XQC
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BU of 2xqc by Molmil
DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE COMPLEXED WITH LEFT END RECOGNITION AND CLEAVAGE SITE AND ZN
Descriptor: 5'-D(TP*TP*GP*AP*TP*GP)-3', DRA2 TRANSPOSASE LEFT END RECOGNITION SEQUENCE, TRANSPOSASE, ...
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-09-01
Release date:2010-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
2XMA
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BU of 2xma by Molmil
DEINOCOCCUS RADIODURANS ISDRA2 TRANSPOSASE RIGHT END DNA COMPLEX
Descriptor: DRA2 TRANSPOSASE RIGHT END RECOGNITION SITE, MAGNESIUM ION, TRANSPOSASE
Authors:Hickman, A.B, James, J.A, Barabas, O, Pasternak, C, Ton-Hoang, B, Chandler, M, Sommer, S, Dyda, F.
Deposit date:2010-07-26
Release date:2010-10-13
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:DNA Recognition and the Precleavage State During Single-Stranded DNA Transposition in D. Radiodurans.
Embo J., 29, 2010
5NEW
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BU of 5new by Molmil
RNA-RNA base stacking in the crystal structure of an Hfq6:RNA dimer
Descriptor: RNA (5'-R(P*AP*AP*AP*AP*AP*A)-3'), RNA (5'-R(P*UP*U)-3'), RNA-binding protein Hfq, ...
Authors:Schulz, E.C, Barabas, O.
Deposit date:2017-03-12
Release date:2017-10-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.511 Å)
Cite:Intermolecular base stacking mediates RNA-RNA interaction in a crystal structure of the RNA chaperone Hfq.
Sci Rep, 7, 2017
2QY0
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BU of 2qy0 by Molmil
Active dimeric structure of the catalytic domain of C1r reveals enzyme-product like contacts
Descriptor: Complement C1r subcomponent, GLYCEROL
Authors:Kardos, J, Harmat, V, Pallo, A, Barabas, O, Szilagyi, K, Graf, L, Naray-Szabo, G, Goto, Y, Zavodszky, P, Gal, P.
Deposit date:2007-08-13
Release date:2008-02-05
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Revisiting the mechanism of the autoactivation of the complement protease C1r in the C1 complex: Structure of the active catalytic region of C1r.
Mol.Immunol., 45, 2008
6EN0
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BU of 6en0 by Molmil
Structure of the Tn1549 transposon Integrase (aa 82-397) in complex with circular intermediate DNA (CI5-DNA)
Descriptor: DNA (44-MER), Int protein
Authors:Rubio-Cosials, A, Barabas, O.
Deposit date:2017-10-04
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Cell, 173, 2018
6EMY
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BU of 6emy by Molmil
Structure of the Tn1549 transposon Integrase (aa 82-397, Y379F) in complex with transposon right end DNA
Descriptor: DNA (20-MER), DNA (26-MER), Int protein
Authors:Schulz, E.C, Rubio-Cosials, A, Barabas, O.
Deposit date:2017-10-04
Release date:2018-04-04
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Cell, 173, 2018
6EN2
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BU of 6en2 by Molmil
Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with a circular intermediate DNA (CI6b-DNA)
Descriptor: DI(HYDROXYETHYL)ETHER, DNA (45-MER), Int protein
Authors:Rubio-Cosials, A, Barabas, O.
Deposit date:2017-10-04
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Cell, 173, 2018
6EN1
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BU of 6en1 by Molmil
Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with a circular intermediate DNA (CI6a-DNA)
Descriptor: DI(HYDROXYETHYL)ETHER, DNA (45-MER), Int protein
Authors:Rubio-Cosials, A, Barabas, O.
Deposit date:2017-10-04
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.67 Å)
Cite:Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Cell, 173, 2018
6EMZ
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BU of 6emz by Molmil
Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with circular intermediate DNA (CI5-DNA)
Descriptor: DNA (44-MER), Int protein
Authors:Rubio-Cosials, A, Barabas, O.
Deposit date:2017-10-04
Release date:2018-04-04
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Transposase-DNA Complex Structures Reveal Mechanisms for Conjugative Transposition of Antibiotic Resistance.
Cell, 173, 2018
6FI8
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BU of 6fi8 by Molmil
Crystal structure of the IS608 transposase in complex with left end 29-mer DNA hairpin and a 6-mer DNA representing the intact target site: pre-cleavage target capture complex
Descriptor: CALCIUM ION, DNA 29-MER (LE29), DNA 6-MER (T6'), ...
Authors:Morero, N.R, Barabas, O.
Deposit date:2018-01-17
Release date:2018-03-28
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.598 Å)
Cite:Targeting IS608 transposon integration to highly specific sequences by structure-based transposon engineering.
Nucleic Acids Res., 46, 2018

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