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1N4U
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BU of 1n4u by Molmil
CHOLESTEROL OXIDASE FROM STREPTOMYCES @ pH 4.5 (STREPTOMYCES SP. SA-COO)
Descriptor: Cholesterol oxidase, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Vrielink, A, Lario, P.I.
Deposit date:2002-11-01
Release date:2004-04-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment
Nat.Chem.Biol., 2, 2006
1N4W
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BU of 1n4w by Molmil
ATOMIC RESOLUTION STRUCTURE OF CHOLESTEROL OXIDASE @ pH 7.3 (STREPTOMYCES SP. SA-COO)
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Vrielink, A, Lario, P.I.
Deposit date:2002-11-01
Release date:2004-04-27
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Atomic resolution crystallography reveals how changes in pH shape the protein microenvironment
Nat.Chem.Biol., 2, 2006
4REK
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BU of 4rek by Molmil
Crystal structure and charge density studies of cholesterol oxidase from Brevibacterium sterolicum at 0.74 ultra-high resolution
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION
Authors:Zarychta, B, Lyubimov, A, Ahmed, M, Munshi, P, Guillot, B, Vrielink, A.
Deposit date:2014-09-23
Release date:2015-04-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (0.74 Å)
Cite:Cholesterol oxidase: ultrahigh-resolution crystal structure and multipolar atom model-based analysis.
Acta Crystallogr.,Sect.D, 71, 2015
8UD0
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BU of 8ud0 by Molmil
Sterile Alpha Motif (SAM) domain from Tric1 from Arabidopsis thaliana - G241E mutant
Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Chloroplastic import inner membrane translocase subunit HP30-1
Authors:Olasz, B, Vrielink, A, Smithers, L.
Deposit date:2023-09-27
Release date:2024-05-01
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural analysis of the SAM domain of the Arabidopsis mitochondrial tRNA import receptor.
J.Biol.Chem., 2024
8UCZ
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BU of 8ucz by Molmil
Sterile Alpha Motif (SAM) domain from Tric1 from Arabidopsis thaliana - D235A mutant
Descriptor: CHLORIDE ION, Chloroplastic import inner membrane translocase subunit HP30-1
Authors:Olasz, B, Vrielink, A, Smithers, L.
Deposit date:2023-09-27
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Structural analysis of the SAM domain of the Arabidopsis mitochondrial tRNA import receptor.
J.Biol.Chem., 2024
8F2G
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BU of 8f2g by Molmil
Crystal structure of Hen Egg White Lysozyme at 0.44 GPa
Descriptor: Lysozyme C
Authors:Marshall, A.C, Boer, S.A, Turner, G, Moggach, S.A, Bond, C.S, Vrielink, A.
Deposit date:2022-11-08
Release date:2022-12-07
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:High-pressure single-crystal diffraction at the Australian Synchrotron.
J.Synchrotron Radiat., 30, 2023
5FGN
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BU of 5fgn by Molmil
Integral membrane protein lipooligosaccharide phosphoethanolamine transferase A (EptA) from Neisseria meningitidis
Descriptor: 2-O-octyl-beta-D-glucopyranose, DODECYL-BETA-D-MALTOSIDE, ZINC ION, ...
Authors:Anandan, A, Vrielink, A.
Deposit date:2015-12-21
Release date:2017-02-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5KWF
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BU of 5kwf by Molmil
Joint X-ray Neutron Structure of Cholesterol Oxidase
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Golden, E, Vrielink, A, Meilleur, F, Blakeley, M.
Deposit date:2016-07-18
Release date:2017-02-01
Last modified:2024-03-06
Method:NEUTRON DIFFRACTION (1.499 Å), X-RAY DIFFRACTION
Cite:An extended N-H bond, driven by a conserved second-order interaction, orients the flavin N5 orbital in cholesterol oxidase.
Sci Rep, 7, 2017
1I19
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BU of 1i19 by Molmil
CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE FROM B.STEROLICUM
Descriptor: 1,2-ETHANEDIOL, CACODYLATE ION, CHOLESTEROL OXIDASE, ...
Authors:Coulombe, R, Yue, K.Q, Ghisla, S, Vrielink, A.
Deposit date:2001-01-31
Release date:2001-08-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair.
J.Biol.Chem., 276, 2001
4XWR
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BU of 4xwr by Molmil
X-ray structure of perdeuterated Cholesterol Oxidase from Streptomyces SA-COO
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Golden, E, Vrielink, A.
Deposit date:2015-01-29
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Production and characterization of recombinant perdeuterated cholesterol oxidase.
Anal.Biochem., 485, 2015
4XXG
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BU of 4xxg by Molmil
Structure of protonated Cholesterol Oxidase from Streptomyces SA-COO
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Golden, E, Vrielink, A.
Deposit date:2015-01-30
Release date:2015-12-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (0.85 Å)
Cite:Production and characterization of recombinant perdeuterated cholesterol oxidase.
Anal.Biochem., 485, 2015
8UCY
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BU of 8ucy by Molmil
Sterile Alpha Motif (SAM) domain from Tric1, Arabidopsis thaliana
Descriptor: CHLORIDE ION, Chloroplastic import inner membrane translocase subunit HP30-1
Authors:Olasz, B, Vrielink, A, Evans, G.L.
Deposit date:2023-09-27
Release date:2024-05-08
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Structural analysis of the SAM domain of the Arabidopsis mitochondrial tRNA import receptor.
J.Biol.Chem., 300, 2024
4U2T
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BU of 4u2t by Molmil
Cholesterol oxidase in the oxidised state complexed with isopropanol
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Golden, E.A, Vrielink, A.
Deposit date:2014-07-18
Release date:2014-12-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.223 Å)
Cite:High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization.
Acta Crystallogr.,Sect.D, 70, 2014
4U2L
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BU of 4u2l by Molmil
Dithionite reduced cholesterol in complex with sulfite
Descriptor: (S)-10-((2S,3S,4R)-5-((S)-((S)-(((2R,3S,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDROFURAN-2-YL)METHOXY)(HYDROXY)PHOSPHORYLOXY)(HYDROXY)PHOSPHORYLOXY)-2,3,4-TRIHYDROXYPENTYL)-7,8-DIMETHYL-2,4-DIOXO-2,3,4,4A-TETRAHYDROBENZO[G]PTERIDINE-5(10H)-SULFONIC ACID, Cholesterol oxidase, SULFATE ION
Authors:Golden, E.A, Vrielink, A.
Deposit date:2014-07-17
Release date:2014-12-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.337 Å)
Cite:High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization.
Acta Crystallogr.,Sect.D, 70, 2014
4U2S
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BU of 4u2s by Molmil
Cholesterol oxidase in the reduced state complexed with isopropanol
Descriptor: Cholesterol oxidase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Golden, E.A, Vrielink, A.
Deposit date:2014-07-18
Release date:2014-12-10
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.12 Å)
Cite:High-resolution structures of cholesterol oxidase in the reduced state provide insights into redox stabilization.
Acta Crystallogr.,Sect.D, 70, 2014
3GYJ
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BU of 3gyj by Molmil
Cholesterol oxidase from Streptomyces sp. N485L mutant (0.92A)
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Lyubimov, A.Y, Vrielink, A.
Deposit date:2009-04-03
Release date:2009-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase.
Acta Crystallogr.,Sect.D, 65, 2009
3GYI
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BU of 3gyi by Molmil
Cholesterol oxidase from Streptomyces sp. N485D mutant (1.0A)
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Lyubimov, A.Y, Vrielink, A.
Deposit date:2009-04-03
Release date:2009-12-01
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1 Å)
Cite:A hydrogen-bonding network is important for oxidation and isomerization in the reaction catalyzed by cholesterol oxidase.
Acta Crystallogr.,Sect.D, 65, 2009
1COY
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BU of 1coy by Molmil
CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES
Descriptor: 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, CHOLESTEROL OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Li, J, Vrielink, A, Brick, P, Blow, D.M.
Deposit date:1993-06-14
Release date:1993-10-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.
Biochemistry, 32, 1993
3CNJ
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BU of 3cnj by Molmil
Cholesterol oxidase from Streptomyces sp. F359W mutant (0.95A)
Descriptor: Cholesterol oxidase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Lyubimov, A.Y, Brammer, L, Vrielink, A.
Deposit date:2008-03-25
Release date:2008-04-29
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.95 Å)
Cite:The binding and release of oxygen and hydrogen peroxide are directed by a hydrophobic tunnel in cholesterol oxidase
Biochemistry, 47, 2008
1QD1
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BU of 1qd1 by Molmil
THE CRYSTAL STRUCTURE OF THE FORMIMINOTRANSFERASE DOMAIN OF FORMIMINOTRANSFERASE-CYCLODEAMINASE.
Descriptor: FORMIMINOTRANSFERASE-CYCLODEAMINASE, GLYCEROL, N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid
Authors:Kohls, D, Sulea, T, Purisima, E, MacKenzie, R.E, Vrielink, A.
Deposit date:1999-07-08
Release date:2000-01-12
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structure of the formiminotransferase domain of formiminotransferase-cyclodeaminase: implications for substrate channeling in a bifunctional enzyme.
Structure Fold.Des., 8, 2000
3B6D
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BU of 3b6d by Molmil
Crystal Structure of Streptomyces Cholesterol Oxidase H447Q/E361Q mutant (1.2A)
Descriptor: Cholesterol oxidase, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, SULFATE ION
Authors:Lyubimov, A.Y, Vrielink, A.
Deposit date:2007-10-29
Release date:2007-12-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase
Protein Sci., 16, 2007
3B3R
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BU of 3b3r by Molmil
Crystal structure of Streptomyces cholesterol oxidase H447Q/E361Q mutant bound to glycerol (0.98A)
Descriptor: Cholesterol oxidase, FLAVIN-N7 PROTONATED-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Lyubimov, A.Y, Heard, K, Tang, H, Sampson, N.S, Vrielink, A.
Deposit date:2007-10-22
Release date:2007-12-18
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (0.98 Å)
Cite:Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase
Protein Sci., 16, 2007
2IID
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BU of 2iid by Molmil
Structure of L-amino acid oxidase from Calloselasma rhodostoma in complex with L-phenylalanine
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, L-amino-acid oxidase, ...
Authors:Moustafa, I.M, Foster, S, Lyubimov, A.Y, Vrielink, A.
Deposit date:2006-09-27
Release date:2006-10-31
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of LAAO from Calloselasma rhodostoma with an L-Phenylalanine Substrate: Insights into Structure and Mechanism
J.Mol.Biol., 364, 2006
1EZ0
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BU of 1ez0 by Molmil
CRYSTAL STRUCTURE OF THE NADP+ DEPENDENT ALDEHYDE DEHYDROGENASE FROM VIBRIO HARVEYI.
Descriptor: ALDEHYDE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ahvazi, B, Coulombe, R, Delarge, M, Vedadi, M, Zhang, L, Meighen, E, Vrielink, A.
Deposit date:2000-05-09
Release date:2000-05-24
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity.
Biochem.J., 349, 2000
1EYY
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BU of 1eyy by Molmil
CRYSTAL STRUCTURE OF THE NADP+ DEPENDENT ALDEHYDE DEHYDROGENASE FROM VIBRIO HARVEYI.
Descriptor: ALDEHYDE DEHYDROGENASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Ahvazi, B, Coulombe, R, Delarge, M, Vedadi, M, Zhang, L, Meighen, E, Vrielink, A.
Deposit date:2000-05-09
Release date:2000-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the NADP+-dependent aldehyde dehydrogenase from Vibrio harveyi: structural implications for cofactor specificity and affinity.
Biochem.J., 349, 2000

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